21 citations
,
May 2001 in “PubMed” This paper reviews the significance of androgen hormones in hair and skin conditions like alopecia, hirsutism, and acne, and reports no new clinical findings.
November 2015 in “International journal of science and research” This study found that adult acne is more inflammatory than adolescent acne and predominantly affects the cheeks, jaw-line, and chin.
October 2021 in “Turkderm” This study found that women with post-adolescent acne experience marked menstrual irregularities, polycystic ovaries, androgenetic alopecia, hirsutism, and metabolic syndrome, but insulin resistance and dyslipidemia may not significantly contribute to their acne's pathogenesis.
March 2026 in “IP Indian Journal of Clinical and Experimental Dermatology” This study found that female patients with acne had significantly higher insulin resistance compared to a control group without acne, suggesting that acne could serve as an early clinical marker of insulin resistance in women of reproductive age.
August 2016 in “Journal of evolution of medical and dental sciences” This study describes the clinical profile of acne vulgaris in patients from a tertiary care hospital, noting a male predominance and frequent occurrence of post acne hyperpigmentation.
33 citations
,
January 2013 in “Dermatology” This study found that among women above 15 years with acne, 54.56% exhibited hyperandrogenism, with dehydroepiandrosterone sulfate levels most frequently elevated.
30 citations
,
June 2015 in “British Journal of Dermatology” Acne is common in women, often hormone-related, negatively affects quality of life, and requires various treatments.
24 citations
,
November 2016 in “Molecular Medicine Reports” This study found that women with acne resistant to conventional treatments had significantly higher levels of testosterone, DHEA‑S, prolactin, and LH, suggesting potential underlying hormonal disorders.
November 2022 in “Journal of the Endocrine Society” This study observed improvements in hair loss, acne, and BPH symptoms after addressing vitamin D and progesterone deficiencies in male patients, suggesting the potential benefits of this therapeutic approach.
January 2018 in “Springer eBooks” This study discusses how dermatological issues in athletes can arise from or be exacerbated by mechanical trauma, infections, and environmental factors, highlighting the importance of thorough history and examination to differentiate these from other skin conditions.
24 citations
,
March 2018 in “Pediatric Dermatology” This article addresses the complexity of treating acne in female-to-male transgender adolescents undergoing testosterone therapy, highlighting concerns about co-administered treatments and their potential risks.
April 2024 in “International journal of medical science and clinical research studies” In this review, the authors examine current treatments for acne in adult women with polycystic ovarian syndrome, noting that the combination of hyperandrogenism and metabolic issues in PCOS can lead to acne formation on the face, chest, and back.
December 2024 in “Journal of Neonatal Surgery” In this study, researchers found that increased androgen levels, such as testosterone, and insulin resistance are strongly associated with more severe acne in adult women, along with a higher incidence of menstrual irregularities and PCOS characteristics.
3 citations
,
November 2022 in “Separations” This study successfully established and validated a method using LC-MS/MS to measure multiple androgens in plasma, finding that individuals with acne had higher levels of certain androgens compared to those with obesity.
In this study, researchers observed that individuals with acne vulgaris in the Qassim Region of Saudi Arabia had a significantly higher rate of vitamin B12 deficiency, suggesting a potential association that warrants further investigation.
30 citations
,
April 2007 in “Dermatologic Clinics” This review discusses the mechanisms by which isotretinoin and hormonal therapy treat acne through their effects on sebaceous glands, reporting no new clinical results.
4 citations
,
August 1999 in “Clinical Cosmetic and Investigational Dermatology” This study highlights the potential role of the CYP21A2 and CYP19A1 genes in severe acne vulgaris among Han Chinese, especially males.
1 citations
,
January 2023 This article reviews the causes and treatment options for hyperandrogenism-related hirsutism and acne in women, reporting no new results and highlighting the variability in treatment needs based on severity and personal desire.
2 citations
,
November 2018 in “Clinical and Experimental Dermatology” This correspondence discusses acne development in male androgenetic alopecia but reports no new clinical findings.
8 citations
,
September 2018 in “Journal of Cosmetic Dermatology” This study found that serum irisin levels were significantly lower in patients with acne vulgaris compared to healthy controls and were negatively correlated with insulin resistance and disease severity.
2 citations
,
July 2011 in “Journal of the Egyptian Women's Dermatologic Society (Print)” This study found that frequent consumption of nuts, chocolate, candy, and red tea was associated with more severe acne, while eating fresh vegetables was linked to milder acne in these patients.
November 1993 in “PubMed” This article reviews the role of androgens in skin metabolism and diseases like acne and androgenic alopecia, but reports no new clinical results; the authors note unresolved issues regarding androgen interactions in skin structures.
9 citations
,
January 2020 in “Zenodo (CERN European Organization for Nuclear Research)” This review discusses acne vulgaris, its causes, and impacts without presenting new findings; the authors note anxiety and depression in acne patients are not linked to oxidative stress.
3 citations
,
January 2016 in “Annals of Dermatology” This article discusses the multifactorial nature of acne, including its association with follicular hyperkeratosis, sebaceous lipids, Propionibacterium acnes, and perifollicular inflammation, but reports no new clinical findings.
24 citations
,
December 1988 in “British Journal of Dermatology” This study found no correlation between acne severity and clinical signs of androgenicity in women, suggesting factors other than hyperandrogenaemia may contribute to acne development.
1 citations
,
December 1978 in “British journal of dermatology/British journal of dermatology, Supplement” Hormonal imbalances in congenital adrenal hyperplasia cause acne.
3 citations
,
July 2011 in “Journal of the Egyptian Women's Dermatologic Society (Print)” This study observed a high prevalence of postadolescent acne in adult women, which was often inflammatory and moderately severe, with persistent acne in half the cases and frequent involvement of the mandible.
47 citations
,
September 2016 in “Reviews in endocrine and metabolic disorders” This review discusses the steroidogenic properties of human skin and suggests that impaired steroidogenesis may be linked to conditions like acne, rosacea, atopic dermatitis, and androgenic alopecia, but reports no new clinical results.
9 citations
,
March 2019 in “European Journal of Sport Science” This article discusses laboratory and physical markers that may help detect androgenic anabolic steroid abuse in athletes and reports no new primary research results.
110 citations
,
October 2013 in “The Journal of Sexual Medicine” This study found that testosterone therapy in trans men increased facial and body hair growth while the prevalence and severity of acne peaked at 6 months but were primarily mild after long-term treatment.