research Human Skin Stem Cells and the Aging Process
Skin aging is due to impaired stem cell mobilization or fewer responsive stem cells.
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research Accelerated Senescence in Skin in a Murine Model of Radiation-Induced Multi-Organ Injury
High-dose radiation speeds up aging in skin stem cells.
research Phloroglucinol Enhances Anagen Signaling and Alleviates H2O2-Induced Oxidative Stress in Human Dermal Papilla Cells
Phloroglucinol may help improve hair loss by promoting hair growth and reducing oxidative stress.
research Glycome Profiling by Lectin Microarray Reveals Dynamic Glycan Alterations During Epidermal Stem Cell Aging
Aging changes sugar molecules on skin stem cells, which may affect their ability to repair skin.
research A Systematic Review of Anti-Aging Effects of 23 Traditional Chinese Medicines
Some traditional Chinese medicines may have anti-aging benefits and could help with hair growth, but more research is needed.
research Hair Growth Stimulation by a Natural Remedy: Animal Studies
The plant extract remedy Satura® Rosta promotes hair growth and regrowth without negative effects.
research Toll-Like Receptor 4 (TLR4): New Insights into Immunity and Aging
TLR4 is important in aging-related diseases and could be a new treatment target.
research The Role of Box A of HMGB1 in Enhancing Stem Cell Properties of Human Mesenchymal Cells: A Novel Approach for the Pursuit of Anti-Aging Therapy
Box A of HMGB1 can improve stem cell function, aiding anti-aging therapy.
research Minoxidil Regulates Aging-Like Phenotypes in Rat Cortical Astrocytes In Vitro
Minoxidil may help reduce aging effects in brain cells.
research Elucidating the Anti-Aging Mechanism of Si Jun Zi Tang by Integrating Network Pharmacology and Experimental Validation In Vivo
Si Jun Zi Tang may slow aging by affecting specific cell signaling pathways.
research Control by a Hair’s Breadth: The Role of MicroRNAs in the Skin
MicroRNAs play a crucial role in skin and hair health, affecting everything from growth to aging, and could potentially be used in treating skin diseases.
research Identifying Molecular Targets for Reverse Aging Using Integrated Network Analysis of Transcriptomic and Epigenomic Changes During Aging
Curcumin may help reverse aging by targeting specific genes.
research Mucosal TLR5 Activation Controls Healthspan and Longevity
Activating TLR5 in the gut can extend lifespan and improve health in aged mice.
research Stress-Sensing in the Human Greying Hair Follicle: Ataxia Telangiectasia Mutated (ATM) Depletion in Hair Bulb Melanocytes in Canities-Prone Scalp
Hair greying is linked to reduced ATM protein in hair cells, which protects against stress and damage.
research Dermal Niche Signaling and Epidermal Stem Cells
Skin health and repair depend on the signals between skin stem cells and their surrounding cells.
research Metabolic Regulation of Stem Cells in Aging
Eating less can improve stem cell function and increase lifespan.
research Basal Keratinocytes Exhibit Age-Related Epigenetic and Transcriptomic Alterations Resulting in an Altered Metabolic Profile
Aging changes skin cells, leading to different DNA methylation and gene activity, affecting cell metabolism and aging signs.
research Adipocytes in Skin Health and Disease
Fat cells are important for healthy skin, hair growth, and healing, and changes in these cells can affect skin conditions and aging.
research Present and Future Use of Exosomes in Dermatology
Exosomes could be key in treating skin conditions and healing wounds.
research Appearance and Internal Aging
Looking older on the outside might be linked to aging faster on the inside and can be affected by lifestyle choices and health risks.
research Pathology of Mouse Models of Accelerated Aging
Progeroid mouse models show signs of early aging similar to humans, helping us understand aging better.
research Possible Role of Autophagy Activation in Stimulation of Regeneration
The document suggests that activating autophagy might help with regeneration by removing old and damaged cells.
research Hedgehog Signaling Maintains Hair Follicle Stem Cell Phenotype in Young and Aged Human Skin
Hedgehog signaling helps keep hair follicle stem cells the same in both young and old human skin.
research Expression of Anti-Aging Type-XVII Collagen (COL17A1/BP180) in Hair Follicle-Associated Pluripotent (HAP) Stem Cells During Differentiation
Hair stem cells produce a protein called COL17A1 that plays a key role in their development and is linked to hair thinning and baldness.
research What's New in Dermatological Research?
2011 dermatological research found new skin aging markers, hair loss causes, skin defense mechanisms, and potential for new treatments.
research DermaCult Keratinocyte Expansion Medium: A Serum- and BPE-Free Medium Supporting Long-Term Feeder-Free Expansion of Primary Human Epidermal and Pluripotent Stem Cell-Derived Keratinocytes
DermaCult™ Keratinocyte Expansion Medium allows human skin cells to grow longer while keeping their ability to develop properly.
research Shedding Light on the Effects of Calorie Restriction and Its Mimetics on Skin Biology
Eating fewer calories may slow skin aging and improve skin health through various biological changes.
research Isolation of an Early Transit Amplifying Keratinocyte Population in Interfollicular Human Epidermis: A Role for CD271 Receptor
Scientists found a new type of skin cell that could help with skin repair and these cells work better with a certain protein.
research Recent Advances on Skin-Resident Stem/Progenitor Cell Functions in Skin Regeneration, Aging, and Cancers and Novel Anti-Aging and Cancer Therapies
New treatments targeting skin stem cells show promise for skin repair, anti-aging, and cancer therapy.
research Progressive Alopecia Reveals Decreasing Stem Cell Activation Probability During Aging of Mice with Epidermal Deletion of DNA Methyltransferase 1
Mice lacking a key DNA methylation enzyme in skin cells have a lower chance of activating stem cells necessary for hair growth, leading to progressive hair loss.