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This review discusses plant-derived phytochemicals, such as phytosterols, polyphenols, and fatty acids, as potential alternatives to 5-alpha-reductase inhibitors for prostate cancer treatment, highlighting their promising anti-cancer properties and potentially fewer side effects compared to conventional drugs.

This review discusses the diverse industrial applications of hemp beyond traditional fiber uses, highlighting its phytochemical components with antioxidant and antimicrobial properties that are explored in agrochemicals, cosmetics, and food sectors.

This review examines recent advances in androgenetic alopecia treatment, highlighting how multifunctional plant extracts combined with nanotechnology could improve topical therapy efficacy by enhancing local drug bioavailability and targeting, addressing limitations of existing treatments.

In this study, six types of cold-pressed oils commonly found in the Polish market were analyzed for their health-promoting compounds and antioxidant activity, revealing them as valuable sources of bioactive compounds like polyunsaturated fatty acids, tocopherols, sterols, and polyphenols, without exceeding recommended deterioration parameters.

This review concluded that the efficacy of cosmeceutical hair serums for addressing hair loss lies in their use of bioactive peptides and plant compounds, like flavonoids and sterols, that target eight key contributing factors identified in hair loss conditions.

This review highlights the potential of plant-derived natural compounds as biocompatible and biodegradable materials in dermal and transdermal delivery systems, emphasizing their unexplored benefits and detailing recent advances in isolation techniques and drug delivery technologies.

This review discusses the biologically active compounds in Maxillariinae orchids, highlighting 62 semiochemicals with medical potential, but reports no new clinical findings.

This study identified two potent 5α-reductase inhibitors from Tectona grandis leaves, and suggests that ethanol is a preferable solvent for extracting these compounds, which are potential ingredients for hair loss treatments.

This literature review reported limited and low-quality studies on Serenoa repens for androgenetic alopecia, suggesting it may be effective but less so than finasteride, and highlighted the need for better-designed research to confirm its utility.

This review discusses the potential of phytochemicals from plants as alternative treatments for prostate cancer, highlighting their possible benefits over current 5-alpha-Reductase inhibitors, but reports no new findings.

This review explores plant-derived phytochemicals, such as phytosterols, polyphenols, and fatty acids, for their potential use as alternative treatments for prostate cancer, emphasizing their effects on 5-alpha-Reductase enzyme isozymes. It reports no new clinical results.

This study reports that using ascorbic acid or orlistat can significantly inhibit the metabolism of testosterone esters into malodorous metabolites by axillary bacteria, suggesting potential new deodorant applications.

The study found that cyproterone acetate could be released over 15 days using coconut oil mixed with certain wax inhibitors, though further safety studies are needed.

This study found that curcumin may improve glycemic control and lipid metabolism in patients with PCOS, although its effects on low-density lipoprotein and triglycerides were not significant.

This review discusses testosterone replacement therapy, highlighting that most studies report no increased myocardial infarction risk when the therapy is properly administered with controlled hormone levels; it calls for careful consideration despite insurance coverage challenges.

This study found that fermented camel milk containing 50% pumpkin seed milk significantly improved oxidative stress markers in rats and enhanced sensory and physicochemical properties compared to untreated groups.

The researchers concluded that after the 2013 EMA recommendation, there was an overall reduction in CPA/EE prescriptions, but no substantial change in patient diagnoses or potential concurrent hormonal contraceptive use.

This research investigated the design and synthesis of steroid-based compounds as aromatase inhibitors for breast cancer, finding that certain structural modifications significantly enhance their inhibitory potency.

This study investigated the effects of Christia vespertilionis extract on breast cancer cell lines, finding that it had a concentration-dependent cytotoxic effect, although less potent than tamoxifen, suggesting potential as an alternative cancer treatment.

This study suggests that dietary decanoic acid may manage hyperandrogenism and insulin resistance in PCOS, as observed in animal and cell model experiments.

This report suggests that TCDD may alter human epidermal stem cell populations by upregulating c-Myc, potentially leading to increased stem cell turnover during chloracne development.

This article reviews the use of anti-androgens, particularly cyproterone acetate, for managing hirsutism, but does not provide new clinical results.

Long-term use of canthaxanthin may cause reversible changes in the eye, including crystal deposits and altered vision responses.

This study found that steroid hormone treatments significantly reduced mRNA expression of certain Ca2+-activated K+ channel genes in Atlantic cod pituitary cells, suggesting a potential role in sexual maturation regulation.

This study observed that PCE-DP may improve skin pigmentation by increasing epidermal turnover and inhibiting melanin uptake and inflammation in human epidermal keratinocytes.

This case report describes a 73-year-old male with numerous colon polyps whose long-term use of Cape Aloe likely caused melanosis coli, which helped highlight the polyps' locations.

This study found that abietic acid from pine resin more effectively inhibits testosterone 5α-reductase than several plant extracts, suggesting potential for treating androgen-dependent diseases.

This study found that adrenal sex hormone levels were elevated in neutered dogs with hypercortisolemia, except for testosterone, highlighting the importance of ruling out hypercortisolemia when diagnosing adrenal hyperplasia syndrome.

This study reported that methanolic extracts from marine sponges, particularly Petrosia sp. and Agelas nakamurai, showed significant enzyme inhibitory activities, with Petrosia sp. exhibiting notable 5?-reductase inhibition.

Clascoterone safely promotes hair growth similar to minoxidil.