Acne Development in Male Androgenetic Alopecia

November 2018 in “ Clinical and Experimental Dermatology ”

A. Rajan, J. Grotts, Chee-Leok Goh

androgenetic alopecia acne vulgaris hyperandrogenism insulin resistance AGA acne

TLDR Acne is more common in men with male pattern baldness due to increased hormone levels.

Male androgenetic alopecia (AGA) and acne vulgaris may be linked through hyperandrogenism. A retrospective chart review of 339 male patients with AGA aged 18-65 years at UCLA Dermatology Clinic during the period 2013-2017 was performed. The study found a statistically significant risk of having a concurrent diagnosis of acne in patients with underlying AGA compared with healthy controls. The study suggests that AGA is part of a systemic condition of hyperandrogenism requiring comprehensive treatment and management, owing to complications such as acne, diabetes, coronary artery disease, and insulin resistance.

View this study on academic.oup.com →

Discuss this study in the Community →

Research cited in this study

5 / 5 results

research Glycolipid and Hormonal Profiles in Young Men with Early-Onset Androgenetic Alopecia: A Meta-Analysis

15 citations, August 2017 in “Scientific Reports”

Young men with early hair loss have slightly worse blood sugar and fat levels, suggesting possible health risks and need for monitoring.

research A Comparison of the Hormonal Profile of Early Androgenetic Alopecia in Men With the Phenotypic Equivalent of Polycystic Ovarian Syndrome in Women

47 citations, June 2016 in “JAMA Dermatology”

Men with early hair loss have similar hormone levels to women with PCOS, possibly increasing risk of obesity and heart issues.

Prevalence of Androgenic Alopecia in Patients with Polycystic Ovary Syndrome and Characterization of Associated Clinical and Biochemical Features

research Prevalence of Androgenic Alopecia in Patients with Polycystic Ovary Syndrome and Characterization of Associated Clinical and Biochemical Features

48 citations, February 2014 in “Fertility and Sterility”

Women with PCOS often have hair loss, which is linked to acne or excess body hair but not to worse hormone or metabolic issues.

research Association of Androgenetic Alopecia With Mortality From Diabetes Mellitus and Heart Disease

49 citations, May 2013 in “JAMA Dermatology”

Hair loss links to higher death risk from diabetes and heart disease; not a direct cause, but a marker for risk factors.

research Androgenetic Alopecia: Pathogenesis and Potential for Therapy

174 citations, November 2002 in “Expert Reviews in Molecular Medicine”

Hair loss needs more research for better treatments.

Related Community Posts Join

6 / 1000+ results

community Most Recent Interesting Hairloss Studies: 10% Minox vs 5% Minox / Radio Rrequency Treatment for AA / Topical Ketoconazole / PRP+Minox vs Minox vs PRP / Alopecia as a systemic disease

in Treatment 88 upvotes 4 years ago

Treatments for hair loss, such as topical minoxidil, platelet-rich plasma therapy with or without minoxidil, ketoconazole, non-abative radio frequency, natural products, finasteride and cortexolone 17 alpha propionate. The post evaluates the efficacy and safety of these treatments in various studies.

community Diffuse hair loss and scalp biopsies

in Research 692 upvotes 4 months ago

Scalp biopsies are crucial for diagnosing hair loss conditions like Diffuse Unpatterned Alopecia (DUPA) and retrograde hair loss, as treatments like finasteride and dutasteride may not be effective if other conditions are present. Combining PPAR-GAMMA agonists with retinoids could improve treatments for conditions like Lichen Planopilaris.

community Getting Ed from 1mg of fin not sure what to do

in Finasteride 190 upvotes 4 months ago

The user experienced erectile dysfunction from 1mg finasteride and sought advice on whether to continue, reduce dosage, or switch treatments. Suggestions included switching to topical finasteride, adding minoxidil, or trying dutasteride.

community Received Kintor’s KX-826 Today

in Product 84 upvotes 4 months ago

A user received Kintor’s KX-826/Pyrilutamide and shared initial impressions, noting concerns about the product's labeling and marketing. Other users discussed the legitimacy of the product, its effectiveness, and compared it to other treatments like Minoxidil and Finasteride.

community Androgenetic alopecia is a skin disease: DHT-mediated skin disorders

in Research/Science 65 upvotes 1 year ago

Dihydrotestosterone (DHT) impacts various skin conditions, including Androgenetic alopecia and seborrheic dermatitis, by causing overactivity in sebaceous glands. Topical medications Tacrolimus and Clobetasol can reduce these inflammatory conditions, and treatments like RU58841, Minoxidil, and Finasteride may also be beneficial.

community DHT Itch is real. The connection between Acne and Male Pattern Baldness shows this

in Research/Science 64 upvotes 1 year ago

The conversation discusses the link between seborrheic dermatitis, acne, and male pattern baldness, suggesting that DHT may cause both skin conditions and hair loss. Treatments mentioned include RU58841, finasteride, dutasteride, minoxidil, Nizoral shampoo, and other topical anti-androgens.

Similar Research

6 / 1000+ results

research Sebaceous Immunobiology: Skin Homeostasis, Innate Immunity Coordination, Inflammatory Response, and Disease Associations

21 citations, November 2022 in “Frontiers in immunology”

Sebaceous glands play a key role in skin health, immunity, and various skin diseases.

research Idiopathic Hirsutism: Androgen Role and Treatment Options

47 citations, August 2000 in “Endocrine Reviews”

The document concludes that more research is needed to understand excessive hair growth in women with normal hormone levels and regular ovulation.

research Acne-Associated Syndromes: Models for Better Understanding of Acne Pathogenesis

99 citations, December 2010 in “Journal of The European Academy of Dermatology and Venereology”

The document concludes that certain genetic mutations and dietary factors are involved in acne development, and treatments like isotretinoin and diet changes can help manage it.

research Acne as a Chronic Systemic Disease

71 citations, November 2013 in “Clinics in Dermatology”

Acne is a chronic disease linked to various systemic conditions and has significant psychological and social effects.

research Dermatologic Manifestations of Polycystic Ovary Syndrome

76 citations, January 2007 in “American Journal of Clinical Dermatology”

Women with PCOS often have skin problems like excessive hair, acne, hair loss, and dark patches, which can be treated with hormonal and non-hormonal therapies.

research The Androgen Excess and PCOS Society Criteria for the Polycystic Ovary Syndrome: The Complete Task Force Report

1540 citations, October 2008 in “Fertility and Sterility”

The report concludes that PCOS is mainly a condition of excess male hormones and its definition may change as new information is discovered.