3 citations
,
June 2006 in “Expert Review of Dermatology” This review discusses recent advances in hair follicle research, highlighting therapeutic and cosmetic applications, but reports no new study results.
133 citations
,
September 2013 in “Nature Reviews Molecular Cell Biology” Different types of stem cells and their environments are key to skin repair and maintenance.
3 citations
,
December 2000 in “International Journal of Cosmetic Science” This study established that a human epidermal model can be utilized to assess 5alpha-reductase activity and evaluate enzyme modulators, such as finasteride, for dermatological applications.
9 citations
,
October 2008 in “Mutation research” This article discusses the genomic and postgenomic changes in chronic degenerative diseases and cardiovascular and skin disease contexts, highlighting potential modulation through diet and pharmacological interventions without presenting new experimental results.
76 citations
,
January 2017 in “World Journal of Stem Cells” This review discusses the potential applications of adipose-derived stromal cells for treating conditions like colitis, liver failure, and more, without presenting new clinical results.
20 citations
,
January 2022 in “Oxidative Medicine and Cellular Longevity” This study found that intrinsic reactive oxygen species drive the hair follicle cycle progression through DNA damage and repair, apoptosis, and macrophage polarization, influencing hair loss and regeneration dynamics in mice.
31 citations
,
April 2016 in “Nature communications” This study found that in adult mouse skin, reduced levels of histone H3 K4/K9/K27me3 during hair follicle stem cell quiescence are linked to proper tissue homeostasis.
April 2025 in “International Journal of Pharmaceutical Sciences Review and Research” This study found that SesZen-Bio TM, a proprietary extract from Sesbania grandiflora leaves, increased proliferation of hair cells and hair shaft length in vitro and ex vivo, potentially due to activation of the Wnt/β-catenin signaling and stem cell differentiation pathways.
182 citations
,
May 2003 in “Development” This study found that Myc activation in mouse epidermis impairs keratinocyte adhesion and motility by downregulating extracellular matrix and cytoskeleton proteins, affecting hair lineage differentiation.
103 citations
,
November 2014 in “Journal of Cell Biology” This study found that overexpression of miR-214 in keratinocytes inhibits hair follicle development and cycling by targeting β-catenin in the Wnt signaling pathway.
August 2026 in “Molecular and Cellular Biochemistry” This study found that administering tolerogenic dendritic cell-conditioned medium to dihydrotestosterone-treated mice promoted hair regrowth by modulating the follicular microenvironment, reducing pro-inflammatory cytokines, and activating key signaling pathways, highlighting its potential as a treatment for androgenetic alopecia.
28 citations
,
July 2007 in “Development” In this study, inactivating the TAF4 subunit of transcription factor TFIID in mouse epidermis disrupted gene expression linked to skin and hair function, and increased tumor risk.
112 citations
,
February 2001 in “Journal of Investigative Dermatology” This study found that substance P and calcitonin-gene-related peptide have different roles in regulating hair growth in mice, with substance P promoting anagen progression and calcitonin-gene-related peptide inhibiting it.
99 citations
,
May 1998 in “Journal of biological chemistry/The Journal of biological chemistry” This study found that small proline-rich proteins modify the biomechanical properties of cornified cell envelopes in rodent forestomachs, potentially affecting the tissue's ability to withstand mechanical stress.
24 citations
,
January 2022 in “Journal of Nanobiotechnology” This study found that quaternary ammonium iminofullerenes (IFQA) can alleviate oxidative stress in maize caused by hydrogen peroxide, promoting root growth by enhancing antioxidant cycles and reducing ROS accumulation.
14 citations
,
March 2022 in “Journal of Biomedical Science” In this study, Cyanidin 3-O-arabinoside was found to protect against DHT-induced dermal papilla cell senescence and mitochondrial dysfunction in androgenetic alopecia, restoring hair growth in mouse models.
3 citations
,
April 2016 in “Food Science and Biotechnology” This study found that Oriental melon leaf extracts promoted hair growth in a mouse model and cultured human hair follicles, suggesting potential use as a treatment for hair loss.
50 citations
,
May 2020 in “FEBS Letters” This review discusses techniques for analyzing the cell cycle, highlighting emerging tools for measuring cell cycle speed at single-cell resolution in live animals, and reports no new results.
4 citations
,
October 2014 in “Journal of Integrative Agriculture” This study identified 417 genes with differential expression at varying stages of cashmere growth in goats, highlighting their potential role in tissue remodeling and cashmere regeneration.
February 2026 in “Advanced Science” This study found that the combination of TTNPB and CHIR99021 enhanced the derivation of highly advanced neural stem cells from human pluripotent stem cells, with improved chromatin accessibility and neuroectodermal gene expression, and these cells successfully engrafted in rat hippocampi to ameliorate depression-like symptoms.
6 citations
,
July 2023 in “Plants” This study found that Datura metel extracts obtained through supercritical CO2 extraction demonstrated significant biological activity, including antioxidant and anti-inflammatory properties, and effectively promoted wound closure and collagen preservation, comparable to standard treatments, in laboratory experiments.
February 2025 in “Natural Product Communications” This study found that combining natural extracts significantly boosted the stem cell functions of dermal papilla cells by enhancing β-catenin stability, promoting hair growth potential in vitro.
76 citations
,
August 2018 in “International Journal of Cosmetic Science” This review discusses the use of Dermal Papilla cells as in vitro models for studying hair growth modulators, emphasizing their role in aiding the development of new hair treatments, but reports no new clinical results.
47 citations
,
March 2019 in “Journal of immunology research” This review discusses the effects of valproic acid on immune cell activation and gene expression, potentially influencing infection outcomes and suggesting its promise for autoimmune and hypersensitivity condition management.
28 citations
,
March 2019 in “Journal of Dermatological Science” This review discusses methods for evaluating hair growth-promoting effects of candidate substances for androgenetic alopecia, focusing on cell assays, organ cultures, and animal models, and reports no new results.
13 citations
,
January 2020 in “Scientific Reports” This study found distinct differences in protein expression and wound healing pathways between Acomys cahirinus and Mus musculus, highlighting potential targets for reducing fibrotic response in mammals.
1 citations
,
May 2006 in “Expert Opinion on Therapeutic Patents” This review summarizes 19 patents filed since 2000 for treating or preventing chemotherapy-induced alopecia, but reports no new clinical findings.
2 citations
,
June 2022 in “International Journal of Molecular Sciences” This study found variable outcomes in hair loss treatment with autologous cell-based therapy using DSC cells, with certain gene markers showing inconsistent correlations with treatment efficacy.
June 2008 in “Experimental dermatology” This research found that melatonin plays a protective and modulatory role in skin biology, reducing UV damage and chemotherapy-induced hair follicle cell harm in human organ culture models.
8 citations
,
January 2016 in “Journal of Investigative Dermatology” This review discusses the use of the human-on-mouse xenograft model for studying the human hair follicle cycle and emphasizes its utility for pharmacological testing, without reporting new clinical results.