research Advances in the Management of Alopecia Areata
New treatments for severe hair loss often fail, but some patients see hair regrowth with specific therapies, and treatment should be tailored to the individual's situation.
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research The Effects of Androgens on T Cells: Clues to Female Predominance in Autoimmune Liver Diseases
Androgens may influence T cells, contributing to higher autoimmune liver disease risk in women.
research Human FOXN1 Deficiency Is Associated with Alpha Beta Double-Negative and FoxP3 Positive T-Cell Expansions That Are Distinctly Modulated upon Thymic Transplantation
Thymic transplantation normalized some T-cells but not others, maintaining immune function.
research Regulatory T Cells Are Required for Normal and Activin-Promoted Wound Repair in Mice
Regulatory T cells are essential for normal and improved wound healing in mice.
research Risk Factors and Characterization of Vitiligo and Alopecia Areata in Patients With Chronic Graft-Versus-Host Disease
Female donor to male recipient sex mismatch and positive ACA-IgG are key risk factors for vitiligo and alopecia areata in chronic GvHD patients.
research Esrp1-Regulated Splicing of Arhgef11 Isoforms Is Required for Epithelial Tight Junction Integrity
The study concluded that specific proteins are necessary to maintain the structure that holds epithelial cells tightly together.
research Regulatory T Cells in Autoimmune Skin Diseases
Treg dysfunction is linked to various autoimmune skin diseases, and understanding Treg properties is key for new treatments.
research The Probable Destructive Mechanisms Behind COVID-19 on Male Reproductive System and Fertility
COVID-19 may harm male fertility and damage the reproductive system.
research COVID-19 Pandemic: What About the Gonads?
COVID-19 may affect male fertility and women might have better outcomes due to hormonal and immune differences.
research A Primary Adrenal Non-Hodgkin's Lymphoma Presenting as an Incidental Adrenal Mass
A woman's small, unnoticed adrenal mass turned out to be a rare non-Hodgkin's lymphoma, treated successfully with surgery and therapy.
research Mesenchymal Stem Cell-Derived Exosomes for Organ Development and Cell-Free Therapy
MSC-Exos can aid organ development and offer therapeutic benefits for various conditions.
research Advanced Glycation End-Products Inhibit Mesenchymal-Epidermal Interaction by Up-Regulating Proinflammatory Cytokines in Hair Follicles
AGEs may cause hair loss by increasing inflammation in hair follicles.
research Treatment of Full-Thickness Skin Wounds with Blood-Derived CD34+ Precursor Cells Enhances Healing with Hair Follicle Regeneration
Blood-derived CD34+ cells speed up healing, reduce scarring, and regrow hair in skin wounds.
research NF-κB in Biology and Targeted Therapy: New Insights and Translational Implications
NF-κB signaling is crucial in many diseases and can be targeted for new treatments.
research Characterization of CD4+ Stem Cells of the Skin and Their Role in Skin Homeostasis and Tumorigenesis
CD4+ skin cells may be precursors to basal cell carcinoma.
research Developing Human Fetal Skin Demonstrates a Unique Lymphocyte Signature
Fetal skin has unique immune cells different from adult skin.
research Jagged-1+ Skin Tregs Modulate the Innate Immune Response to Wound Healing
Jagged-1 in skin Tregs is crucial for timely wound healing by recruiting specific immune cells.
research Research Advances of Tissue-Derived Extracellular Vesicles in Cancers
Tissue-derived extracellular vesicles are crucial for cancer diagnosis, prognosis, and treatment.
research An Overview of Anti-Inflammatory, Antioxidant, Anti-Cancer, Anti-Hyperlipidemic, Neuroprotective and Muscle Relaxant Effects of Natural Flavonoid, Apigenin; A Review
Apigenin, found in plants and vegetables, has many health benefits, including anti-inflammatory, antioxidant, and anticancer effects.
research Integrated-Omics Profiling Unveils the Disparities of Host Defense to ECM Scaffolds During Wound Healing in Aged Individuals
Aged individuals heal wounds less effectively due to specific immune cell issues.
research Effect of Topical Gel Administration of Secretome Hypoxia Mesenchymal Stem Cells on IL-10 and TNF-α Gene Expression: An In Vivo Experimental Study in Male Wistar Rats with Fluconazole-Induced Alopecia
SH-MSCs gel can effectively treat alopecia by increasing IL-10 and decreasing TNF-α gene expression.
research Alopecia Areata Triggered by Psychological Stress and Successfully Treated with a Janus Kinase Inhibitor: Case Report
Stress-related hair loss was reversed with a special medication.
research Optimization and Characterization of a Focal Dermal Hypoplasia Mouse Model to Test Potential Treatments
Li2CO3 improved skin disease in a mouse model of Focal Dermal Hypoplasia without toxicity.
research TLR3 Signaling Modulates Immunomodulatory Property of Human Periodontal Ligament Stem Cells
TLR3 signaling enhances the immunosuppressive properties of human periodontal ligament stem cells.
research Dermatological Drugs, Topical Agents, and Cosmetics
Tretinoin gel is safe for sun exposure, but tacalcitol doesn't significantly improve non-segmental vitiligo.
research The Murine Hair Follicle Is a Melatonin Target
Melatonin directly affects mouse hair follicles and may influence hair growth.
research Molecular Regulation and Cellular Heterogeneity in Skin Repair and Hair Follicle Regeneration
Ovol2 is crucial for hair growth and skin healing by controlling cell movement and growth.
research Mycosis Fungoides in Elderly Adults: A Diagnostic Challenge
Diagnosing mycosis fungoides, a rare skin cancer, is difficult in elderly adults and requires careful examination to avoid mistaking it for less serious skin conditions.
research TLR9 Activation in Large Wound Induces Tissue Repair and Hair Follicle Regeneration via γδT Cells
Activating TLR9 helps heal wounds and regrow hair by using specific immune cells.
research Leukemia Cutis of the Scalp Masquerading as Kerion in a Child
Leukemia can sometimes appear as unusual skin issues in children.