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Cell polarity signaling controls tissue mechanics and cell fate, with complex interactions and varying pathways across species.

Excessive eyelash growth from erlotinib may indicate positive tumor response and help treat madarosis.

Disrupting the Flcn gene in mice causes early kidney cysts and tumors, which can be treated with rapamycin.

In vivo lineage labelling is better than in vitro methods for identifying and understanding stem cells.

Overexpressing SSAT enzyme reduces prostate tumor growth in mice.

Hedgehog pathway inhibitors can treat certain aggressive cancers but face limitations like resistance and side effects.

Mesenchymal Stem/Stromal Cells (MSCs) help in wound healing and tissue regeneration, but can also contribute to tumor growth. They show promise in treating chronic wounds and certain burns, but their full healing mechanisms and potential challenges need further exploration.

YAP and TAZ are crucial for skin cell growth and repair.

Wnt10b helps blood stem cells grow after injury.

Different types of skin fibroblasts have unique roles in skin health and disease.

The document concludes that there is a need for more research and regulation in dermatology, covering topics like latex allergy in children, the use of botulinum toxin, and treatments for skin conditions.

The conclusion suggests that prostate cancer should be classified by castration status and that new therapies targeting androgen receptor signaling show promise.

Prostate cancer cells can make their own androgens to activate the androgen receptor, and treatments like abiraterone may increase this ability, suggesting new therapies should target the entire steroid-making pathway.

Stem cell plasticity is crucial for wound healing but can also contribute to cancer development.

Prostate cancer prevention includes diet changes, supplements, and medications, with more answers expected soon.

Low zinc levels may be linked to the return of gynecologic cancers.

A cancer patient developed a type of hair loss after starting a cancer drug called vandetanib.

PCOS may increase the risk of certain cancers.

Understanding where cancer cells come from helps create better prevention and treatment methods.

Men, especially older ones with health issues like prostate cancer, may have worse COVID-19 outcomes and could benefit from therapies targeting male hormones.

The document concludes that targeting the androgen receptor may be a promising breast cancer treatment, especially for certain types.

Steroid sex hormones activate matriptase in prostate cancer cells but not in breast cancer cells.

Men taking 5-alpha-reductase inhibitors before or after bladder cancer diagnosis had a lower risk of dying from the disease.

Men with male pattern baldness have a higher risk of dying from prostate cancer.

Higher DHT in male baldness may protect against prostate cancer.

Baldness, especially at the front, may lower the risk of testicular cancer by 31%, but its link to prostate cancer is unclear.

A group has developed therapies that show promise for treating cancer and various other conditions.

Eating more omega-3 and less omega-6 fatty acids may lower the risk of developing prostate cancer.

Keratins help protect cells, aid in cancer diagnosis, and influence cancer behavior and treatment.

African American men with prostate cancer have more androgen receptor mutations, which may lead to more aggressive cancer compared to Caucasian American men.