research Coda
November 2018 in “Princeton University Press eBooks” This chapter discusses the roles of vitamin C in brain function and its potential impact on behavior during periods of deficiency, reporting no new experimental findings.
76 citations
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July 2019 in “Scientific Reports” This study found that baicalin delivery through polymeric nanocapsules significantly enhanced its anticancer activity in breast cancer cell lines MCF-7 and MDA-MB-231.
May 2023 in “Frontiers in Pharmacology” Water extract of cacumen platycladi helps hair growth by affecting specific cell pathways.
2 citations
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February 2018 in “Journal of bone oncology” This study found that low-dose chemotherapy for solitary bone lesions of Langerhans cell histiocytosis in children led to quicker recovery, higher quality of life at 3 months, and was more cost-effective compared to surgery.
This study found that lysine carboxymethyl cysteinate helps protect the epidermis from UVB-induced damage by activating autophagy and restoring cornification processes in a skin model.
21 citations
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September 2010 in “Cancer Prevention Research” This study suggests that IGFBP-2 may play a role in basal cell carcinoma development by mediating epidermal progenitor cell expansion in hair follicles with activated Shh signaling.
4 citations
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December 2024 in “Clinical Cosmetic and Investigational Dermatology” This study suggests that combining baricitinib with narrowband UV-B therapy is an effective and well-tolerated approach for treating active nonsegmental vitiligo.
1 citations
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February 2023 in “Pharmaceutics” This article reviews cell proteomic footprinting technology and its application in improving the authentication and quality control of cell-based immunotherapeutics, without providing new clinical results.
November 2022 in “The journal of investigative dermatology/Journal of investigative dermatology” This study found that conditional deletion of CD271 in mouse epidermis led to significant disorganization and increased thickness, suggesting CD271's crucial role in regulating skin differentiation and structure.
19 citations
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May 2020 in “Cells” This study found that 5% primed conditioned medium from human umbilical cord blood-derived mesenchymal stromal cells significantly improved hair density, thickness, and growth rate in patients with androgenetic alopecia.
December 2025 in “Actas Dermo-Sifiliográficas” Bicalutamide may improve hair growth in postmenopausal women with mild side effects.
35 citations
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September 2009 in “Development” This study found that overexpression of the intercellular adhesion protein Necl2 in hair follicle stem cells was associated with reduced cell proliferation and delayed wound healing in both cultured cells and transgenic mice.
July 2024 in “Journal of Investigative Dermatology” CRISPR/Cas9 and prime editing can potentially fix skin disorder genes safely and effectively.
9 citations
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August 2002 in “British journal of ophthalmology” This case report describes a young man diagnosed with encephalocraniocutaneous lipomatosis who had unique bilateral optic disc colobomas, a previously unreported association with this syndrome.
January 2026 in “Cosmetics” This study reported that Cacumen Platycladi extract significantly reduced hair loss and increased hair density in a 12-week clinical trial, suggesting it may be a safe and effective natural treatment.
This study mapped potential targets and pathways for baicalin's action in androgenic alopecia, suggesting it may inhibit 5α-reductase and serve as an effective treatment ingredient.
July 2024 in “Journal of Investigative Dermatology” This study identified CXXC5 as a key mediator of hair loss induced by PGD2 and DHT via suppression of the Wnt/β-catenin pathway, with implications for potential therapeutic targets.
January 2010 in “Journal of Oriental Medicine” This study found that Phellodendri Cortex Ex may reduce prostate tissue damage and inhibit $5{\alpha}$-reductase gene expression in a rat model of benign prostatic hyperplasia, suggesting potential therapeutic benefits.
7 citations
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March 2023 in “Lasers in Surgery and Medicine” This study found that a single ablative fractional laser treatment significantly reduced hedgehog pathway gene expression in microscopic murine basal cell carcinomas, nearly matching the effects of repeated topical vismodegib applications.
3 citations
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June 2013 in “Genes & development” In their research, Yucel and colleagues found that CaV1.2 is expressed in hair follicle stem cells, facilitating anagen re-entry in a way not dependent on calcium flux.
June 2017 in “DOAJ (DOAJ: Directory of Open Access Journals)” This study found that finasteride's solubility and bioavailability were improved when using a dimethyl-β-cyclodextrin inclusion complex compared to the drug alone.
April 2023 in “The journal of investigative dermatology/Journal of investigative dermatology” In this study, a single subcutaneous dose of PTH-CBD showed similar hair regrowth to daily oral ruxolitinib in mice with alopecia, possibly through increased beta-catenin and anagen transition stimulation.
September 2022 in “PubMed” Entadfi, a mix of finasteride and tadalafil, is used for BPH.
44 citations
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May 2023 in “MedComm” This review highlights the potential of PROTAC technology in drug discovery for previously undruggable targets, particularly in cancer therapy, while emphasizing the urgent need to discover more E3 ligase recruiters to optimize targeted protein degradation.
33 citations
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January 1997 in “Journal of Investigative Dermatology” Interleukin-1β stops hair growth by increasing cyclic AMP levels.
January 2026 in “Asian Journal of Pharmaceutical and Clinical Research” This review discusses the potential of umbilical cord blood and umbilical cord-derived stem cells in treating various chronic diseases by highlighting their regenerative abilities and ethical advantages as well as the translational challenges and clinical implications.
7 citations
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March 2022 in “International Journal of Molecular Sciences” This study found that FGF21 suppresses inflammation induced by C. acnes in both human skin cells and mouse models, suggesting potential use in acne treatment.
October 2018 in “International journal of clinical & experimental dermatology” In this pilot study, baicalin-containing serum significantly decreased hair loss and increased hair growth after two months in participants with telogen effluvium, as subjective and objective assessments showed statistically significant improvements in hair thickness and density.
55 citations
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June 2014 in “Nature Communications” This study found that overexpression of the transcription factor Tcf3 accelerates keratinocyte migration and skin wound healing in mice, highlighting its potential as a therapeutic target for wound repair.