research A WWP2–PTEN–KLF5 Signaling Axis Regulates Odontoblast Differentiation and Dentinogenesis in Mice
WWP2 is crucial for tooth development in mice.
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research The Vitamin B5/Coenzyme A Axis: A Target for Immunomodulation?
Vitamin B5 and coenzyme A may help regulate the immune system and could improve treatments for chronic diseases and cancer.
research Prolactin: An Emerging Force Along the Cutaneous–Endocrine Axis
Prolactin may play a significant role in skin and hair health and could be a target for treating skin and hair disorders.
research Reversal of the Hair Loss Phenotype by Modulating the Estradiol-ANGPT2 Axis in the Mouse Model of Female Pattern Hair Loss
Adjusting estradiol-ANGPT2 levels can promote hair growth in female pattern hair loss.
research MiR-199a-3p Regulates the PTPRF/β-Catenin Axis in Hair Follicle Development: Insights into the Pathogenic Mechanism of Alopecia Areata
miR-199a-3p controls hair growth and is linked to alopecia areata.
research Visualizing the Novosel Formula: Comments on Dahl and Berg’s Formula for the Mean Electrical Axis of the Heart
The authors suggest standardizing how the heart's electrical axis is calculated to improve precision and consistency in ECG analysis.
research Skin Adipocyte Stem Cell Self-Renewal Is Regulated by a PDGFA/AKT Signaling Axis
PDGFA/AKT signaling is important for the growth and maintenance of certain skin fat cells.
research Control of Hair Follicle Cell Fate by Underlying Mesenchyme Through a CSL–Wnt5a–FoxN1 Regulatory Axis
Notch/CSL signaling controls hair follicle differentiation through Wnt5a and FoxN1.
research C-MYC-Induced Sebaceous Gland Differentiation Is Controlled by an Androgen Receptor/p53 Axis
The balance between androgen receptor and p53 is crucial for sebaceous gland differentiation.
research Single-Cell Transcriptomics Reveals a Senescence-Associated IL-6/CCR6 Axis Driving Radiodermatitis
Blocking certain immune signals can reduce skin damage from radiation therapy.
research Melatonin Regulates the Mitogen-Activated Protein Kinase Pathway via the CircMPP5-miR-211-MAPK3 Axis to Induce Secondary Hair Follicle Differentiation and Development in Newborn Cashmere Goat Kids
Melatonin helps improve Cashmere goat hair quality by promoting hair follicle growth through a specific cell signaling pathway.
research Hair Shaft Miniaturization Causes Stem Cell Depletion Through Mechanosensory Signals Mediated by a Piezo1-Calcium-TNF-α Axis
Hair thinning causes stem cell loss through a process involving Piezo1, calcium, and TNF-α.
research CircRNA-1926 Promotes Differentiation of Goat SHF Stem Cells into Hair Follicle Lineage by miR-148a/b-3p/CDK19 Axis
circRNA-1926 helps goat stem cells turn into hair follicles by affecting miR-148a/b-3p and CDK19.
research LncRNA-PCAT1 Maintains Characteristics of Dermal Papilla Cells and Promotes Hair Follicle Regeneration by Regulating miR-329/Wnt10b Axis
PCAT1 helps hair growth by controlling miR-329/Wnt10b.
research New Effects of Caffeine on Corticotropin-Releasing Hormone (CRH)-Induced Stress Along the Intrafollicular Classical Hypothalamic-Pituitary-Adrenal (HPA) Axis (CRH-R1/2, IP3-R, ACTH, MC-R2) and the Neurogenic Non-HPA Axis (Substance P, p75NTR and TrkA) in Ex Vivo Human Male Androgenetic Scalp Hair Follicles
Caffeine may help reduce stress-induced hair loss.
research LncRNA-599547 Contributes to the Inductive Property of Dermal Papilla Cells in Cashmere Goats Through miR-15b-5p/Wnt10b Axis
A specific RNA in cashmere goats helps improve hair growth by interacting with certain molecules.
research N6-Methyladenosine Modification of circRNA-ZNF638 Contributes to the Induced Activation of SHF Stem Cells Through miR-361-5p/Wnt5a Axis in Cashmere Goats
A specific RNA modification in cashmere goats helps activate hair growth-related stem cells.
research LSD1 Interacting With HSP90 Promotes Skin Wound Healing by Inducing Metabolic Reprogramming of Hair Follicle Stem Cells Through the c-MYC/LDHA Axis
LSD1 and HSP90 help heal skin wounds by changing hair follicle stem cells' metabolism.
research CircAGK Regulates High Dihydrotestosterone-Induced Apoptosis in DPCs Through the miR-3180-5p/BAX Axis
CircAGK affects cell death in hair cells by controlling the miR-3180-5p/BAX pathway, which can lead to hair loss.
research Botulinum Toxin Type A Alleviates Androgenetic Alopecia by Inhibiting Apoptosis of Dermal Papilla Cells via Targeting Circ_0135062/Mir-506-3p/Bax Axis
Botox can help prevent hair loss by blocking cell death in scalp cells.
research CircERCC6 Positively Regulates the Induced Activation of SHF Stem Cells in Cashmere Goats via the miR-412-3p/BNC2 Axis in an m6A-Dependent Manner
Circular RNA ERCC6 helps activate stem cells important for cashmere goat hair growth by interacting with specific molecules in an m6A modification-dependent way.
research Botulinum Toxin Type A Alleviates Androgenetic Alopecia by Inhibiting Apoptosis of Dermal Papilla Cells via Targeting Circ_0135062/MiR-506-3p/Bax Axis
Botulinum toxin type A helps treat hair loss by stopping cell death in hair follicles through a process involving certain non-coding RNAs and a protein called Bax.
research Comprehensive Transcriptome Analysis of Hair Follicle Morphogenesis Reveals That lncRNA-H19 Promotes Dermal Papilla Cell Proliferation Through the Chi-miR-214-3p/Beta-Catenin Axis in Cashmere Goats
The research found that the molecule lncRNA-H19 helps hair follicle cells grow by affecting certain cell pathways in cashmere goats.
research In Vitro Co-Culture Models of Merkel Cell-Neurite Complex in Touch Domes
The study concluded that the developed models are effective for studying hair growth mechanisms and testing new treatments.
research Neuroimmunoendocrine Circuitry of the Brain-Skin Connection
Stress can worsen skin conditions and stop hair growth by affecting the body's stress response system.
research Neuroendocrinology of the Hair Follicle: Principles and Clinical Perspectives
Hair follicles are hormone-sensitive and involved in growth and other functions, with potential for new treatments, but more research is needed.
research Steroid Biomarkers and Genetic Studies Reveal Inactivating Mutations in Hexose-6-Phosphate Dehydrogenase in Patients with Cortisone Reductase Deficiency
Certain mutations in the H6PD gene cause Cortisone Reductase Deficiency by affecting hormone production.
research Female Gonadal Function Before and After Treatment of Acromegaly
Treatment of acromegaly can improve women's reproductive health issues caused by hormonal imbalances or tumors.
research Neuroendocrine Perspectives in Alopecia Areata: Does Stress Play a Role?
Stress might contribute to hair loss in alopecia areata.
research Pathways to Inflammation: Acne Pathophysiology
Acne is caused by genetics, diet, hormones, and bacteria, with treatments not yet curative.