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The analysis of a large pilomatricoma revealed five distinct areas with different gene activity related to hair growth and tumor development.

Retinoic acid helps change skin cells and is important for skin development and hair growth.

Deleting the CRIF1 gene in mice disrupts skin and hair formation, certain proteins affect hair growth, a new compound may improve skin and hair health, blood cell-derived stem cells can create skin-like structures, and hair follicle stem cells come from embryonic cells needing specific signals for development.

MOF controls key genes for skin development by regulating mitochondrial and ciliary functions.

The testes produce sperm and hormones essential for male development.

A specific enzyme is essential for proper hair follicle stem cell development and healthy skin.

Herbal nano-formulations show potential for effective skin delivery but need more research.

Testosterone can cause acne and male-pattern baldness, affects hair growth in men and women, and makes male skin more sensitive.

A gene mutation worsens skin irritation in mice due to a lack of certain fats.

The book provides detailed information on natural ingredients in beauty products and emphasizes the need for more human trials to confirm their effectiveness.

Melatonin may benefit skin health and could be a promising treatment in dermatology.

Liposomal systems show promise for delivering drugs through the skin but face challenges like high costs and stability issues.

PPARγ is crucial for skin health but can have both beneficial and harmful effects.

Keratinocytes help keep hair follicle cells and skin cells separate in 3D cultures, which is important for hair growth research.

Pangolins have lost some skin-related genes, but kept others, leading to their unique scales and skin features.

Vitamin B5 and coenzyme A may help regulate the immune system and could improve treatments for chronic diseases and cancer.

Dr. Jia-You Fang is a highly experienced researcher in drug delivery and related fields, with numerous publications and international collaborations.

Hair follicles evolved from oil glands, with hair aiding secretion transport.

Human prenatal skin develops an immune network early on that helps with skin formation and healing without scarring.

Lipid nanoparticles improve drug delivery through the skin, offering stability, controlled release, and better compatibility with skin.

The skin acts like an endocrine organ, producing hormones that affect various body functions and skin health, and understanding this can lead to new treatments.

The article concludes that while we understand a lot about how melanocytes age and how this can prevent cancer, there are still unanswered questions about certain pathways and genes involved.

TGM3 is important for skin and hair structure and may help diagnose cancer.

Understanding androgen receptors, oxidative stress, and inflammation is key to developing better skin disease treatments.

ARQ-234, a protein designed to treat atopic dermatitis, shows increased effectiveness in early testing.

Inhibiting EGFR weakens skin's defense against bacteria.

Artificial skin is improving wound healing and shows potential for treating different types of wounds.

Lizards can regrow their tail scales with the same structure, distribution, and gender-specific features as the original ones, and this unique ability is not seen in adult mammals.

Topical treatments can deliver active molecules to skin stem cells, potentially helping treat skin and hair disorders, including skin cancers and hair loss.

Active transdermal technologies in cosmetics help deliver skin treatments effectively, but their safety and effectiveness depend on skin type and treatment choice.