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February 2010 in “Cell Stem Cell” Stem cell niches are crucial for regulating stem cell behavior and tissue health, and their decline can impact aging and cancer.
48 citations,
July 2008 in “Acta Biochimica et Biophysica Sinica” Wnt signaling is important for development and cell regulation but can cause diseases like cancer when not working properly.
47 citations,
July 2013 in “Pharmacological Reviews” Regenerative pharmacology, which combines drugs with regenerative medicine, shows promise for repairing damaged body parts and needs more interdisciplinary research.
29 citations,
March 2012 in “Stem Cell Research & Therapy” Some stem cells in the body rarely divide, which could help create better treatments for diseases and aging.
508 citations,
February 2007 in “Cell” Epithelial stem cells are crucial for tissue renewal and repair, and understanding them could improve treatments for damage and cancer.
258 citations,
July 2016 in “Reproductive Biology and Endocrinology” The document concludes that insulin resistance is key in PCOS development and early treatment is crucial to prevent complications.
133 citations,
September 2013 in “Nature Reviews Molecular Cell Biology” Different types of stem cells and their environments are key to skin repair and maintenance.
86 citations,
July 2020 in “International Journal of Molecular Sciences” Activating the Wnt/β-catenin pathway could lead to new hair loss treatments.
66 citations,
July 2015 in “Journal of Molecular Biology” The document concludes that for hair and feather growth, it's better to target the environment around stem cells than the cells themselves.
28 citations,
March 2016 in “Toxicologic pathology” Dogs could be good models for studying human hair growth and hair loss.
19 citations,
June 2020 in “Animals” Poor maternal nutrition can lead to fewer wool follicles in Chinese Merino sheep.
1 citations,
March 2022 in “IntechOpen eBooks” Aging reduces skin stem cell function, leading to changes like hair loss and slower wound healing.
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July 2019 in “Stem Cell Research & Therapy” Epidermal stem cells help heal severe skin wounds and have potential for medical treatments.
105 citations,
October 2017 in “Stem cells” Wnt signaling is crucial for skin development and hair growth.
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August 2020 in “Genes” Different genes are active in dogs' hair growth and skin, similar to humans, which helps understand dog skin and hair diseases and can relate to human conditions.
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January 2023 in “Metabolites” Changes in gut bacteria can contribute to the development of Polycystic Ovary Syndrome (PCOS), affecting metabolism, immunity, and causing inflammation. Treatments may involve adjusting these factors.
February 2024 in “International journal of molecular sciences” Type 3 Innate Lymphoid Cells help maintain skin health and balance, and are involved in skin diseases and healing.
Certain natural products may help stimulate hair growth by affecting stem cell activity in the scalp.
10 citations,
December 2018 in “Journal of animal physiology and animal nutrition” Heat stress reduced hair growth and affected related genes in rex rabbits.
March 2023 in “Research Square (Research Square)” Immune changes and specific genes contribute to male hair loss.
28 citations,
November 2018 in “Journal of Cellular and Molecular Medicine” CXXC5 is a protein that controls cell growth and healing processes, and changes in its activity can lead to diseases like cancer and hair loss.
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July 2001 in “Cell” Cells from certain embryo parts can induce head formation in another embryo, involving complex signaling pathways.
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November 2016 in “Journal of Dental Research” Pannexin 3 is important for bone formation and the development of bone cells.
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April 2008 in “Organogenesis” Wnt signaling is crucial for skin and hair development and its disruption can cause skin tumors.
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December 2016 in “PLOS ONE” Early-stage skin cells help regenerate hair follicles, with proteins SDF1, MMP3, biglycan, and LTBP1 playing key roles.
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November 2005 in “The journal of investigative dermatology. Symposium proceedings/The Journal of investigative dermatology symposium proceedings” Hair color is determined by different melanins and changes with age.
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August 2018 in “Frontiers in Endocrinology” Androgens are important for normal ovarian function and estrogen production, but may not be the main cause of follicle death.
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December 2008 in “Laboratory investigation” Activin activation in skin cells speeds up wound healing without affecting scar quality.
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July 2021 in “Biomolecules” Centipeda minima extract helps hair grow by activating important growth signals and could be a promising hair loss treatment.