August 2020 in “Rossiiskii Zhurnal Kozhnykh i Venericheskikh Boleznei” The literature review analyzed the effectiveness of platelet-rich plasma (PRP) therapy in treating androgenetic alopecia, a condition characterized by gradual hair thinning and loss. The review compared single- and double-spin preparation methods of PRP. It concluded that PRP therapy showed promise as a treatment option due to its high tolerance and efficacy, offering a potential alternative to existing methods that have notable side effects and drawbacks.
November 2022 in “Frontiers in Medicine” This systematic review assessed the efficacy of platelet-rich plasma (PRP) in treating alopecia areata (AA) and primary cicatricial alopecias (PCAs) by analyzing 32 studies with 621 AA patients and 19 PCA patients. PRP showed promising results in AA, especially in mild cases, with better efficacy than placebo and similar efficacy to intralesional triamcinolone acetonide (TA). PRP also had benefits as an adjunctive treatment. However, its efficacy in PCAs was less clear due to limited studies and variable responses. The review emphasizes the need for more high-quality, randomized controlled trials to confirm PRP's therapeutic potential in these conditions.
7 citations,
May 2021 in “Frontiers in Pharmacology” The systematic review and meta-analysis evaluated the efficacy of platelet-rich plasma (PRP) in treating female androgenic alopecia (FPHL) and included 42 studies with 1,569 cases, of which 776 were female participants. PRP showed positive responses and improvements in hair density compared to baseline and placebo, with minimal adverse effects such as mild pain and bruising at injection sites. The study concluded that PRP is a promising treatment for FPHL, though further high-quality randomized controlled trials are needed to confirm its efficacy due to considerable heterogeneity and publication bias.
5 citations,
January 2020 in “International Journal of Trichology” The study compared microneedling (MN) alone versus microneedling with platelet-rich plasma (PRP) in treating male pattern alopecia in 30 male patients using a split-head design. Both treatments significantly increased hair thickness and density, with MN alone showing a greater increase in thickness and MN + PRP showing a greater increase in density. However, the differences were not statistically significant. Both treatments were effective, safe, and well-tolerated, but PRP did not provide additional benefits over MN alone. The study was limited by its small sample size and lack of long-term follow-up.
January 2021 in “Türk plastik cerrahi dergisi” The study evaluated the efficacy and safety of activated platelet-rich plasma (aPRP) in treating androgenetic alopecia (AGA) in 40 male patients, with 35 completing the study. Patients received 5 sessions of aPRP injections, spaced 15 days apart, with aPRP injected into one half of the scalp and placebo in the other half. Results at 1 and 3 months follow-up showed a significant increase in hair count, hair density, and anagen/telogen ratio in the aPRP-treated areas compared to placebo. The study concluded that aPRP is a safe and effective treatment for AGA, with a stabilizing effect on hair fall and potential to prevent progression of alopecia in its early stages. No major side effects were reported, but further studies with larger cohorts and longer follow-up periods were recommended.
March 2023 in “Anais Brasileiros De Dermatologia” The document reviews various treatments for female pattern hair loss (FPHL), highlighting the efficacy and safety of different therapeutic options. Topical minoxidil is the most supported treatment but is ineffective for about 40% of patients. Oral minoxidil shows promise but has potential side effects. Antiandrogens like spironolactone and bicalutamide are effective in certain cases, with cyproterone being more effective in hyperandrogenism. Emerging treatments like microneedling, platelet-rich plasma (PRP) therapy, and low-level laser therapy (LLLT) show potential but require more research. The review emphasizes the need for personalized treatment plans and further randomized clinical trials to improve FPHL management.
November 2023 in “Materials Today Bio” Light therapy might help treat hereditary hair loss by improving hair follicle growth in lab cultures.
1 citations,
May 2018 in “Plastic and reconstructive surgery. Global open” The congress discussed fat grafting, stem cells, and safety in plastic and regenerative surgery, with plans for a future meeting in Chicago.
November 2023 in “Biomaterials” Nanotechnology could improve hair regrowth but faces challenges like complexity and safety concerns.
October 2021 in “Cosmoderma” Hair loss can be managed with treatments like minoxidil, finasteride, and others, but there are still gaps in effectiveness and off-label usage is increasing.
70 citations,
February 2017 in “Dermatologic Surgery” Treatment with plasma rich in growth factors improved hair density and thickness for hair loss patients.
12 citations,
October 2017 in “Journal of Cosmetic Dermatology” Combining plasma rich in growth factors with hair transplant surgery may lead to faster recovery and better outcomes for hair loss treatment.
25 citations,
May 2014 in “Facial Plastic Surgery” PRFM may help treat hair loss, especially in mild cases.
May 2014 in “Transfusion and Apheresis Science” The study found that the quality of cord blood units remains consistent before freezing and after thawing, indicating that attached tube segments reliably represent the graft's properties.
51 citations,
March 2019 in “Journal of cellular physiology” Platelet lysate is a promising, cost-effective option for regenerative medicine with potential clinical applications.
29 citations,
December 2019 in “Stem Cells Translational Medicine” Fully regenerating human hair follicles not yet achieved.
6 citations,
September 2018 in “Journal of Stomatology, Oral and Maxillofacial Surgery” Nanofat grafting is better for delicate areas and combining it with lipofilling might improve hair loss treatment.
5 citations,
February 2019 in “Oral and Maxillofacial Surgery” Hair loss can be reversed or even cured using advanced hair restoration techniques, with rare complications like swelling and bleeding.
March 2024 in “Journal of Experimental & Biomedical Sciences/Biomedical Science Letters” BCC can protect heart cells from damage caused by oxidative stress.
145 citations,
November 2017 in “Journal of The European Academy of Dermatology and Venereology” Use minoxidil for hair loss treatment; assess results after 6 months.
132 citations,
January 2017 in “International Journal of Molecular Sciences” Fat-derived stem cells show promise for skin repair and reducing aging signs but need more research for consistent results.
76 citations,
February 2021 in “International Journal of Molecular Sciences” Mesenchymal stem cells show potential for skin healing and anti-aging, but more research is needed for safe use, especially regarding stem cells from induced pluripotent sources.
65 citations,
July 2020 in “Science Advances” Dermal exosomes with miR-218-5p boost hair growth by controlling β-catenin signaling.
50 citations,
November 2010 in “Plastic and Reconstructive Surgery” Botox increased hair count in men with baldness and might work by improving scalp blood flow.
27 citations,
September 2018 in “Nanomedicine: Nanotechnology, Biology and Medicine” Further research is needed to improve hair regeneration using stem cells and nanomaterials.
25 citations,
May 2020 in “Aesthetic Surgery Journal” The regenerative solution, tSVF, is a safe and effective treatment for various conditions like aged skin, scars, wounds, and more, but more research is needed to find the best way to use it.
15 citations,
July 2020 in “Stem Cell Research & Therapy” Stem cell therapy helps heal burn wounds, especially second-degree burns, by promoting blood vessel growth and reducing inflammation.
14 citations,
November 2020 in “International Journal of Molecular Sciences” Advanced therapies like gene, cell, and tissue engineering show promise for hair regrowth in alopecia, but their safety and effectiveness need more verification.
13 citations,
January 2016 in “Journal of cosmetology & trichology” Alternative treatments show promise for hair growth beyond traditional methods.
11 citations,
November 2018 in “Facial Plastic Surgery Clinics of North America” Adipose-derived stem cells show potential for skin rejuvenation and wound healing but require more research to overcome challenges and ensure safety.