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Early diagnosis and individualized treatment improve outcomes for Congenital Adrenal Hyperplasia.

Male and female skin differ due to hormones, affecting conditions like hair loss, acne, and skin cancer, and suggesting a need for gender-specific treatments.

Keratinocytes help heal skin wounds by interacting with immune cells and producing substances that kill pathogens.

Targeting the IL-23/IL-17 pathway effectively treats several inflammatory skin diseases.

Postpartum depression is linked to changes in brain chemicals, inflammation, stress, and certain genes, and can potentially be identified by markers like specific steroids, serotonin levels, and vitamin D levels.

Eating less sugar, milk, and saturated fats and more vegetables and fish may help treat and prevent acne.

Modulating BMP activity changes the number, size, shape, and type of ectodermal organs.

Inflammation may be linked to hair loss, and targeting specific enzymes could help treat it.

Damage to skin releases dsRNA, which activates TLR3 and helps in skin and hair follicle regeneration.

Low doses of some substances can be beneficial, while high doses can be harmful or toxic.

The telogen phase of hair growth is active and important for preparing hair follicles for regeneration, not just a resting stage.

Understanding how cells die in the skin is important for treating skin diseases and preventing hair loss.

The update highlights that non-classic congenital adrenal hyperplasia is common in women with excess male hormones, requires specific hormone tests for diagnosis, and has various treatment options depending on age and symptoms.

Macrophages help regrow hair by activating stem cells using AKT/β-catenin and TNF.

Children with atopic dermatitis often have sleep problems, affecting their growth and behavior.

Men, especially older ones with health issues like prostate cancer, may have worse COVID-19 outcomes and could benefit from therapies targeting male hormones.

Wnt and Notch signaling help wound healing by promoting cell growth and regulating cell differentiation.

Hair, teeth, and mammary glands develop similarly at first but use different genes later.

Minoxidil is the only FDA-approved topical drug for treating male or female pattern hair loss, and other medications like finasteride and dutasteride can also increase hair growth.

Hair color production is closely linked to the active growth phase of hair in mice and may also influence hair growth itself.

Activating TRPV3 stops human hair growth.

Chemotherapy often causes temporary hair loss, which is distressing and needs better treatment and support.

Both genes and environmental factors like chemicals may contribute to the increase in hypospadias, but the exact causes are still unclear.

No treatment fully prevents hair loss from chemotherapy yet.

The p75 neurotrophin receptor is important for hair follicle regression by controlling cell death.

The Wnt/β-catenin pathway helps tissue regeneration but can also cause fibrosis, and drugs that inhibit this pathway may aid in healing skin and heart tissues.

5α‐reductase isozymes are crucial for prostate development and health, and targeting them can help prevent and treat prostate issues.

Certain genetic variations in the AR and ERβ genes can affect androgen levels in women.

The Wnt/β-catenin pathway is important for tissue development and has potential in regenerative medicine, but requires more research for therapeutic use.

Eating 500 fewer calories a day and making lifestyle changes can improve PCOS symptoms and reduce diabetes risk; more research is needed on its causes and treatments.