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![The anti‐apoptotic Bcl‐2 protein regulates hair follicle stem cell function](/images/research/3cd23f20-6ac2-46ac-9d5f-4047a363d57e/small/19231.jpg)
research The anti‐apoptotic Bcl‐2 protein regulates hair follicle stem cell function
The Bcl-2 protein is important for keeping hair follicle stem cells working and preventing hair loss.
![Mesenchymal Stromal Cell-Conditioned Medium for Skin Diseases: A Systematic Review](/images/research/6767f9e8-43d9-48b9-890c-c9226aae9c32/small/21420.jpg)
research Mesenchymal Stromal Cell-Conditioned Medium for Skin Diseases: A Systematic Review
The review suggests that a special cell-derived treatment shows promise for various skin conditions and hair growth but needs more research for confirmation.
research Teratogenic effect of isotretinoin in both fertile females and males (Review)
Isotretinoin can cause serious birth defects and needs careful use, especially in pregnant women.
![Metformin and Malignant Tumors: Not Over the Hill](/images/research/a143a81c-c4df-493b-b276-62c520c1af92/small/22851.jpg)
research Metformin and Malignant Tumors: Not Over the Hill
Metformin, a diabetes drug, may help prevent and treat various cancers, but more research is needed.
![Hair follicle-derived mesenchymal stem cells decrease alopecia areata mouse hair loss and reduce inflammation around the hair follicle](/images/research/eff0d3b8-aba7-4a72-8f9a-2474cec7db56/small/17098.jpg)
research Hair follicle-derived mesenchymal stem cells decrease alopecia areata mouse hair loss and reduce inflammation around the hair follicle
Hair follicle stem cells reduced hair loss and inflammation in mice with a condition similar to human alopecia.
![Network-Based Approaches Reveal Potential Therapeutic Targets for Host-Directed Antileishmanial Therapy Driving Drug Repurposing](/images/research/52df65f2-0e7e-4f7b-9818-9d3e61a75f25/small/17089.jpg)
research Network-Based Approaches Reveal Potential Therapeutic Targets for Host-Directed Antileishmanial Therapy Driving Drug Repurposing
Researchers identified five new potential targets for leishmaniasis treatment, suggesting repurposing existing drugs could be effective.
![Application of Ethanol Extracts From Alnus sibirica Fisch. ex Turcz in Hair Growth Promotion](/images/research/e223613e-f6db-40f3-b0ce-9d7ce16cf7c3/small/20148.jpg)
research Application of Ethanol Extracts From Alnus sibirica Fisch. ex Turcz in Hair Growth Promotion
Extracts from Alnus sibirica and oregonin may help with hair growth and prevent hair loss.
![Chemokine C-C Motif Ligand 7 (CCL7), a Biomarker of Atherosclerosis, Is Associated with the Severity of Alopecia Areata: A Preliminary Study](/images/research/c4326394-9b1b-41ae-bee2-18e0f72b6bed/small/17070.jpg)
research Chemokine C-C Motif Ligand 7 (CCL7), a Biomarker of Atherosclerosis, Is Associated with the Severity of Alopecia Areata: A Preliminary Study
Higher levels of CCL7 are linked to more severe hair loss in alopecia areata patients.
research Repigmentation by combined narrow‑band ultraviolet B/adipose‑derived stem cell transplantation in the mouse model: Role of Nrf2/HO‑1‑mediated Ca2+ homeostasis
Combining narrow-band ultraviolet B light and stem cell transplantation helps repigmentation in vitiligo by maintaining calcium balance in mice.
![The Combined Use of Platelet-Rich Plasma and Adipose-Derived Mesenchymal Stem Cells Promotes Healing. A Review of Experimental Models and Future Perspectives](/images/research/fc734728-1beb-474e-b4ff-6b343c763eaa/small/13204.jpg)
research The Combined Use of Platelet-Rich Plasma and Adipose-Derived Mesenchymal Stem Cells Promotes Healing. A Review of Experimental Models and Future Perspectives
Using Platelet-Rich Plasma and Adipose-Derived Mesenchymal Stem Cells together can improve healing, including wound healing, bone regeneration, and hair growth.
![A Systematic Review of Antiaging Effects of 23 Traditional Chinese Medicines](/images/research/dfa79068-71ef-43b3-bf6a-f34e26b1b0e6/small/17213.jpg)
research A Systematic Review of Antiaging Effects of 23 Traditional Chinese Medicines
Some traditional Chinese medicines may have anti-aging benefits and could help with hair growth, but more research is needed.
research Beyond Expectations
Keratin proteins are crucial for healthy skin, but mutations can cause skin disorders with no effective treatments yet.
![Endocrine systems of the skin](/images/research/80dc4718-1251-43dd-a5ae-d45b99166131/small/20915.jpg)
research Endocrine systems of the skin
The skin acts like an endocrine organ, making hormones that affect skin diseases and respond to stress.
![Reversing Gray Hair: Inspiring the Development of New Therapies Through Research on Hair Pigmentation and Repigmentation Progress](/images/research/6ad0bdff-5107-4714-ae8f-fb35d3a0d970/small/36957.jpg)
research Reversing Gray Hair: Inspiring the Development of New Therapies Through Research on Hair Pigmentation and Repigmentation Progress
Gray hair can potentially be reversed, leading to new treatments.
![Introduction to Transplantology](/images/research/dd5879c3-7279-41e1-8c2e-2e0f5e763e5d/small/21530.jpg)
research Introduction to Transplantology
The document concludes that transplantology has evolved with improved techniques and materials, making transplants more successful and expanding the types of transplants possible.
