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The Rotterdam Study updated findings on elderly health, focusing on heart disease, genetics, lifestyle effects, and disease understanding.

The research found that PCOS has common genetic factors regardless of how it is diagnosed and is linked to metabolic and reproductive issues.

The virus was not found in the semen and urine of a man who tested positive for COVID-19.

Oestrogens are key for bone growth during puberty in both boys and girls.

Hair loss increases with age; alcohol raises risk, more female partners lowers it.

Hibiscus plant extracts may have health benefits like lowering blood pressure and protecting the heart.

A genetic region near the PAX1 gene is linked to a higher risk of scoliosis in females.

The document concludes that early diagnosis and treatment of Congenital Adrenal Hyperplasia are crucial for preventing serious health issues and improving patient outcomes.

Hair shedding is an active process that could be targeted to treat hair loss.

Some common medications can harm male fertility, but many effects can be reversed.

New treatments for male hypogonadism are effective and should be personalized.

The document explains how the male reproductive system works, its role in making testosterone, and how conditions like obesity can disrupt it, leading to low testosterone and fertility issues.

Mood stabilizers like lithium and anticonvulsants have side effects that can lead to patients stopping their medication, and managing these effects is important for treatment adherence.

Researchers found 63 genes linked to male-pattern baldness, which could help in understanding its biology and developing new treatments.

Hair sensitivity to androgens is partly controlled by specific enzyme expressions in different hair areas.

Lower levels of certain brain chemicals are linked to worse PTSD symptoms in men.

Bimatoprost, a glaucoma medication, may also help treat hair loss.

Selective non-steroidal inhibitors of 5α-reductase type 1 can help treat DHT-related disorders.

The combination of cyproterone acetate and testosterone enanthate is highly effective in preventing sperm production and could be a good reversible male contraceptive.

The conclusion is that genetic changes in the glucocorticoid receptor can lead to conditions affecting stress response, immunity, and metabolism, requiring personalized treatment.

Panax ginseng is generally safe with mild side effects and may have health benefits, but more research is needed.

*Acorus calamus* has many medicinal benefits but needs more safety research.

Certain metabolites are lower in women with PCOS and could be potential markers for the condition.

New steroidal compounds could be effective for treating conditions related to 5α-reductase enzyme activity.

Male hormones, or androgens, affect women's health in areas like mood and bone density, and hormone replacement therapy using antiandrogenic progestogens can improve mood disorders and alertness in menopausal women.

Androgens may influence T cells, contributing to higher autoimmune liver disease risk in women.

Mutations in the WNT10A gene can cause skin, hair, teeth, and other disorders, and may also affect other areas like kidney and cancer, with potential for targeted treatments.

Antiandrogens are effective for conditions like prostate cancer and skin issues, but more research is needed to confirm their benefits and minimize side effects.

New treatments for hair loss show promise, especially finasteride for men and a stronger minoxidil formula.

Adults with certain skin conditions may have higher levels of inflammation in their body.