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European patent law now allows patents for new uses and dosages of known drugs, but protection scope is unclear.

Skin grafts on mice can cause an immune response leading to hair loss, useful for studying human hair loss conditions.

Mice without the vitamin D receptor gene lose hair due to disrupted hair follicle cycles.

Scientists found a gene in mice that causes early hearing loss.

Cationic polymers improved liposome stability and increased skin absorption of aciclovir and minoxidil.

Both mouse and rat models are effective for testing alopecia areata treatments.

The document concludes that the skin's immune system is complex, involving interactions with hair follicles, nerves, and microbes, and can protect or cause disease, offering targets for new treatments.

Cyclosporin A helps mice grow hair by blocking a specific protein activity in skin cells.

Current and future treatments for alopecia areata focus on immunosuppression, immunomodulation, and protecting hair follicles.

Hair loss in mice starts with immune cells damaging hair roots before it becomes visible.

Stump-tailed macaque best for researching hair loss causes and treatments.

The flap assay grows the most natural hair but takes the longest, the chamber assay is hard work but gives dense, normal hair, and the patch assay is quick but creates poorly oriented hair with some issues.

The document concludes that ongoing research using animal models is crucial for better understanding and treating Alopecia Areata.

The hepatitis B vaccine did not cause hair loss in the tested mice.

Alopecia Areata is an autoimmune disease affecting hair follicles, influenced by genetic and environmental factors, with rodent models being essential for research.

The meeting focused on understanding, diagnosing, and finding treatments for irreversible hair loss diseases.

Mechlorethamine treatment regrew hair in mice by killing immune cells causing hair loss without harming hair follicles.

Old treatments for other skin conditions showed promise for hair regrowth in mice with a hair loss condition.

Some mutant mice have hair with abnormal cross-linking, mainly in the cuticle, not affecting other hair parts.

Interferon gamma alone can't cause alopecia areata in C3H/HeJ mice.

Topical diphencyprone helped regrow hair in mice and rats with a condition similar to human hair loss.

Researchers found specific genes in the part of hair follicles that could help treat hair disorders.

Hair transplant complications were likely due to deep graft placement and rough handling.

Mohs micrographic surgery is effective for treating basal cell carcinoma on the eyelid, while radiotherapy has higher recurrence rates, and topical vitamin D3 may reduce and delay BCC formation in mice.

D-OCT shows increased blood vessel growth in response to tissue damage in Frontal Fibrosing Alopecia and is useful for diagnosis and monitoring.

Tofacitinib may help regrow hair in alopecia areata patients.

Blocking JAK-STAT5 signaling in mice leads to hair growth.

Triptolide effectively and safely reduces actinic keratosis lesions in mice.

Sirolimus and propranolol may reduce abnormal cell growth and improve lymphatic malformations in children.

Cow milk sugars increase fat production and inflammation in skin oil cells.