13 citations,
August 2020 in “Frontiers in Cell and Developmental Biology” Twist1 helps maintain important features of cells crucial for hair growth by working with Tcf4 and β-catenin.
April 2024 in “Histochemistry and cell biology” N-acetylcysteine may prevent hair loss caused by chemotherapy.
November 2005 in “Nature Reviews Molecular Cell Biology” The protein hairless is important for hair regrowth because it stops the protein wise from blocking the hair cycle.
93 citations,
January 2007 in “The International Journal of Biochemistry & Cell Biology” Melanocytes are crucial for skin pigmentation and can affect conditions like melanoma, vitiligo, and albinism, as well as hair color and hearing.
23 citations,
June 2019 in “Biochimica and biophysica acta. Molecular and cell biology of lipids” Different sPLA2 enzymes affect immunity, skin and hair health, reproduction, and may be potential targets for therapy.
15 citations,
March 2014 in “Biochimica and biophysica acta. Molecular and cell biology of lipids” ACBP is essential for healthy skin and fur by maintaining the skin's barrier function.
12 citations,
January 2014 in “Cell structure and function” Different combinations of human hair keratins affect how hair fibers form.
240 citations,
May 2011 in “Pigment Cell & Melanoma Research” Melanocyte stem cells in hair follicles are key for hair color and could help treat greying and pigment disorders.
38 citations,
August 2018 in “Plant & cell physiology/Plant and cell physiology” Changing the amount of PLC5 in Arabidopsis affects root growth and drought resistance, with less PLC5 slowing root growth and more PLC5 improving drought tolerance but hindering root hair growth.
38 citations,
June 2005 in “Matrix Biology” Minoxidil affects collagen-related genes, potentially helping treat fibrosis.
30 citations,
April 2010 in “Cell Cycle” The gene p53 is crucial for removing damaged cells to allow for healthy tissue renewal.
13 citations,
August 2012 in “Pigment Cell & Melanoma Research” A mutation in the Adam10 gene causes freckle-like spots on Hairless mice.
8 citations,
March 2019 in “Open Biology” The document concludes that regenerating functional ectodermal organs like teeth and hair is promising for future therapies.
97 citations,
March 2002 in “Molecular and cellular biology” Mutant CDP/Cux protein causes hair defects and reduced male fertility in mice.
36 citations,
April 2013 in “Cell and Tissue Research” Bone-marrow and epidermal stem cells help heal wounds differently, with bone-marrow cells aiding in blood vessel formation and epidermal cells in hair growth.
35 citations,
February 2005 in “Biology of Reproduction” PNU157706 reduced rat sperm movement and fertility without affecting offspring health.
20 citations,
June 2020 in “Stem Cell Research & Therapy” Using stem cells from fat tissue can significantly improve wound healing in dogs.
8 citations,
January 2017 in “Methods in molecular biology” Stem cells rearrangement regenerates functional hair follicles, potentially treating hair loss.
85 citations,
July 2012 in “Cold Spring Harbor perspectives in biology” The skin protects the body and is constantly renewed by stem cells; disruptions can lead to cancer.
53 citations,
September 2020 in “Stem Cell Research & Therapy” New methods to improve the healing abilities of mesenchymal stem cells for disease treatment are promising but need more research.
37 citations,
March 2012 in “International Journal of Radiation Biology” Mobile phone radiation can cause DNA damage in human hair root cells.
25 citations,
May 2013 in “Journal of mammary gland biology and neoplasia” Hedgehog signaling is crucial for mammary gland development over hair follicles.
10 citations,
September 2014 in “The Journal of Steroid Biochemistry and Molecular Biology” Allopregnanolone increases KCC2 expression in baby male rats' brains, while finasteride doesn't affect it.
October 2023 in “International journal of biology, pharmacy and allied sciences” Henna helps wounds heal faster and better.
56 citations,
July 2006 in “American journal of physiology. Cell physiology” Steroid sex hormones activate matriptase in prostate cancer cells but not in breast cancer cells.
51 citations,
September 2013 in “The Journal of Steroid Biochemistry and Molecular Biology” Certain drugs that block specific enzymes can help treat prostate diseases.
28 citations,
January 2019 in “Journal of structural biology” Different populations have distinct hair structures related to their ancestry.
11 citations,
February 2012 in “Journal of cell science” Rac1 is essential for proper hair structure and color.
10 citations,
April 2000 in “Archives of Oral Biology” Minocycline may cause hair loss by increasing DHT levels, but finasteride can help counteract this effect.
8 citations,
November 2017 in “The Journal of Steroid Biochemistry and Molecular Biology” DHT affects testicular development and regulates spermatogenesis in some fish.