May 2023 in “Elsevier eBooks” This article discusses scalp micropigmentation as a noninvasive method to conceal various forms of hair loss and scalp abnormalities and reports no clinical results; the authors highlight its safe and effective application.
September 2023 in “bioRxiv (Cold Spring Harbor Laboratory)” This study describes the use of a genetically engineered mouse model, mTurquoise2-Col4a1, to fluorescently label collagen IV and observe basement membrane dynamics during skin development, revealing its stability and pliability during rapid growth phases.
February 2024 in “Animals” This study observed that alopecia in rhesus macaques follows a seasonal pattern, with the highest hair loss in spring, and varies with reproductive state, as pregnant females experience the most significant alopecia and lowest hair regrowth, which resumes postpartum.
1 citations
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November 2017 in “The journal of investigative dermatology/Journal of investigative dermatology” In this study, Makarova et al. found that topical vitamin D3 significantly delayed basal cell carcinoma development in UVR-exposed, BCC-prone mice, while oral vitamin D3 supplements did not prevent carcinogenesis, suggesting a potential role of UV-induced vitamin D3 in inhibiting tumor growth.
April 2016 in “Journal of Investigative Dermatology” This study found that male pattern baldness was associated with an increased risk of squamous cell carcinoma and basal cell carcinoma, particularly at the scalp.
February 2026 in “International Journal of Pharmaceutics” 3 citations
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November 2005 in “British Journal of Dermatology” In this case study, a 21-year-old man with alopecia universalis experienced temporary hair regrowth after treatment with recombinant human bone morphogenetic protein-2 following a tibial fracture.
April 2016 in “Journal of Investigative Dermatology” This study found that trametinib and vemurafenib increased sebum production and gene expression related to lipid accumulation in hamster sebocytes, which may help explain certain side effects in patients.
July 2023 in “International Journal of Molecular Sciences” In this study, Trapa bispinosa Roxb. pericarp extract demonstrated inhibitory effects on 5α-reductase activity both in vitro using LNCaP cells and in vivo in a mouse model of benign prostatic hyperplasia, suggesting its potential role in managing the condition.
2 citations
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May 2024 in “International Journal of Molecular Sciences” This study found that in a mouse model of psoriasis, depleting CD169+ macrophages led to milder symptoms and decreased inflammation, suggesting these macrophages play a crucial role in psoriasis development.
April 2023 in “Journal of Investigative Dermatology” CD206+ macrophages are crucial for hair growth in alopecia areata treatment.
10 citations
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January 2012 in “Journal of Oncology” This paper explores the relationship between the dermal extracellular matrix and cutaneous malignant melanoma, suggesting that ECM involvement may play a key role in the cancer's growth, invasiveness, and initial metastasis.
April 2001 in “Dermatologic Surgery” This article proposes a standardized naming system for areas of the balding scalp to improve communication among hair restoration professionals, but it reports no clinical results.
May 2023 in “Journal of Ethnopharmacology” In this study, Allium macrostemon Bunge extract was found to promote hair regrowth in a testosterone-induced androgenetic alopecia mouse model by activating Wnt/β-catenin signaling and boosting hair dermal papilla cell proliferation and growth factor expression.
January 2023 in “International Journal of Trichology” This study found that bicalutamide mesotherapy resulted in subtle hair density improvements and was well tolerated by premenopausal women with androgenetic alopecia.
6 citations
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April 2013 in “Current Dermatology Reports” This review discusses the cutaneous side effects associated with vemurafenib and ipilimumab in metastatic melanoma treatment and emphasizes the importance of dermatologists in managing these skin eruptions; it reports no new clinical results.
10 citations
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March 2015 in “PubMed” This paper demonstrates that scalp micropigmentation can effectively conceal scalp and hair deformities with high patient satisfaction, offering a non-surgical alternative cosmetic solution.
August 2026 in “Clinical and Translational Science” This study evaluated two bimatoprost 1% formulations for androgenetic alopecia in men, finding both formulations achieved effective drug concentrations in the scalp with no significant differences between them, and were well tolerated over the 14-day application period.
19 citations
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May 2020 in “Cells” This study found that 5% primed conditioned medium from human umbilical cord blood-derived mesenchymal stromal cells significantly improved hair density, thickness, and growth rate in patients with androgenetic alopecia.
27 citations
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April 2019 in “Journal of The American Academy of Dermatology” This study found that melanoma on the posterior scalp is associated with worse survival compared to other body sites, while sun-exposed areas showed better survival outcomes.
April 2018 in “Journal of Investigative Dermatology” This study found that BMP signaling is involved in regulating melanogenesis, pigment transfer, and melanocyte migration, contributing to our understanding of skin pigmentation mechanisms.
5 citations
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June 2022 in “Scientific Reports” This study observed that basal cell carcinoma on the scalp shares more similar characteristics with truncal lesions than facial lesions, despite the scalp's proximity to the face.
5 citations
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July 2019 in “Photodiagnosis and photodynamic therapy” This study reports a case of a 59-year-old female with refractory follicular mucinosis and diffuse scalp alopecia who achieved complete clinical remission following treatment with a combination of topical tacalcitol and photodynamic therapy.
October 2025 in “Plastic & Reconstructive Surgery” This study evaluated the safety and effectiveness of MNC-QQ cell therapy in five men with androgenic alopecia, reporting no adverse effects and improvements in hair growth, hair density, and quality of life over six months.
In this study, melatonin implantation altered BMP2 gene expression associated with hair follicle growth in Inner Mongolia Cashmere Goats, particularly reducing expression during the follicles' resting period.
This study found that social hair plucking in captive rhesus macaques was associated with alopecia and exhibited patterns similar to both prosocial and aggressive behaviors.
15 citations
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April 2011 in “The journal of investigative dermatology/Journal of investigative dermatology” This study found that A(3)B(5) downregulates melanin production and suppresses melanoma cell growth by promoting proteasomal degradation of TRP-2.
October 2024 in “Journal of Cutaneous Immunology and Allergy” This case report describes a successful treatment of sarcoidal foreign body reactions caused by permanent makeup ink with local steroid injections, while also identifying the involvement of M2 macrophages in the reaction.
September 2026 in “Zenodo (CERN European Organization for Nuclear Research)” This research introduces the MHS Hair Restoration Protocol, which is a comprehensive approach aimed at restoring the hair follicle environment by modulating the gut-microbiome-endocannabinoidome axis and incorporating specific dietary and topical strategies, rather than focusing only on short-term hair count improvements.
18 citations
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December 2009 in “Canadian Journal of Animal Science” This study reports that BMP2 expression in goat skin is higher during late telogen and early anagen phases, indicating a potential role in hair follicle regeneration.