223 citations
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January 2000 in “BioFactors” This study reports that bioactive peptides derived from food proteins may lower serum cholesterol and exhibit antihypertensive and immunostimulating effects, suggesting potential in preventing lifestyle-related diseases.
May 2025 in “Wound Repair and Regeneration” This study found that the peptide TSN6 increased epidermal thickness and promoted hair follicle formation in dermal–epidermal composites grafted onto nude mice, with TSN6-treated composites showing more hair follicles and retained grafts compared to control groups.
July 2024 in “Journal of Investigative Dermatology” Bioactive peptides improve graft survival and new hair growth.
This literature review on neurocosmetics found that both nature-derived peptides and synthetic molecules can improve skin concerns like aging and pigmentation, while also promoting emotional well-being; however, gaps in long-term efficacy and personalized approaches remain.
11 citations
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April 2020 in “Nutrafoods - International Journal on Nutraceuticals, Functional Foods and Novel Foods” In this study, Bioactive Collagen Peptides supplementation increased hair follicle cell proliferation and improved hair thickness in healthy women over 16 weeks compared to a placebo.
4 citations
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May 2022 in “Journal of Drug Delivery Science and Technology” This research observed that nanoliposomes delivering a combination of bioactive peptides significantly promoted hair growth in vitro and in vivo by enhancing the proliferation and function of hair growth-targeted cells in C57BL/6 mice, suggesting a promising approach for treating androgenetic alopecia.
March 2026 in “International Journal of Cosmetic Science” This research reports that KCV and its palmitoylated derivatives show strong effectiveness in strengthening hair proteins, indicating their potential for use in advanced hair care products.
May 2023 in “Antioxidants” In this study, researchers found that supramolecular peptide self-assembling materials derived from Pacific oysters exhibit promising effects for skin wound healing in vitro and in vivo, demonstrating procoagulant, antioxidant, anti-inflammatory, and regenerative properties that suggest potential as a natural treatment option.
This study found that peptides from Lablab purpureus, particularly fraction 2, demonstrated potential anticancer effects by exhibiting significant antioxidant and apoptotic activities, selectively inhibiting cancer cells with minimal impact on healthy cells.
6 citations
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April 2025 in “Food Bioscience” This study found that fish scale collagen peptide significantly promoted wound healing in mice, with the <1 kDa fractions enhancing collagen synthesis and reducing inflammation, suggesting potential clinical benefits.
10 citations
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November 2023 in “Frontiers in Pharmacology” In this study, researchers developed a self-assembling hydrogel called RADA-PDGF2 and found it to accelerate wound closure in a mouse model due to its pro-proliferative and pro-migratory properties, without causing cytotoxicity or immunogenicity.
April 2024 in “Más dermatología” This study reported that bioactive peptides from skin collagen, obtained through selective hydrolysis, improve skin collagen synthesis and remodeling, while inhibiting its breakdown by metalloproteinases, showing benefits such as enhanced skin hydration, elasticity, healing, and hair restoration, without associated adverse effects.
5 citations
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December 2023 in “Materials” This review paper highlights the development and application of organic and biogenic nanocarriers for delivering bioactives, focusing on eco-friendly and sustainable nanotechnology strategies while addressing challenges like toxicity and paving the way for future innovations in green solution approaches.
17 citations
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April 2020 in “Dermatology and Therapy” In this randomized double-blind study, 160 adults with alopecia areata showed significant improvements in hair loss severity after using a bioactive peptide cosmetic product that mimics platelet-rich plasma, while the placebo group showed no significant change, underlining the treatment's potential effectiveness.
1 citations
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April 2023 in “Scientific Reports” This study reported that newly developed RADA16-I peptide hybrids, with active motifs like GHK and KGHK, demonstrated improved wound healing in a mouse skin injury model without cytotoxicity, suggesting they might be effective scaffolds for tissue engineering and regeneration.
This review concluded that the efficacy of cosmeceutical hair serums for addressing hair loss lies in their use of bioactive peptides and plant compounds, like flavonoids and sterols, that target eight key contributing factors identified in hair loss conditions.
262 citations
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May 2017 in “Nanomedicine” This review examines recent advancements in electrospun nanofibers for wound healing applications, but reports no new experimental results, highlighting their potential in sutures, dressings, and skin regeneration.
1 citations
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November 2023 in “Polymers” This review examines how incorporating various polymers and active ingredients into polyurethane dressings can enhance their properties and adaptability for better wound repair and regeneration, suggesting a promising direction for developing advanced functional dressings.
9 citations
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November 2019 in “Scientific reports” This study isolated a bioactive peptide from Trapa japonica fruit and found that it may protect human dermal papilla cells from DHT-induced stress, suggesting potential for biomedical applications.
In this study, researchers investigated the impact of a bioactive peptide derived from amphibians on hair follicle regeneration in diabetic skin, focusing on its potential to enhance wound healing and reduce infection risk.
May 2026 in “Journal of Nanobiotechnology” This study found that using a palmitoylated peptide, Pal-MPAPO, delivered through hydrogel microneedles effectively promoted hair regrowth in mice with efficacy comparable to minoxidil, while requiring less frequent application.
January 2025 in “Pharmaceuticals” This review discusses the potential of peptide-based hydrogels as biomaterials for treating chronic wounds and reports no new clinical findings.
November 2020 in “The Royal Society of Chemistry eBooks” This book discusses the development and applications of peptide-based biomaterials for healthcare, but it reports no new research findings.
5 citations
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November 2023 in “Pharmacognosy Reviews/Bioinformatics Trends/Pharmacognosy review” This systematic review highlights the diverse uses and bioactivities of Impatiens plants, particularly their antimicrobial, cytotoxic, anti-inflammatory, anti-anaphylactic, and antioxidant properties, while noting the need for more research to validate their ethnobotanical applications and isolate major bioactive compounds.
4 citations
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September 2025 in “Pharmaceutics” This review highlights the potential of natural hydrogels as advanced wound dressings, emphasizing their capabilities in mimicking the extracellular matrix, supporting healing, and delivering therapeutic agents for chronic and infected wound care.
2 citations
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March 2020 in “Journal of Pharmacognosy and Phytochemistry” This review discusses the health benefits and therapeutic potential of Ganoderma lucidum, but it reports no new clinical results and emphasizes the need for further research and compound discovery.
35 citations
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January 2017 in “International Journal of Food Properties” This study observed that a peptide showed higher antioxidant and metal ion chelation activity compared to its encapsulated version cross-linked in calcium alginate beads.
July 2026 in “ACS Pharmacology & Translational Science” This source provides a review of patents on the use of fish collagen peptides in wound care, highlighting benefits like skin hydration, scar repair, and antiaging, while emphasizing the need for further clinical research to validate these applications.
12 citations
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April 2023 in “Frontiers in Materials” This review discusses the biofunctionalization of hydrogel scaffolds for vascular tissue regeneration and reports promising results from in vivo studies, such as improved angiogenesis and healing in pressure ulcers when using specific peptides.
April 2025 in “Cosmetics” In this study, synthesized composite nanocarriers containing ribose and peptides demonstrated enhanced transdermal delivery, improved uptake by skin cells, promoted cell proliferation, enhanced antioxidant enzyme activities, and increased autophagy, suggesting a potential for more effective skin anti-aging treatments.