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    Optimization, Characterization, and Follicular Targeting Assessment of Tretinoin and Bicalutamide Loaded Niosomes

    November 2023 in “ Scientific Reports ”
    Parisa Ghasemiyeh, Fatemeh Moradishooli, Saeid Daneshamouz … Soliman Mohammadi‐Samani
    Studysummary This study developed a niosomal delivery system loaded with tretinoin and bicalutamide, optimized for follicular targeting in acne management, showing promising accumulation in hair follicles in animal models.
    Automatically generated from the study's abstract, not written by a person, and not a review of the full paper. Not medical advice or a treatment recommendation. Read the original study, and consult a qualified healthcare professional before changing treatment. Full disclaimer
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    Research cited in this study 8

    1. Development and Evaluation of Finasteride Niosomes Targeting Hair Follicles for Androgenic Alopecia Management Journal of Drug Delivery Science and Technology · 2023
    2. Optimization of Lipid-Based Nanoformulation for Cutaneous Targeting: Niosomes as Potential Candidates European journal of pharmaceutical sciences · 2023
    3. Hair Follicle-Targeting Drug Delivery Strategies for the Management of Hair Follicle-Associated Disorders Asian Journal of Pharmaceutical Sciences · 2022
    4. Potential of Nanoparticles as Permeation Enhancers and Targeted Delivery Options for Skin: Advantages and Disadvantages Drug Design Development and Therapy · 2020
    5. Superoxide Dismutase Loaded Niosomes Delivery to Hair Follicles: Permeation Through Synthetic Membrane and Guinea Pig Skin International Journal of Applied Pharmaceutics · 2019
    6. Cyproterone Acetate-Loaded Nanostructured Lipid Carriers: Effect of Particle Size on Skin Penetration and Follicular Targeting Pharmaceutical development and technology · 2019
    7. Androgens in Women: Hormone-Modulating Therapies for Androgen-Mediated Cutaneous Disorders Journal of The American Academy of Dermatology · 2018
    8. Determination of the Cuticle Thickness of Human and Porcine Hairs and Their Potential Influence on the Penetration of Nanoparticles into the Hair Follicles Journal of Biomedical Optics · 2009