Search

everythingexperts & clinicslearnfaqsresearchcommunity

for

Search:↓

This study found that sex steroid hormone receptors are largely maintained during the transformation of skin appendages to neoplasms, except for androgen and estrogen receptors in sweat and sebaceous gland tumors.

This study found that the vitamin D receptor is crucial for initiating the postnatal hair follicular cycle in mice, preventing alopecia associated with its inactivation.

This study found that C. obtusa oils promoted hair growth in shaved mice and increased the expression of a hair growth regulator, VEGF, in a cell line.

This study found that valproic acid promoted human hair growth by increasing β-catenin levels, suggesting it may be a potential therapeutic option for alopecia.

This study observed that epidermal growth factor and fibroblast growth factor have distinct roles in sheep skin, with EGF involved in differentiation and FGF in bulb proliferation and fiber growth.

This review discusses the potential role of extracellular vesicles in modulating hair follicle dynamics and reports no new clinical results; future investigations may inform treatment strategies for skin disorders.

In this study using a mouse model and human hair follicle cells, shikimic acid was found to promote hair growth and may serve as a new therapeutic agent for alopecia.

This research discusses a novel imaging approach in live mice to study stem cell and niche interactions in tissue homeostasis and reports no new results.

This study found that human scalp hair follicles can internally operate a Cori cycle, synthesize glycogen in the presence of lactate, and modulate growth through glycogen phosphorylase activity.

This review evaluates dihydrotestosterone's role in androgenic alopecia and proposes a model suggesting that chronic scalp tension and inflammation contribute to hair follicle miniaturization, identifying fibrosis, calcification, and tension as treatment targets.

This study found that Wnt/β‐catenin signaling influences the hair follicle regeneration process by prompting quiescent stem cells to enter the cell cycle and is necessary for maintaining the stem cell pool.

This review discusses methods for evaluating hair growth-promoting effects of candidate substances for androgenetic alopecia, focusing on cell assays, organ cultures, and animal models, and reports no new results.

This study identified somatostatin as a potential secretory factor contributing to the immune privilege of human hair follicles.

This study found that morroniside enhanced hair follicle growth and transition through the Wnt/β-catenin signaling pathway in a mouse model, suggesting its potential as a treatment for hair loss.

In this mouse study, NF-κB was shown to play a role in hair follicle cycling and morphogenesis, with specific activity patterns differing by hair type and involving noncanonical signaling for zigzag hair bending.

This study found that topical cilostazol promotes hair growth, enhances hair follicle activities, and may serve as a potential treatment for alopecia.

This study indicates that the OVOL1-OVOL2 axis may play a significant role in hair follicle differentiation and growth, potentially serving as therapeutic targets for hair disorders like alopecia and in the tumorigenesis of pilomatricoma.

This study found that keratoacanthoma of the lip likely arises from outer root sheath cells, based on the presence of specific keratin markers and periodic acid-Schiff staining patterns.

This study found that thymosin beta-4 overexpression in mice increased hair growth speed and density, likely by regulating P38/ERK/AKT signaling through VEGF expression.

This study found that ATM protein plays a crucial role in protecting human hair follicle melanocytes from oxidative stress, which is linked to the greying of hair.

In this study, EGCG from green tea promoted mink hair follicle growth and cell proliferation at specific concentrations, potentially through activation of Shh and AKT signaling pathways.

This article discusses the cell therapy potential of follicular cell implantation for hair regeneration and reports no new clinical results, emphasizing the role of dermal papilla cells in forming new follicles.

This study found that in vivo bioluminescence can track Smad2/3-dependent TGF-β signaling during the wound healing process in mice, with signaling increasing after healing rather than immediately post-wounding.

This study identified four proteins that differ between Type III and non-Type III hair in Yangtze River Delta white goats, contributing to understanding the development of high-quality brush hair.

This study identified 21 novel circular RNAs in cashmere goats, with nine significantly more expressed during the anagen phase of hair follicle growth, suggesting roles in hair regeneration and cashmere yield enhancement.

In this study, researchers identified 32 differentially expressed genes involved in androgenetic alopecia, with down-regulated genes associated with Wnt and TGF-beta signaling and up-regulated genes linked to oxidative stress pathways.

This study suggests that ADAM 10 and 12 proteases may play important roles in the regulation of hair cycling through their expression patterns in hair follicle structures.

In this study, injectable platelet-rich fibrin (i-PRF) was found to enhance the proliferative, migratory, and hair-inducing abilities of dermal papilla cells more effectively than platelet-rich plasma through the TGF-β/Smad pathway.

This review explores the potential role of caveolin-1 in cicatricial alopecia, particularly frontal fibrosing alopecia, and discusses possibilities for targeted therapies without providing new research results.

This study found that specialized nipple epidermis in mice is maintained by the repression of TGFβ signaling through estrogen, which highlights the role of hormonal regulation in epidermal maintenance.