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Type 3 5α-reductase is more common and finasteride and dutasteride strongly inhibit it.

The S100A4 protein is more common in psoriatic skin and could be a target for treating psoriasis.

Inhibitors of 11β-HSD1 show potential for treating type 2 diabetes but require more testing for safety and effectiveness.

A gene variant in KRT71 causes the curly fur in Selkirk Rex cats.

A gene in Arabidopsis thaliana, AtPRPL1, affects root hair length but not cell wall composition.

A new skin-whitening agent using a peptide from wheat is safe and effective at reducing skin pigmentation.

Two distinct pathways direct proteins to vacuoles in Arabidopsis, affecting root hair growth and protein targeting.

Activating Notch in adult skin causes T cells and neural crest cells to gather, leading to skin issues.

ROOT HAIR SPECIFIC 10 (RHS10) reduces the length of root hairs in Arabidopsis plants.

Enzyme replacement therapy improved multiple symptoms of homocystinuria in mice.

3D-printed mesoporous scaffolds show promise for personalized drug delivery with controlled release.

Thymosin β4 helps improve skin healing and reduce scarring.

Hairless protein can both repress and activate vitamin D receptor functions, affecting gene regulation.

PDI helps restore over-bleached hair's strength and structure by attaching special peptides.

Certain essential oils can activate a human skin receptor, potentially helping with skin disorders.

Sp6 promotes tooth development by reducing follistatin levels.

Minoxidil protects heart and improves recovery.

The study found that variations in hair protein genes are likely due to evolutionary deletions or duplications.

Minoxidil reduces lysine hydroxylase in skin cells.

The document concludes that certain mutations may contribute to the inflammation in hidradenitis suppurativa and suggests that targeting TNFα could be a treatment strategy.

R-spondins and their receptors help increase bone growth and may be used to treat bone loss diseases.

Some growth factors, while important for normal body functions, can cause diseases when not regulated properly.

The hair keratin gene KRT81 is found in both normal and breast cancer cells and helps them invade surrounding tissues.

Steroid sulfatase is important for activating hormones that affect memory, brain function, and certain diseases, and could be a target for treating hormone-related disorders.

Interferons are effective for some skin conditions and cancers, but can have side effects and need more research for optimal use.

The protein CCN2 controls hair growth by affecting hair follicle formation and stem cell activity in mice.

Minoxidil may help prevent capsular opacification after cataract surgery.

Non-immune factors play a significant role in alopecia areata.

The research suggests that the ZP4 gene is linked to egg development in women with PCOS but requires more study to understand its role in infertility.

The G60S Connexin43 mutation causes hair growth issues and poor hair quality in mice, similar to human ODDD patients.