research A Model for the Turnover of Dihydrotestosterone in the Presence of the Irreversible 5α-Reductase Inhibitors GI198745 and Finasteride
Both drugs lower DHT levels, with GI198745 being more effective.
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research Polycystic Ovary Syndrome (PCOS) – An Overview
PCOS is a hormonal disorder causing symptoms like irregular periods and acne, and increases the risk of diabetes and heart disease.
research Dutasteride Reduces Alcohol’s Sedative Effects in Men in a Human Laboratory Setting and Reduces Drinking in the Natural Environment
Dutasteride makes alcohol less sedating and may lead to less drinking in men.
research Adverse Side Effects of 5α-Reductase Inhibitors Therapy: Persistent Diminished Libido, Erectile Dysfunction, and Depression in a Subset of Patients
Some patients taking finasteride or dutasteride may have ongoing sexual problems and depression even after stopping the medication.
research The VEGF +405 G>C 5' Untranslated Region Polymorphism and Risk of PCOS: A Study in South Indian Women
The VEGF +405G allele may increase the risk of PCOS in South Indian women.
research A Review on Change in Chemical, Morphological, and Therapeutic Activity of Honey
Honey has many health benefits and is good for you.
research High Resolution Full Scan Liquid Chromatography Mass Spectrometry Comprehensive Screening in Sports Antidoping Urine Analysis
The method effectively detects banned substances in urine for sports antidoping.
research Autophagy Induces Hair Follicle Stem Cell Activation and Hair Follicle Regeneration by Regulating Glycolysis
Autophagy helps activate hair stem cells and hair growth by changing their energy use to glycolysis.
research An Innovation in Suction Assisted Follicular Unit Extraction
The new FUE device improves hair transplant safety and efficiency.
research Azathioprine
Azathioprine's effectiveness and safety require careful monitoring and more research, especially regarding its use with corticosteroids and the role of TPMT status in patients.
research Olfactory Receptor OR2AT4 Regulates Human Hair Growth
A certain smell receptor in hair follicles can affect hair growth when activated by a synthetic sandalwood scent.
research Apocrine Sweat Gland Obstruction by Antiperspirants Allowing Transdermal Absorption of Cutaneous Generated Hormones and Pheromones as a Link to the Observed Incidence Rates of Breast and Prostate Cancer in the 20th Century
The document suggests that blocking sweat glands with antiperspirants might allow skin-generated hormones to be absorbed, possibly increasing breast and prostate cancer risk.
research Pharma in the Bedroom and the Kitchen: The Pharmaceuticalisation of Daily Life
The conclusion is that the increasing use of drugs for lifestyle reasons is a complex issue influenced by corporate profit, consumer behavior, and the medicalization of everyday life, with potential negative effects on personal well-being.
research Aging and Immortality: Quasi-Programmed Senescence and Its Pharmacologic Inhibition
The conclusion is that using drugs to block the TOR pathway might slow aging and prevent age-related diseases.
research GWAS for Male-Pattern Baldness Identifies 71 Susceptibility Loci Explaining 38% of the Risk
Researchers found 71 genetic regions linked to male pattern baldness, which account for 38% of its genetic risk.
research Refinement of Technique in Injection Lipolysis Based on Scientific Studies and Clinical Evaluation
Injection lipolysis effectively reduces small fat deposits and should be done with care and proper patient selection.
research Preparation and Characterization of Beta-Sitosterol-Loaded Nanostructured Lipid Carriers for Butter Enrichment
Researchers made a special butter with added betasitosterol that could be healthier for the heart and stayed good for three months.
research Hormones
Hormones are crucial for regulating body functions and imbalances can lead to health issues.
research Pharmacokinetic Interaction of Finasteride With Tamsulosin Hydrochloride: An Open-Label, Randomized, Three-Period Crossover Study in Healthy Chinese Male Volunteers
Finasteride and tamsulosin hydrochloride can be safely taken together without significant interaction.
research Pregnancy Outcomes with Paternal Exposure to Finasteride, a Synthetic 5-Alpha-Reductase Inhibitor: A Case Series
Babies were mostly born healthy from fathers who took finasteride, but some pregnancies ended early; more research is needed.
research Mesotherapy
Mesotherapy is a minimally invasive treatment with potential benefits and risks, requiring standardized practices and further investigation.
research Fetal Alcohol Syndrome: Current Status of Pathogenesis
The document concludes that the exact way alcohol causes harm to fetal development is unknown, but it significantly affects nutrient transport to the fetus and a safe level of alcohol during pregnancy is not determined.
research Evaluation of Sleep Quality, Restless Legs Syndrome, Anxiety, and Depression in Polycystic Ovary Syndrome
People with polycystic ovary syndrome are more likely to have poor sleep, restless legs syndrome, anxiety, and depression.
research Stable Isotope Analyses of Carbon and Nitrogen in Hair Keratin of Suspected Man-Eating Wolves from the 1880s
The wolves suspected of man-eating in the 1880s likely ate very little human flesh and mostly consumed a diet similar to herbivores and omnivores.
research Neurosteroids, Neuroactive Steroids, and Symptoms of Affective Disorders
Certain steroids in the brain affect mood and symptoms of depression, and treatments targeting these steroids show promise for improving these symptoms.
research Effects of Hair Dying by Used-Up Coffee Grounds Extract
research Research on Mental Stress Recognition of Depressive Disorders in Patients with Androgenic Alopecia Based on Machine Learning and Fuzzy K-Means Clustering
The FAW-FS algorithm improves depression recognition, and psychological interventions help AGA patients' mental health.
research Teriflunomide in Patients with Relapsing-Remitting Forms of Multiple Sclerosis
Teriflunomide is effective and generally safe for treating relapsing-remitting multiple sclerosis.
research In Silico Study on the Contribution of the Follicular Route to Dermal Permeability of Small Molecules
Hair follicles affect how well small molecules can pass through the skin, and this varies depending on the molecule's features.
research Study on Knowledge of Chemotherapy's Adverse Effects and Their Self-Care Ability to Manage - The Cancer Survivors Impact
Better awareness of chemotherapy's side effects improves self-care.