TLDR Understanding androgen receptors, oxidative stress, and inflammation is key to developing better skin disease treatments.
The document discusses the role of androgen receptors, oxidative stress, and inflammation in the development of skin diseases. It highlights that the skin, being the largest organ and a primary defense barrier, faces significant challenges in treatment development due to the complex and multifactorial nature of skin disorder pathogenesis. Understanding the interplay between these factors is crucial for advancing drug discovery and creating effective treatments for various skin conditions.
124 citations,
July 2012 in “Archives of Dermatological Research” Targeting androgen receptors could be a promising way to treat skin disorders with fewer side effects.
77 citations,
July 2020 in “Journal of the European Academy of Dermatology and Venereology” Environmental factors, hormones, nutrition, and stress all significantly affect skin health and aging.
16 citations,
July 2012 in “Current pharmaceutical biotechnology” New treatments for skin conditions related to the sebaceous gland are being developed based on current research.
2 citations,
May 2023 in “Frontiers in Pharmacology” Natural products may help treat skin inflammation from abnormal adrenal hormones.
2 citations,
August 2019 in “Journal of skin and stem cell” The study concludes that regulating apoptosis could lead to new treatments for various skin and hair conditions.
March 2024 in “Current issues in molecular biology” Personalized medicine in dermatology uses molecular biomarkers to improve diagnosis and treatment but needs further advancements for practical use.
