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The article concludes that hair loss is a common side effect of drugs treating skin cancer by blocking the hedgehog pathway, but treatment should continue, and more selective drugs might prevent this side effect.

Normal skin cell renewal doesn't need RAR signaling, but vitamin A-related skin thickening does.

Skin spheroids with both outer and inner layers are key for regrowing skin patterns and hair.

The skin's layers protect, sense, and regulate the body's internal balance, but can be prone to cancer.

A new protein was made to detect specific skin cell growth receptors and worked in normal skin but not in skin cancer cells.

The study found that mouse sweat glands develop before birth, mature after birth, and have specific keratin patterns.

The document concludes that identifying the specific cells where skin cancers begin is important for creating better prevention, detection, and treatment methods.

GRK2 is essential for healthy hair follicle function, and its absence can lead to hair loss and cysts.

The skin and thymus develop similarly to protect and support immunity.

Sebaceous glands can help harvest hair follicle stem cells to regenerate skin and hair.

Skin-derived stem cells can become various cell types, including germ cell-like and oocyte-like cells.

Changes in keratin affect skin health and can lead to skin disorders like blistering diseases and psoriasis.

Different types of stem cells exist within individual skin layers, and they can adapt to damage, transplantation, or tumor growth. These cells are regulated by their environment and genetic factors. Tumor growth is driven by expanding, genetically altered cells, not long-lived mutant stem cells. There's evidence of cancer stem cells in skin tumors. Other cells, bacteria, and genetic factors help maintain balance and contribute to disease progression. A method for growing mini organs from single cells has been developed.

Epigenetic changes control how adult stem cells work and can lead to diseases like cancer if they go wrong.

New treatments targeting skin stem cells show promise for skin repair, anti-aging, and cancer therapy.

ATP-dependent chromatin remodeling is crucial for skin development and stem cell function.

Stem cell niches are crucial for regulating stem cell renewal and differentiation, and understanding them can help in developing regenerative therapies.

RSPO1 mutations in certain patients lead to skin cells that don't develop properly and are more likely to become invasive, increasing the risk of skin cancer.

Human stem cells were turned into cells similar to those that help grow hair and showed potential for hair follicle formation.

The conclusion is that teeth, hair, and claws have similar stem cell niches, which are important for growth and repair, and more research is needed on their regulation and potential markers.

The study found new details about human hair growth and suggests that preventing a specific biological pathway could potentially treat hair graying.

Ovol2 is crucial for hair growth and skin healing by controlling cell movement and growth.

Intu gene is crucial for hair follicle formation by helping keratinocytes differentiate through primary cilia.

α-parvin is necessary for skin and hair growth and for the correct orientation of skin cells.

Removing centrosomes from skin cells leads to thinner skin and stops hair growth, but does not greatly affect skin cell differentiation.

Adult esophageal cells can start to become like skin cells, with a key pathway influencing this change.

Keratin 15 is not a reliable sole marker for identifying epidermal stem cells because it's found in various cell types.

Vitamin D3 affects cell differentiation in specific skin areas.

Hair analysis for drugs needs a better understanding of how drugs enter hair, considering factors like hair structure and pigmentation.

The document concludes that better targeted treatments are needed for wound healing, and single-cell technologies may improve cell-based therapies.