The Local Hypothalamic–Pituitary–Adrenal Axis in Cultured Human Dermal Papilla Cells
January 2020
in “
Research Square (Research Square)
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corticotropin releasing factor CRF human dermal papilla cells DPCs hair follicles hair growth hair loss catagen transition cell cycle arrest G2/M phase reactive oxygen species ROS anagen phase cytokine levels proopiomelanocortin POMC adrenocorticotropic hormone ACTH cortisol hypothalamic–pituitary–adrenal axis HPA axis stress hormone hair shedding hair growth phase
Preprint — not peer reviewed. This was posted to a preprint server or data repository. It has not been through a journal's review process, and its findings may change or not hold up.
Studysummary This study showed that the stress hormone CRF inhibits hair growth and induces hair loss by affecting both the proliferation of human dermal papilla cells and hair follicle function.
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