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New targets for making and using brain-synthesized steroids could lead to better treatments for brain disorders and alcoholism.

Progesterone boosts alcohol's effect on brain, finasteride counters it.

Allopregnanolone is needed for certain brain processing issues caused by D1 dopamine receptor activation.

Androgens like testosterone may help treat traumatic brain injury by reducing mitochondrial stress and inflammation.

Neuroimaging suggests that treatments targeting brain steroids could help control epilepsy, especially types linked to the menstrual cycle.

Low-dose radiation therapy may improve brain function in some Alzheimer's patients and is generally well-tolerated.

Minoxidil may help reduce aging effects in brain cells.

Finasteride can have lasting negative effects on brain function and behavior by disrupting neurosteroid production.

17α-estradiol is a safe estrogen that might protect the brain and doesn't cause feminization, needing more research for treating brain diseases.

Blocking 5α-reductase can harm memory and brain structure, and increase harmful brain changes in male mice used for Alzheimer's disease research.

Taking triterpenoids from Ganoderma lucidum over a long time can help slow down brain aging and improve overall health in mice.

Altered metabolism can help control seizures by changing brain signaling and energy use, suggesting new treatments for epilepsy.

The protein StAR is found in 17 different organs and can affect hair loss and brain functions, but its full role is not yet fully understood.

The enzymes 5α-reductase and 3α/β-hydroxysteroid oxidoreductase help create brain-active substances from progesterone and testosterone, which could be used for treatment, but more research is needed to ensure their safety and effectiveness.

TNFα, IFNγ, and Substance P significantly affect prolactin levels in human skin, suggesting new treatments for skin and hair conditions.

Brain-made chemicals can control nerve cell function differently in various parts of a mouse's brain, which may help us understand neurological conditions.

Stress can stop hair growth in mice, and treatments can reverse this effect.

The patient's long-term hair loss was caused by leukemia treatments and low estrogen levels, worsened by her genetic tendency for hair loss.

Early changes in brain chemicals affect how a drug reduces alcohol intake in rats.

The document shows the state of pharmaceutical patents as of 1999, focusing on treatments for various diseases.

Tight junctions are key for skin protection and controlling what gets absorbed or passes through the skin.

The document concludes that adenosine receptor agonists have potential for treating various conditions, but only a few are approved due to challenges like side effects and the need for selective activation.

New treatments for male hypogonadism are effective and should be personalized.

Increasing TSPO in the brain reduces anxiety and depression.

Certain brain hormones and chemicals are linked to the development of Polycystic Ovary Syndrome.

We need better ways to test and understand SARMs to make safer and more effective treatments.

A brain-made hormone can protect against memory-related brain damage caused by harmful proteins.

Anabolic steroids can build muscle and strength but have risks and need more research on their clinical benefits and side effects.

Estrogens help reduce skin aging, and SERMs might offer similar benefits without the risks of hormone therapy.

Menopause and aging can affect women's quality of life and sexuality, but hormone therapies may help alleviate these issues.