Wound Healing Effect of Supercritical Carbon Dioxide Datura Metel L. Leaves Extracts: An In Vitro Study of Anti-Inflammation, Cell Migration, MMP-2 Inhibition, and the Modulation of the Sonic Hedgehog Pathway in Human Fibroblasts

    July 2023 in “ Plants
    Warintorn Ruksiriwanich, Pichchapa Linsaenkart, Anurak Muangsanguan … Francisco J. Barba
    Studysummary This study found that Datura metel extracts obtained through supercritical CO2 extraction demonstrated significant biological activity, including antioxidant and anti-inflammatory properties, and effectively promoted wound closure and collagen preservation, comparable to standard treatments, in laboratory experiments.
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    4. In Vitro and In Vivo Regulation of SRD5A mRNA Expression of Supercritical Carbon Dioxide Extract from Asparagus Racemosus Root as Anti-Sebum and Pore-Minimizing Active Ingredients Molecules · 2022
    5. Wound Healing: Cellular Mechanisms and Pathological Outcomes Open Biology · 2020
    6. Scars Or Regeneration? Dermal Fibroblasts As Drivers Of Diverse Skin Wound Responses International Journal of Molecular Sciences · 2020
    7. Through the Lens of Hair Follicle Neogenesis: A New Focus on Mechanisms of Skin Regeneration After Wounding Seminars in Cell & Developmental Biology · 2019