The Relationship Between Nutritional Anemia and Acne: A Case-Control Study

    May 2023 in “ Cureus
    Norah M Alharbi, Fatimah A AlGhofaili, Jolan S Alsaud, Lina M Asiri, Shumukh M. Almutairi, Dalal M Alruqayi, Maha K Alharbi
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    Studysummary In this study, researchers observed that individuals with acne vulgaris in the Qassim Region of Saudi Arabia had a significantly higher rate of vitamin B12 deficiency, suggesting a potential association that warrants further investigation.
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    This case-control study investigated the relationship between acne and nutritional anemia among 114 individuals aged 15 to 25 in the Qassim Region of Saudi Arabia. The study found that patients with acne vulgaris had a significantly higher prevalence of vitamin B12 deficiency (38.6%) compared to the control group, with a p-value of 0.041. Although the patient group showed lower levels of mean corpuscular volume, vitamin B12, ferritin, mean corpuscular hemoglobin, and hemoglobin, and higher levels of mean corpuscular hemoglobin concentration and red cell distribution width, these differences were not statistically significant. The study concludes that there is a significant association between acne and vitamin B12 deficiency, suggesting the need for further research to confirm these findings.
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