The reviewers found the manuscript on inflammation's role in cancer stem cells to be relevant but suggested it needs clarity, more background information, discussion on immune cells' role in tumors, updated references, and grammar corrections.
12 citations,
November 2014 in “PLOS Computational Biology” The study concluded that hair growth in mice is regulated by a stable interaction between skin cell types, and disrupting this can cause hair loss.
5 citations,
September 2020 in “Molecules” Extracts from three Polynesian plants were found to promote hair growth by affecting cell growth and gene expression related to hair.
26 citations,
May 2013 in “Marine Drugs” Ishige sinicola, a type of seaweed, may help hair grow by blocking a hair loss-related enzyme and boosting important cell growth.
April 2018 in “The journal of investigative dermatology/Journal of investigative dermatology” Skin heals with scars because only one type of fibroblast is used, not a mix.
29 citations,
December 2019 in “Transfusion and Apheresis Science” Platelet-derived bio-products help in wound healing and tissue regeneration but lack standardized methods, and their use in medicine is growing.
8 citations,
February 2021 in “Biomolecules & therapeutics” Myristoleic acid helps hair growth by boosting cell growth and recycling processes in hair follicle cells.
August 2016 in “Journal of Investigative Dermatology” Zinc deficiency disrupts hair growth and cycle, but zinc supplements can fix this.
139 citations,
December 2020 in “Cell Stem Cell” Male hormones affect COVID-19 severity and certain drugs targeting these hormones could help reduce the risk.
51 citations,
April 2020 in “Cells” Special cell particles from macrophages can help hair grow.
47 citations,
December 2019 in “Biomaterials” Scientists have created a new hair loss treatment using ultrasound to deliver gene-editing particles, which resulted in up to 90% hair regrowth in mice.
42 citations,
February 2018 in “International Journal of Molecular Sciences” Minoxidil boosts hair growth by triggering growth factor release from specific stem cells.
40 citations,
March 2017 in “The journal of investigative dermatology/Journal of investigative dermatology” Growing hair follicles have high mitochondrial activity and ROS in specific regions, aiding hair formation.
36 citations,
June 2018 in “Journal of Dermatology” Use finasteride, dutasteride, and minoxidil for hair loss treatment.
29 citations,
March 2016 in “Cell cycle/Cell cycle (Georgetown, Tex. Online)” Isoproterenol helps hair follicle stem cells turn into beating heart muscle cells.
17 citations,
June 2011 in “The journal of investigative dermatology/Journal of investigative dermatology” The G60S Connexin43 mutation causes hair growth issues and poor hair quality in mice, similar to human ODDD patients.
14 citations,
April 2011 in “Cell Proliferation” Scientists can grow human hair follicle stem cells in a lab without changing their nature, which could help treat hair loss.
8 citations,
November 2020 in “Nature Communications” Adult stem cells with Tp63 can form hair and skin cells when placed in new skin, showing they have hidden abilities for skin repair.
5 citations,
November 2020 in “Cells” Placental mesenchymal stem cells and their conditioned medium significantly improve healing in local radiation injuries.
New treatments for hair loss, including a compound called "ALRV5XR", platelet-rich plasma, and Adult Stem Cell-based therapy, are showing promise, but more trials are needed for confirmation.
1 citations,
August 2023 in “Nature communications” Hdac1 and Hdac2 help maintain and protect the cells that control hair growth.
August 2024 in “Food Bioscience” Bifidobacterium longum BB536 metabolites may help treat hair loss by repairing and promoting hair cell growth.
January 2022 in “Pastic and aesthetic research” PRP helps skin regeneration but needs standardized testing for consistent results.
November 2015 in “Hair transplant forum international” Early attempts at using cloned cells for hair transplants failed, but 3D cell growth showed some promise.
1057 citations,
November 2011 in “Annals of Biomedical Engineering” Low-level Laser Therapy may help reduce inflammation, pain, and aid healing, but more research is needed to confirm its effectiveness and establish standard treatment guidelines.
316 citations,
June 2017 in “Stem Cell Research & Therapy” Fat tissue-derived cells show promise for repairing body tissues, but more research and regulation are needed for safe use.
119 citations,
January 2014 in “Indian Journal of Dermatology, Venereology and Leprology” Platelet-rich plasma might help with hair growth and skin conditions, but more research is needed to prove its effectiveness and safety.
82 citations,
March 2012 in “Development” Drosha and Dicer are essential for hair follicle health and preventing DNA damage in skin cells.
79 citations,
March 1999 in “The journal of investigative dermatology/Journal of investigative dermatology” Procyanidin compounds from grape seeds were found to significantly increase mouse hair growth.
76 citations,
August 2018 in “International Journal of Cosmetic Science” Dermal Papilla cells are a promising tool for evaluating hair growth treatments.