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      WNT Signaling in Disease

      research WNT Signaling in Disease

      144 citations , August 2019 in “Cells”
      This review discusses the WNT signaling pathway's involvement in human diseases and highlights recent advances in WNT-related treatments, but it presents no new research findings.
      K ATP Channels and Cardiovascular Disease

      research K ATP Channels and Cardiovascular Disease

      144 citations , March 2013 in “Circulation Research”
      This study reports that mutations in the SUR2 gene are linked to Cantu syndrome, highlighting the role of KATP channels in cardiovascular health and potential new therapies.
      Molecular Mechanisms of Viral Oncogenesis in Humans

      research Molecular mechanisms of viral oncogenesis in humans

      141 citations , August 2018 in “Nature Reviews Microbiology”
      This review discusses the molecular mechanisms by which oncogenic viruses contribute to cancer development through manipulation of host cellular functions and highlights the need for further research into virus-associated cancers, reporting no new results.
      Protoporphyrin IX: The Good, the Bad, and the Ugly

      research Protoporphyrin IX: the Good, the Bad, and the Ugly

      138 citations , November 2015 in “Journal of Pharmacology and Experimental Therapeutics”
      This review discusses the mechanisms associated with protoporphyrin IX in living cells and reports no clinical results; the authors emphasize its potential in cancer diagnosis and the risks of toxicity.
      EEMCO Guidance for the In Vivo Assessment of Skin Greasiness

      research EEMCO Guidance for the in vivo Assessment of Skin Greasiness

      137 citations , January 2000 in “Skin Pharmacology and Physiology”
      This review outlines the factors affecting skin greasiness and sebum production, highlighting measurement challenges but reports no new clinical findings; further research may guide sebosuppressive treatments for acne.
      Exosomes for Repair, Regeneration, and Rejuvenation

      research Exosomes for repair, regeneration and rejuvenation

      135 citations , December 2015 in “Expert Opinion on Biological Therapy”
      This review synthesizes recent research on exosomes, highlighting their role as key modulators in regenerative outcomes and suggesting they may offer advantages over stem cell-based therapies in process and regulation.
      TGF-β Family Signaling in Stem Cells

      research TGF-β family signaling in stem cells

      132 citations , August 2012 in “Biochimica et Biophysica Acta (BBA) - General Subjects”
      This review discusses the roles of TGF-β family signaling in regulating normal and cancer stem cells and highlights the need for further research to develop potential cancer treatments; it reports no new results.
      Medical Treatment of Liver Hydatidosis

      research Medical Treatment of Liver Hydatidosis

      126 citations , January 2001 in “World Journal of Surgery”
      This review discusses current treatment options for liver hydatidosis, noting the potential benefits and limitations of chemotherapy and highlighting the need for more clinical trials to prevent recurrent disease; it reports no new findings.
      Cell Death in the Skin: Mechanisms and Implications

      research Cell death in the skin

      120 citations , February 2009 in “Apoptosis”
      This review examines apoptotic and anti-apoptotic mechanisms in skin homeostasis and related diseases but presents no new research findings.
      Drug-Induced Skin, Nail, and Hair Disorders

      research Drug-Induced Skin, Nail and Hair Disorders

      114 citations , January 2007 in “Drug Safety”
      This review discusses various adverse drug reactions affecting the skin, hair, and nails, emphasizing the importance of recognizing and reporting these reactions but reports no new clinical findings.
      From Skin Microrelief to Wrinkles: An Area Ripe for Investigation

      research From skin microrelief to wrinkles. An area ripe for investigation

      108 citations , January 2003 in “Journal of Cosmetic Dermatology”
      This summary explains the different types of wrinkles, their causes, and their distinct microanatomical characteristics, noting that each type may respond differently to treatments.
      The Proximal Promoter of the Human Transglutaminase 3 Gene

      research The Proximal Promoter of the Human Transglutaminase 3 Gene

      105 citations , February 1996 in “Journal of biological chemistry/˜The œJournal of biological chemistry”
      In this study, sequences upstream of the TGM3 gene were found to regulate epithelial-specific gene expression in keratinocytes, suggesting potential applications in gene therapy.
      4D Polycarbonates via Stereolithography as Scaffolds for Soft Tissue Repair

      research 4D polycarbonates via stereolithography as scaffolds for soft tissue repair

      101 citations , July 2021 in “Nature Communications”
      This study reported that 4D-printed, aliphatic polycarbonate-based scaffolds supported adipose tissue engineering by allowing adipocyte infiltration and neovascularization in vivo, indicating potential for effective adipose tissue repair.
      Role of 5α-Reductase in Health and Disease

      research 9 Role of 5α-reductase in health and disease

      101 citations , April 1994 in “Baillière's clinical endocrinology and metabolism”
      This review discusses the role of 5α-reductase enzymes in androgen action and related disorders, noting that their specific inhibitory drugs show promise for conditions like benign prostatic hypertrophy; it reports no new clinical results.
      Alopecia Areata: A Comprehensive Review of Pathogenesis and Management

      research Alopecia Areata: a Comprehensive Review of Pathogenesis and Management

      99 citations , July 2017 in “Clinical Reviews in Allergy & Immunology”
      This review noted that alopecia areata is an autoimmune disease impacting hair follicles and offered insights into its complex pathogenesis involving immune responses, while highlighting ongoing research into new treatments such as Janus kinase inhibitors and other immunomodulatory drugs.
      Tinea Capitis: An Overview with Emphasis on Management

      research Tinea Capitis: An Overview with Emphasis on Management

      89 citations , May 1999 in “Pediatric Dermatology”
      This article reviews the treatment options for tinea capitis, suggesting that itraconazole, terbinafine, and fluconazole are effective and safe alternatives to griseofulvin but reports no new clinical results.