25 citations,
October 2018 in “PloS one” Key genes regulate hair follicle phase changes in Inner Mongolia cashmere goats.
14 citations,
June 2016 in “Hypertension research” New method uses hair follicle cells to estimate human body clock phase, potentially improving sleep disorder diagnosis.
13 citations,
September 2018 in “Scientific Reports” The research found that a complex gene network, controlled by microRNAs, is important for hair growth in cashmere goats.
6 citations,
April 2022 in “Frontiers in cell and developmental biology” The research identified key proteins and genes that may influence wool bending in goats.
1 citations,
April 2019 in “Journal of Investigative Dermatology” Patients with autoimmune blistering diseases experience a reduced quality of life, with the need for better measurement tools, especially for those with mucous membrane pemphigoid.
September 2023 in “International journal of medicine” AI is revolutionizing healthcare by improving diagnosis, treatment, and monitoring, but still needs close supervision.
April 2019 in “Journal of Investigative Dermatology” The research found that certain characteristics like age, sex, race, marital status, and education level can influence whether alopecia patients stick to their hair loss treatment with topical minoxidil.
September 2004 in “Experimental dermatology” Melatonin directly affects mouse hair follicles and may influence hair growth.
437 citations,
August 2014 in “Cell metabolism” Turning white fat into brown-like fat could help fight obesity and type 2 diabetes.
207 citations,
March 2012 in “Development” Skin needs dermal β-catenin activity for hair growth and skin cell multiplication.
144 citations,
August 2019 in “Cells” The WNT signaling pathway is important in many diseases and targeting it could offer new treatments.
129 citations,
May 2015 in “Cell Stem Cell” Different types of stem cells exist within individual skin layers, and they can adapt to damage, transplantation, or tumor growth. These cells are regulated by their environment and genetic factors. Tumor growth is driven by expanding, genetically altered cells, not long-lived mutant stem cells. There's evidence of cancer stem cells in skin tumors. Other cells, bacteria, and genetic factors help maintain balance and contribute to disease progression. A method for growing mini organs from single cells has been developed.
124 citations,
February 2018 in “Nature Reviews Genetics” Stem cell plasticity is crucial for wound healing but can also contribute to cancer development.
98 citations,
July 2014 in “Trends in Molecular Medicine” Hair follicles are hormone-sensitive and involved in growth and other functions, with potential for new treatments, but more research is needed.
87 citations,
January 2016 in “Development” Blocking β-catenin in skin cells improves hair growth during wound healing.
85 citations,
October 2015 in “Proceedings of the National Academy of Sciences of the United States of America” NF-κB is crucial for zebrafish heart repair, affecting heart cell growth and repair processes.
67 citations,
January 2022 in “Theranostics” Advanced nanocarrier and microneedle drug delivery methods are more effective, safer, and less invasive for treating skin diseases.
64 citations,
November 2012 in “EMBO reports” Lamins are vital for cell survival, organ development, and preventing premature aging.
51 citations,
September 2020 in “Cell Metabolism” Glutamine metabolism affects hair stem cell maintenance and their ability to change back to stem cells.
33 citations,
June 2017 in “Developmental Biology” Mice can correct hair follicle orientation without certain genes, but proper overall alignment needs those genes.
32 citations,
July 2017 in “Wiley Interdisciplinary Reviews-Developmental Biology” Transit-amplifying cells are crucial for tissue repair and can contribute to cancer when they malfunction.
31 citations,
March 2015 in “The Journal of Steroid Biochemistry and Molecular Biology” Neuroactive steroids could become safe, effective treatments with more understanding of their complex brain actions and metabolism.
29 citations,
January 2014 in “Frontiers in physiology” Understanding and tracking our body's natural daily rhythms could help improve heart health.
19 citations,
July 2018 in “Mechanisms of Ageing and Development” Eating less can slow aging and help keep stem cells healthy by cleaning out damaged cell parts.
16 citations,
December 2018 in “Plant Science” Elevated CO2 can lessen the negative impact of water shortage on soybean roots and affects specific genes.
11 citations,
March 2019 in “EMBO molecular medicine” A defective protein in progeria causes cell death and atherosclerosis, but a treatment targeting cell stress may reduce these effects.
10 citations,
June 2019 in “International Journal of Cosmetic Science” Some plant-based chemicals may help with hair growth, but more research is needed to confirm their effectiveness.
9 citations,
October 2008 in “Mutation research” N-acetyl-L-cysteine (NAC) can prevent DNA damage and protect cells from harm.
9 citations,
July 2002 in “Journal of the European Academy of Dermatology and Venereology” The document concludes that fexofenadine reduces inflammation in chronic hives, cholestyramine helps half of pregnant women with itchy rashes, and relaxing incisions are a good alternative in facial surgery for the elderly.
4 citations,
January 2022 in “Current pharmaceutical design” Microsponges delivery system is a safe, versatile method for controlled drug release in various treatments.