![Hair Physiology (Hair Growth, Alopecia, Scalp Treatment, etc.)](/images/research/bf1aba3e-e631-4ba7-96b5-a1f81e6a20ff/small/16055.jpg)
research Hair Physiology (Hair Growth, Alopecia, Scalp Treatment, etc.)
The document concludes that new treatments for hair loss may involve a combination of cosmetics, clinical methods, and genetic approaches.
![COX2-ATP Synthase Regulates Spine Follicle Size in Hedgehogs](/images/research/b3506cad-19c3-43b3-aaee-02e26c098268/small/37008.jpg)
research COX2-ATP Synthase Regulates Spine Follicle Size in Hedgehogs
COX2 and ATP synthase control the size of hedgehog spines.
![Phytochemicals as emerging therapeutic agents for alopecia treatment](/images/research/80408b69-94c8-496f-8e48-f37f88bfd46c/small/12108.jpg)
research Phytochemicals as emerging therapeutic agents for alopecia treatment
Plant-based chemicals may help hair growth and prevent hair loss but need more research to compete with current treatments.
![Aging and Anti-Aging in Hair and Hair Loss](/images/research/0f8dd8d0-9091-49d3-a36c-e182452f2a47/small/18925.jpg)
research Aging and Anti-Aging in Hair and Hair Loss
Hair ages and thins due to factors like inflammation and stress, and treatments like antioxidants and hormones might improve hair health.
![The AR/miR-221/IGF-1 pathway mediates the pathogenesis of androgenetic alopecia](/images/research/7bcbe5b4-8a67-4d80-81f8-5f56cd0abbf0/small/16766.jpg)
research The AR/miR-221/IGF-1 pathway mediates the pathogenesis of androgenetic alopecia
A specific pathway involving AR, miR-221, and IGF-1 plays a key role in causing common hair loss.
![Curcumin-zinc framework encapsulated microneedle patch for promoting hair growth](/images/research/0b1875ef-54fe-4bc8-9a8d-7807cc0f9505/small/12933.jpg)
research Curcumin-zinc framework encapsulated microneedle patch for promoting hair growth
A patch with curcumin-zinc can improve hair growth and health by delivering beneficial particles to the skin, increasing hair follicles, and reversing effects of a hair loss hormone.
![Pathogenesis of Hand-Foot Syndrome induced by PEG-modified liposomal Doxorubicin](/images/research/0e6fd0c1-da99-4f10-bad8-1a58664a40dd/small/36531.jpg)
research Pathogenesis of Hand-Foot Syndrome induced by PEG-modified liposomal Doxorubicin
PEGL-DOX causes Hand-Foot Syndrome due to skin reactions from prolonged circulation and ROS generation.
![Zinc as an ambivalent but potent modulator of murine hair growth in vivo- preliminary observations](/images/research/08ef93cf-d690-4a97-a679-ac68d2ec61ce/small/24972.jpg)
research Zinc as an ambivalent but potent modulator of murine hair growth in vivo- preliminary observations
Zinc can both inhibit and stimulate mouse hair growth, and might help recover hair after chemotherapy.
![Steroidal 5α-reductase and 17α-hydroxylase/17,20-lyase (CYP17) inhibitors useful in the treatment of prostatic diseases](/images/research/d8ce08f7-330c-47b2-83cc-7f1f5be83619/small/14505.jpg)
research Steroidal 5α-reductase and 17α-hydroxylase/17,20-lyase (CYP17) inhibitors useful in the treatment of prostatic diseases
Certain drugs that block specific enzymes can help treat prostate diseases.
![Targeted Disruption of Stat3 Reveals a Major Role for Follicular Stem Cells in Skin Tumor Initiation](/images/research/ccf79a97-3fd4-4348-82cb-043079cd033f/small/36206.jpg)
research Targeted Disruption of Stat3 Reveals a Major Role for Follicular Stem Cells in Skin Tumor Initiation
Disrupting Stat3 in hair follicle stem cells greatly reduces skin tumor formation.
![MOF-mediated Histone H4 Lysine 16 Acetylation Governs Mitochondrial and Ciliary Functions By Controlling Gene Promoters](/images/research/4d4e031e-b601-45e5-8dec-ae309d66cc83/small/36772.jpg)
research MOF-mediated Histone H4 Lysine 16 Acetylation Governs Mitochondrial and Ciliary Functions By Controlling Gene Promoters
MOF controls skin development by regulating genes for mitochondria and cilia.
![The non-neuronal and nonmuscular effects of botulinum toxin: an opportunity for a deadly molecule to treat disease in the skin and beyond](/images/research/7b1278ca-86ce-494d-8259-1a9df0c9a1cc/small/17986.jpg)
research The non-neuronal and nonmuscular effects of botulinum toxin: an opportunity for a deadly molecule to treat disease in the skin and beyond
Botulinum toxin has potential for treating various skin conditions and improving wound healing.
![Consensus on the use of oral isotretinoin in dermatology - Brazilian Society of Dermatology](/images/research/8ad911fb-de04-4ffa-b637-c04c3a99e686/small/23900.jpg)
research Consensus on the use of oral isotretinoin in dermatology - Brazilian Society of Dermatology
The Brazilian Society of Dermatology agrees that oral isotretinoin is effective for acne and other skin conditions, and it's safe when monitored, but more research is needed on dosing and duration.