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This review discusses the therapeutic potential of costunolide for various diseases, highlighting its bioactivity and mechanisms, but it reports no new experimental results.

This review examines the differential aging of melanocytes in hair follicles and skin, and reports no new findings; the authors suggest further research is needed to understand these processes.

In this study, researchers found that exposure to PM10 significantly increased inflammation and impaired collagen synthesis in human dermal fibroblasts, suggesting PM10 contributes to skin aging through these mechanisms.

This review discusses the dual role of tissue-resident memory T cells in providing immune protection against infections and cancer and contributing to autoimmune skin disease pathology, without presenting new experimental results.

This study demonstrated that a c-Kit-CreER-driven mouse model confirms melanocyte stem cells as a genuine source of melanoma, paralleling human melanoma in heterogeneity and gene signatures.

This paper highlights the need for a comprehensive red ginseng monograph to provide standardized information on its components, certified functionality, efficacy, action mechanisms, and safety, especially given its widespread use as a health functional food in South Korea and interest in its benefits worldwide.

This article reviews the role of perifollicular regulatory T cells in maintaining hair follicle integrity in the context of hidradenitis suppurativa and calls attention to inflammatory mechanisms without reporting new clinical results.

This review discusses the causes, clinical presentation, and management of anagen effluvium, emphasizing its psychological impact and the need for empathy and practical support, but reports no new results.

This study found distinct gene expression profiles in alopecia areata-affected skin, suggesting T-cell mediated immune responses and unique gene profiles between different stages of the disease.

This study suggests that CD8+ cytotoxic T lymphocytes play a crucial role in the development of alopecia areata, based on observations in rodent models that mimic human autoimmune disease.

This study observed that in aged mouse skin, there was an increase in IL-17-expressing T helper cells, γδ T cells, and innate lymphoid cells, and blocking IL-17 signaling reduced skin inflammation and delayed age-related changes, suggesting it as a potential target to mitigate skin aging.

This study found that AR/VDR-targeted agonist hormone therapy can inhibit cell viability in HR2-av triple-negative breast cancer cell lines through multiple mechanisms and may enhance the effects of chemotherapy.

In this study, enteroendocrine cells were shown to coordinate intestinal stem cell migration towards a wound in Drosophila by releasing a ligand that activates non-canonical Wnt signaling, aiding efficient tissue repair.

This review discusses the roles of immune responses and cells in skin health and disease, emphasizing recent insights into their mechanisms and potential therapeutic applications, but presents no new experimental results.

Hair can regrow after certain stem cells are lost because other stem cells can take over their role.

This study found that H-Ras activation in aged mouse skin leads to increased dysplasia and progression to in situ squamous cell carcinoma, highlighting an age-linked connection between immune changes, senescence, and cancer risk.

This article discusses the complex role of TGFβ in cancer progression, highlighting its dual function as both a tumor suppressor in early stages and a promoter in later stages, without reporting new results.

This review discusses the origins of skin and esophageal cancers and reports no clinical results; it emphasizes the role of cyclooxygenase-2 in tumorigenesis and differentiation.

This review highlights recent insights into how IL-15 influences T cell responses and contributes to immunopathogenesis in various diseases, suggesting its crucial role in TCR-independent activation and potential in optimizing therapeutic strategies.

This study found that lymphatic vessels in mice are important for hair follicle development and organization, as their depletion blocks hair growth.

This review discusses interventions for chemotherapy-induced hair loss and reports no new clinical results; scalp cooling and nutritional support are considered potential strategies but not yet substantiated.

This review discusses the role of phytochemical nanoparticles in cervical cancer therapy and reports no new clinical results; the authors highlight their potential advantages over conventional chemotherapy.

This study found that vitamin C increased the survival, proliferation, and hair-regenerative potential of adipose-derived stem cells through the MAPK pathway and enhanced hair growth in mice.

This review discusses the potential of JAK inhibitors as a promising treatment strategy for alopecia areata, highlighting their mechanism and recent FDA approval based on clinical trial efficacy.

This study found that deleting Stim1 and Stim2 in mature T regulatory cells disrupts Ca 2+ signaling, preventing their differentiation and leading to severe autoimmune disorders in mice.

The authors describe drug repurposing as a promising strategy for finding new uses for existing drugs, noting it is efficient, cost-effective, and poses lower risks than traditional drug discovery processes, potentially aiding in the treatment of rare and difficult-to-treat diseases.

This study found that Par3 plays a crucial role in maintaining epidermal homeostasis by regulating Rho/actomyosin contractility and ensuring mitotic accuracy, with potential implications for other self-renewing epithelia.

This source reports that scalp cooling is currently the only safe and FDA-cleared method to potentially reduce chemotherapy-induced hair loss, with about a 50% chance of maintaining sufficient hair to avoid needing a wig.

This review discusses immunohistological and immunofluorescent methods for studying the human hair follicle cell cycle, reporting no new results, and suggests its potential for advancing cell cycle research.

This review addresses the role of skin-resident adult stem/progenitor cells in skin homeostasis, disease, and cancer development, and reports no new research results.