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Metformin helps with menstrual cycles and insulin levels in PCOS but is less effective for hair growth, diabetes prevention, and weight loss, and may improve fertility and reduce diabetes risk.

Only 40 nm nanoparticles can enter skin cells effectively for potential vaccine delivery.

TGF-β2 helps activate hair follicle stem cells by counteracting BMP signals.

Changing how mesenchymal stromal cells are grown can improve their healing abilities.

Fat tissue-derived cells show promise for repairing body tissues, but more research and regulation are needed for safe use.

Keratin from human hair helps nerves heal faster.

Polysaccharides have many health benefits and are used in drugs, but isolating and purifying them is complex and requires careful methods.

Hair follicles help attract immune cells to the skin during stress.

Adding chemotherapy to tamoxifen improves survival for older breast cancer patients with positive nodes.

Removing part of the vitamin D receptor stops vitamin D from working properly.

Polymeric nanoparticles show promise for treating skin diseases.

Spironolactone treatment increases the amount of testosterone available in the body.

Stem cell offspring help control their parent stem cells, affecting tissue health, healing, and cancer.

Using platelet plasma growth factors in baldness surgery can increase the number of hair follicles.

Ectodin integrates BMP, SHH, and FGF signals in developing ectodermal organs.

Patients need long-term care after bariatric surgery to manage potential nutritional and metabolic issues.

Men with baldness due to androgenetic alopecia still have hair stem cells, but lack specific cells needed for hair growth.

Drugs that block DHT production can effectively treat enlarged prostate and improve urinary issues with some sexual side effects.

BAY 43-9006 helps control kidney cancer growth but doesn't significantly increase overall survival.

The method can effectively extract biomedical information without needing expert annotation, performing better than previous models.

Diet changes can protect against harmful environmental effects on fetal development.

Cells from balding scalps have more androgen receptors than cells from non-balding scalps.

The document concludes that understanding hair follicle biology can lead to better hair loss treatments.

Food-derived peptides may help prevent diseases like high blood pressure and high cholesterol, and can support the immune system.

Mitochondrial Complex I reduces inflammation and increases bone breakdown by affecting certain immune cells.

Hair loss affects women's mental health more than men's, causing anxiety, low self-esteem, and social insecurity.

BMAL1 controls skin cell growth and UV damage risk, peaking at night.

Biomaterials with MSC-derived substances could improve tissue repair and have advantages over direct cell therapy.

Guidelines suggest various treatments for alopecia areata, but leaving it untreated is also an option as 80% cases may recover on their own.

The document concludes that the 5 alpha-reductase enzymes are important in steroid metabolism and related to various human diseases, with inhibitors used to treat conditions like male pattern baldness and prostate issues.