Search

everythingexperts & clinicslearnfaqsresearchcommunity

for

Search:↓

This review discusses the properties and therapeutic potentials of beta-sitosterol, highlighting a need for more detailed studies on its mechanisms and long-term effects in humans; it reports no new results.

This study reviews iron metabolism in the skin, highlighting how differentially expressed genes regulate iron recycling in the epidermis, and discusses changes in iron metabolism related to skin diseases.

This study found that oxybenzone is very stable under light exposure, contradicting previous findings of its oxidation to semiquinone after solar irradiation.

This study in humans and pigs found that finasteride metabolism is significantly influenced by CYP3A4, with induced metabolism decreasing and inhibited metabolism increasing plasma exposure of the drug.

This case report details a family in Iraq with biotin deficiency, highlighting improved outcomes in surviving children following diagnosis and lifelong biotin supplementation.

This study concluded that two different finasteride tablet formulations are bioequivalent based on their pharmacokinetic profiles in a crossover trial with male subjects.

This study engineered a bioluminescent yeast strain responsive to androgenic chemicals, demonstrating rapid and sensitive detection suitable for high-throughput screening and environmental monitoring.

This study found that a testosterone patch and gel showed bioequivalent testosterone levels in hypogonadal men, but the patch mimicked a natural circadian profile, while the gel resulted in higher dihydrotestosterone levels.

This article discusses the preparation of tritium-labeled testosterone metabolites and reports no new experimental findings.

This study found that polymers significantly improved the chemical and microbial stability of steroid hormones in liposome formulations over eight weeks, with finasteride showing the highest diffusion rate.

This study suggests that simple absolute threshold monitoring rules for compliance using the biomarker DHT perform similarly to more complex methods in the Prostate Cancer Prevention Trial.

This article reviews strategies like microemulsions to improve adapalene delivery in acne treatment but reports no new clinical results.

This case study reports a two and a half-month-old with biotinidase deficiency who showed rapid seizure improvement with biotin treatment after presenting with convulsions and neurological symptoms.

This review highlights the role of plant-derived organic selenium compounds, noting their high bioavailability and low toxicity, and provides a comprehensive overview of selenium's uptake in plants and metabolism in humans, offering a theoretical basis for future nutritional research.

This study found that Pseudomonas DL7 completely degraded 600 mg/L of Sunset Yellow FCF in 48 hours at pH 9, indicating potential for biomineralization of this dye.

In this study, the authors reported that taking 20 mg or more of biotin can interfere with thyroid function tests, potentially leading to false diagnoses of conditions like Grave's disease.

This review introduces pharmacophore technology and discusses its applications in toxicity prediction and limits, but reports no new clinical results.

This review highlights recent advances in the use of light exposure for health purposes, examining its role in pathology, therapeutic strategies, and molecular changes, as well as discussing future developments in this globally supported field.

In this study, researchers found that biotin levels increase with age but not gender, and there is a notable negative relationship between biotin levels and triglyceride levels, suggesting biotin should be checked in patients with high triglyceride levels.

This review explores skin microbiome composition and its ecological interactions, highlighting the role of host and environmental factors in shaping the microbial community, but provides no new research findings.

This article discusses the dual nature of selenium, highlighting its essential metabolic roles and potential toxicity at high doses, and reports no new experimental findings.

This study developed a niosomal delivery system loaded with tretinoin and bicalutamide, optimized for follicular targeting in acne management, showing promising accumulation in hair follicles in animal models.

This study investigated the safety and efficacy of IV iron maltoside 1000 in treating iron-deficiency anemia among children with IBD and found a significant increase in hemoglobin levels by 6 weeks, maintained for up to a year, with minimal side effects reported.

This study found that while micronutrient abnormalities are common among patients receiving home parenteral nutrition, serious consequences from these abnormalities are rare.

This study found that the sebum partition coefficient (K(sebum)) for some drugs differs from the stratum corneum partition coefficient (K(sc)), indicating its importance for targeted drug delivery into hair and sebaceous follicles.

This study found that Finasteride may spontaneously diffuse into an SDS-based model cell membrane at a significant rate, with distinct behavior in polar and non-polar solutions.

This review discusses using extracellular vesicles as less invasive surrogates for assessing drug-metabolizing enzymes and transporters, suggesting potential advancements in precision therapy, but reports no new clinical results.

This study found that microbial transformation of dihydrotestosterone with two types of fungi produced eight metabolites, among which metabolites 5–7 were significant inhibitors of butyrylcholinesterase, suggesting potential in Alzheimer's disease management.

The algae grew better and fixed nitrogen more efficiently when they worked together, using nitrogen and iron.