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This review explores the role of JAG1 in disease treatment, highlighting the need for effective methods to deliver JAG1 in its bound form to activate NOTCH signaling for therapeutic applications in craniofacial bone loss and myocardial infarction.

This review summarizes advancements in biomedical engineering for hair follicle regeneration, highlighting strategies like cell transplantation and tissue engineering to reconstruct hair follicles, and discusses both their technical limitations and potential future innovations in regenerative medicine.

This review explores how recombinant protein hydrogels, employing molecular engineering and crosslinking strategies, offer advanced applications in regenerative medicine by mimicking extracellular matrix dynamics and providing enhanced mechanical, environmental, and biological properties.

This review outlines guidelines for designing Janus hydrogel bioadhesives, highlighting their potential to enhance clinical applications in tissue repair and regenerative medicine by mimicking natural biological barriers, although challenges remain in optimizing their asymmetric surface designs.

This article reviews how biomaterials and stem cells could advance regenerative medicine but does not report new results, emphasizing the potential of combining novel biomaterials with stem cells for effective therapies.

This review reports that sodium alginate-based hydrogels show promise in biomedical applications due to their biocompatibility and versatility, but challenges such as mechanical strength and stability remain, highlighting the need for continued research to facilitate their clinical transition.

This review discusses the therapeutic properties of polydeoxyribonucleotides derived from marine organisms for wound healing and inflammation, but it reports no new clinical results.

This review discusses recent advancements in engineering bioengineered skin substitutes and highlights ongoing challenges, emphasizing the need for improvements in replicating uninjured skin; it reports no new experimental results.

This study developed a biodegradable nonwoven textile using a starch-based biopolymer and fruit extracts, resulting in materials that are stronger, more hydrophilic, and capable of releasing beneficial compounds over 72 hours, positioning them for potential use in medical, healthcare, and cosmetic applications.

This review discusses the history and development of keratin biomaterials for biomedical uses, highlighting their biological activity and biocompatibility, and provides no new research findings.

This paper critically reviews recent advances in the use of keratin-based biomaterials, highlighting their potential applications in wound healing, drug delivery, and tissue regeneration due to their biocompatibility, biodegradability, and ability to support cell growth.

This study reports that keratin-based materials derived from human hair have potential for use in tissue engineering, showing promising bioactivity and mechanical support in preliminary evaluations.

This mini-review reports that advances in microbioreactor technology, particularly with microfluidics, significantly enhance eukaryotic cell-based biomedicine by improving productivity, scalability, and reproducibility in applications like CAR T-cell manufacturing and organoid growth, though challenges in scalability and material selection remain.

Human hair keratin can be used in many medical applications.

This review discusses recent research and applications of RADA16 and RADA16-based peptide scaffolds in biomedicine, including their roles in tissue repair and drug delivery, but reports no new clinical results.

This study highlights the versatility and potential of injectable hydrogel nanocomposites in biomedical research, emphasizing their roles in controlled drug delivery, tissue regeneration, and treatment of various conditions, such as cardiac issues, joint diseases, and bone regeneration.

This study explored a keratin, sodium alginate, and carboxymethyl chitosan hydrogel modified with tannic acid and found it to have promising wound-healing qualities, including similar elasticity to human skin, antimicrobial and antioxidant properties, and effective water retention. These attributes suggest potential applications in biomedical engineering.

This review discusses the potential of bioprinting technology in cosmetology, particularly for improving skin functions like pigmentation restoration and hair follicle development, but reports no new clinical findings.

This review outlines the design and engineering of multifunctional hydrogels, emphasizing their evolving biomedical applications, notably in controlled drug delivery, tissue support, and disease management, and discusses their potential for clinical translation.

This review discusses how engineering cell surfaces with polyelectrolytes can address challenges in cell therapy and related biomedical fields and reports no new research findings.

This review outlines the current state and future prospects of using layer-by-layer self-assembly for cell encapsulation in biomedical applications, such as cell-based biosensors, transplantation, and tissue engineering, while also discussing its limitations and potential advancements.

This review summarizes the state of organoid technology, highlighting its potential to transform biomedical research and regenerative medicine by providing accurate models for disease study, drug discovery, and potentially developing functional organs for transplantation.

This review examined the role of organoid technology in modeling genetic diseases, highlighting its promise for understanding disease pathology and developing tailored treatments by integrating genetic insights with advancements in regenerative medicine and biological engineering.

This review highlights the potential of egg components, such as eggshell and egg yolk, in biomedical applications like tissue engineering and drug delivery but notes existing research gaps in this emerging field.

This review details how hydrogel composites play crucial roles in regenerative medicine, tissue engineering, and drug delivery systems, highlighting innovations in these applications and addressing challenges like bioactivity, biomechanical compatibility, and controlled drug release.

This review discusses the potential of baghdadite ceramic for biomedical applications such as coatings and scaffolds, and reports no new experimental findings, emphasizing its promising properties and need for further research.

This review discusses the antioxidant activity of natural polysaccharides, highlighting their potential applications in areas like drug delivery and tissue engineering, but reports no new experimental findings.

Innovative methods are reducing animal testing and improving biomedical research.

This review highlights the transformative potential of bioinspired polymers in biomedical engineering, focusing on their roles in enhancing tissue engineering, regenerative medicine, and other biomedical applications, with innovations including mimicking the extracellular matrix, self-healing, antibacterial properties, and cancer therapy.

In this study, researchers reviewed the progress and challenges in using hydrogels for 3D printing in biomedical applications, highlighting advancements in structural complexity, and identifying ongoing issues like resolution improvement, cell viability, and ethical concerns for clinical use.