M-CSF-stimulated myeloid cells can turn into skin cells and help heal wounds and regrow hair.
29 citations,
April 2019 in “Acta neuropathologica communications” Stopping mitochondrial respiration can prevent brain cancer spread in skin cancer patients, and plant compound β-sitosterol could help achieve this.
10 citations,
January 2019 in “Archives of Endocrinology and Metabolism” Testosterone therapy may slightly increase sexual desire in women with HSDD but lacks broad recommendation due to safety concerns and limited approval.
October 2022 in “Frontiers in Endocrinology” New tools show that in fish, NPY increases feeding and somatostatin decreases it.
1 citations,
January 2013 Glucosylceramides are essential for healthy skin and proper wound healing.
105 citations,
October 2017 in “Stem cells” Wnt signaling is crucial for skin development and hair growth.
130 citations,
December 1998 in “The journal of investigative dermatology/Journal of investigative dermatology” Hair follicle melanocytes die during hair regression.
41 citations,
April 2012 in “The journal of investigative dermatology/Journal of investigative dermatology” Deleting MED1 in skin cells causes hair loss and skin changes.
695 citations,
October 2011 in “Cell stem cell” Low oxygen areas help maintain and protect blood stem cells by using a simple sugar breakdown process for energy and managing their activity levels.
23 citations,
August 2018 in “Biochimica and biophysica acta. Molecular and cell biology of lipids” Different sPLA2 enzymes affect immunity, skin and hair health, reproduction, and may be potential targets for therapy.
August 2022 in “Deleted Journal” Nutritional education reduces chemotherapy side effects and improves health in breast cancer patients.
30 citations,
September 2016 in “Aging Cell” Low selenium levels can extend lifespan but worsen health issues.
73 citations,
November 2000 in “Proceedings of the National Academy of Sciences of the United States of America” There are two ways to start hair growth: one needs Stat3 and the other does not, but both need PI3K activation.
May 2023 in “Frontiers in veterinary science” A young tapir with a rare skin condition improved after treatment with wound cleaning, cream, and oral medication.
April 2012 in “Journal of the American Academy of Dermatology” People with androgenetic alopecia may have a higher risk of heart problems compared to those with alopecia areata or healthy individuals.
24 citations,
July 2011 in “British Journal of Dermatology” Men with hair loss have more DNA changes in back-of-head hair follicles, possibly protecting them from thinning.
4 citations,
January 2018 in “Advances in Experimental Medicine and Biology” The document concludes that hair follicles have a complex environment and our understanding of it is growing, but there are limitations when applying animal study findings to humans.
April 2024 in “Research Square (Research Square)” A 27-year-old with APS-1 showed improvement in symptoms after treatment.
November 2017 in “Elsevier eBooks” PCOS is a genetic disorder affecting women's reproductive health, with treatments focused on symptoms like insulin resistance and fertility.
Cross-section trichometry is an accurate method to measure hair loss and growth.
February 2013 in “Journal of the American Academy of Dermatology” Certain gene variations may increase the risk of alopecia, and platelet-rich plasma treatment can improve hair density in those with hair loss; a rare case of facial Becker's nevus was linked to uneven beard growth.
195 citations,
April 2005 in “Journal of biological chemistry/The Journal of biological chemistry” The ZIP7 gene helps control zinc levels in cells by moving zinc from the Golgi apparatus to the cytoplasm.
54 citations,
December 2007 in “Best Practice & Research Clinical Endocrinology & Metabolism” Targeting glucocorticoid action might help treat type-2 diabetes, but human trials are needed.
41 citations,
June 2013 in “PLOS ONE” Engineered skin substitutes can grow hair but have limitations like missing sebaceous glands and hair not breaking through the skin naturally.
40 citations,
December 2012 in “Epilepsia” Neurosteroids change how GABA_A receptors work in the brain, which could be important for treating temporal lobe epilepsy.
32 citations,
July 2001 in “Endocrine Practice” Insulin-sensitizing drugs like metformin can help with ovulation, weight loss, and lower testosterone in some women with PCOS.
24 citations,
July 2011 in “PubMed” Thyroid hormones affect skin texture, hair and nail growth, and can cause skin diseases related to thyroid problems.
2 citations,
January 2019 in “Elsevier eBooks” Biotin supplements are unnecessary for most people but may help with certain conditions like biotin deficiency, brittle nails, and some hair loss.
June 2021 in “bioRxiv (Cold Spring Harbor Laboratory)” Gene therapy in mice increased lifespan and improved health without causing cancer.
405 citations,
May 2007 in “Journal of The American Academy of Dermatology” Obesity affects skin health, causing conditions like acanthosis nigricans and may require different treatment approaches.