26 citations,
April 1977 in “PubMed” Minoxidil, a blood pressure drug, can cause excessive hair growth, but this can be successfully treated with a hair removal agent called calcium thioglycolate.
August 1994 in “Molecular Endocrinology” Changing protein kinase levels in pituitary cells affects calcium flow and beta-endorphin release.
[object Object] 47 citations,
October 1989 in “Circulation Research” The study explains how minoxidil sulfate causes vasodilation in rabbits by opening potassium channels and inhibiting calcium channels.
25 citations,
May 2020 in “EMBO reports” Calcium is important for stem cell function and maintenance, especially in blood and skin cells.
25 citations,
August 2014 in “Endocrinology” Researchers created a mouse model of a type of rickets that does not cause hair loss.
185 citations,
December 2011 in “Molecular and cellular endocrinology” Skin cells produce and activate vitamin D, which regulates skin functions and supports hair growth.
31 citations,
December 2002 in “Biochimica et biophysica acta. G, General subjects/Biochimica et biophysica acta. General subjects (Online)” The research found two types of calcium in human hair, one that varies among individuals and another that is consistent across people.
11 citations,
January 2011 in “Turkish Journal of Medical Sciences” Low iron levels are a significant risk factor for hair loss, while high vitamin D levels might be a response to hair loss, not a cause.
6 citations,
June 2018 in “Journal of pediatric endocrinology & metabolism/Journal of pediatric endocrinology and metabolism” Patients with the same genetic mutation for vitamin D-resistant rickets showed different symptoms but all improved with treatment except for hair loss.
104 citations,
May 2003 in “Endocrinology” Lampreys have a functional vitamin D receptor that may help detoxify harmful substances.
81 citations,
January 2006 in “Journal of cellular physiology” Mice without the vitamin D receptor gene lose hair due to disrupted hair follicle cycles.
31 citations,
January 2007 in “Journal of biological chemistry/The Journal of biological chemistry” Stress activates a special function of the Vitamin D receptor with the help of c-Jun, which can also prevent cell death.
29 citations,
December 2017 in “International Journal of Dermatology” People with alopecia areata often have lower vitamin D levels, which are linked to more severe and longer-lasting hair loss, but vitamin D receptor levels in the skin don't show the same pattern and don't predict treatment success.
28 citations,
January 2012 in “Biological & pharmaceutical bulletin” Hairless protein can both repress and activate vitamin D receptor functions, affecting gene regulation.
20 citations,
May 2016 in “Journal of Cosmetic Dermatology” Low vitamin D receptor levels found in hair loss patients; topical vitamin D treatment suggested.
8 citations,
June 2020 in “International Journal of Dermatology” Men with early hair loss have lower vitamin D levels.
7 citations,
October 2019 in “Clinical, Cosmetic and Investigational Dermatology” Certain gene variations in the Vitamin D receptor may increase the risk of chronic hair loss.
5 citations,
January 1970 in “Journal of Nepal Paediatric Society” Hair loss can be a key sign of a rare type of rickets when vitamin D treatment doesn't work and advanced tests aren't available.
3 citations,
March 2019 in “Fayoum University Medical Journal/Fayoum University Medical Journal ” Rubbing calcipotriol on the skin works better than taking vitamin D pills for treating mild to moderate alopecia areata.
2 citations,
January 2019 in “International journal of medicine in developing countries” Many people in Majmaah city, Saudi Arabia, don't know much about vitamin D deficiency and don't practice good vitamin D habits, with few linking it to hair loss.
April 2024 in “Nepal journal of dermatology, venereology & leprology” Vitamin D is important for skin health and can help treat and prevent various skin conditions.
February 2022 in “Global academic journal of medical sciences” People with alopecia areata have much lower Vitamin-D levels than healthy individuals.
January 2019 in “Clinical neuropharmacology” A girl's hair-pulling condition improved greatly after she started vitamin D treatment.
September 2018 in “International Journal of Dermatology” People with alopecia areata often have lower levels of zinc and vitamin D.
February 2018 in “Egyptian Journal of Radiation Sciences and Applications” Patients with Discoid Lupus Erythematosus have lower vitamin D and antioxidant levels and higher oxidative stress.
April 2017 in “Journal of nutritional health & food engineering” Over 65% of people in the United Arab Emirates have undetected vitamin D deficiency, causing symptoms often mistaken for stress or migraines.
200 citations,
November 1997 in “Planta” Calcium affects where root hairs grow, but other unknown factors determine their growth direction.
72 citations,
June 2001 in “Journal of Investigative Dermatology” S100A4 and S100A6 proteins may activate stem cells for hair follicle regeneration and could be potential targets for hair loss treatments.
62 citations,
January 2013 in “Skin Pharmacology and Physiology” Low iron and vitamin D levels are linked to hair loss in women.
[object Object] 57 citations,
April 2002 in “The journal of investigative dermatology/Journal of investigative dermatology” Vitamin D receptor is crucial for starting hair growth after birth.