Investigation of the Efficacy of Fish Scale Collagen Peptide on Wound Healing Through Various Administration Routes

This study investigates the efficacy of fish scale collagen peptide (FSCP) in promoting wound healing using a mouse model with full-thickness skin injuries. FSCP was administered through gavage and topical routes, demonstrating significant acceleration in wound healing. The study found that FSCP, particularly the fraction smaller than 1 kDa, enhanced collagen synthesis, reduced inflammation, and improved the wound healing rate to over 99% in both administration groups. Key markers of healing included shortened scab shedding time and increased granulation tissue and collagen deposition. The research highlights FSCP's potential as a non-toxic, bioactive compound for clinical wound healing treatments.