40 citations
,
November 2009 in “Experimental Dermatology” This review discusses the role of the mineralocorticoid receptor in skin biology, highlighting its potential involvement in keratinocyte and hair physiology, and proposes it may affect the side effects of glucocorticoid use.
40 citations
,
January 2009 in “Skin Pharmacology and Physiology” This review discusses the potential use of cultured primary fetal cells from a single organ donation to produce therapeutic products, emphasizing the need for process consistency and safety verification, but reports no clinical results.
40 citations
,
May 1999 in “Journal of The European Academy of Dermatology and Venereology” This article outlines management guidelines for androgenetic alopecia, highlighting that continued treatment with medications like finasteride or minoxidil typically halts progression and improves hair condition in most mild to moderate cases.
39 citations
,
November 2015 in “Nanomedicine” This study found that the developed Finasteride-loaded SMEDDS improved the relative bioavailability of the drug compared to a commercial tablet, offering a promising oral delivery system for glucosteroid analogs.
39 citations
,
October 2015 in “Case Reports” In this case series, four adults developed severe, disabling multisymptom illness potentially linked to fluoroquinolone use, which persisted and progressed even after discontinuation of the drug.
39 citations
,
December 2013 in “Phytotherapy Research” This study found that hydroxysafflor yellow A-rich Carthamus tinctorius extract promoted hair growth and gene expression linked to hair proliferation in both cell cultures and mouse models.
39 citations
,
May 2011 in “European Journal of Clinical Investigation” This review discusses the various causes of hirsutism other than PCOS, emphasizing the importance of distinguishing potentially life-threatening conditions like androgen-secreting tumors from more benign causes; it reports no new clinical findings.
39 citations
,
March 2008 in “Growth hormone & IGF research” Raspberry ketone may help grow hair and improve skin elasticity.
38 citations
,
January 2023 in “International Journal of Medical Sciences” This review discusses the potential of repeated low-level red-light therapy to inhibit myopia progression through metabolic effects, highlighting its molecular and cellular impact, but reports no new clinical results.
38 citations
,
January 2016 in “Cell Death and Disease” This review discusses the role of the TCL1 transgenic mouse model in understanding chronic lymphocytic leukemia biology and highlights the importance of exploring new pathogenetic and therapeutic targets.
38 citations
,
January 2014 in “International Journal of Endocrinology” This review highlights that children with adrenal disorders may experience neurological and psychiatric symptoms, with potential long-term cognitive and behavioral effects from excess glucocorticoids.
38 citations
,
January 2011 in “Endocrine Journal” This study found that serum vaspin levels were elevated in women with polycystic ovary syndrome compared to controls, but treatment with metformin or weight loss did not significantly change these levels.
38 citations
,
August 2005 in “Veterinary dermatology” This study demonstrates that exfoliative cutaneous lupus erythematosus in German short-haired pointers involves a cellular and humoral immune response against the epidermal basement membrane, with poor response to immunosuppressive therapy.
38 citations
,
October 1988 in “Clinics in Dermatology” This article reviews the historical development of understanding the hair growth cycle, particularly anagen, catagen, and telogen phases, and reports no new clinical findings.
37 citations
,
December 2024 in “Theranostics” In this study, a newly developed nanoparticle-loaded hydrogel wound dressing demonstrated significant antibacterial, antioxidant, anti-inflammatory, and proangiogenic activities, effectively reducing pain and promoting healing in a murine burn wound model while preventing infection by *Staphylococcus aureus*.
37 citations
,
January 2023 in “Ophthalmology and Therapy” In this study, more than 25% of children experienced axial length shortening greater than 0.05 mm/year following repeated low-level red-light therapy.
37 citations
,
January 2019 in “JAMA Dermatology” This study found a bidirectional relationship between major depressive disorder and alopecia areata, with each condition significantly increasing the risk of subsequently developing the other.
37 citations
,
June 2018 in “Clinical and Experimental Medicine” This study found that patients with alopecia areata had significant systemic inflammation and vitamin D deficiency, with both conditions more pronounced as disease severity increased.
37 citations
,
May 2016 in “Deutsches Arzteblatt International” This review outlines various causes and manifestations of hair loss, highlighting that each type has distinct underlying mechanisms and requires specific treatment approaches, without reporting new clinical results.
37 citations
,
December 2014 in “Journal of Biomedical Informatics” This study introduced LabeledIn, a semi-automatic, human-reviewed catalog of drug-disease treatment relationships, highlighting the important role of human input in creating accurate and detailed drug indication resources.
37 citations
,
March 2010 in “British Journal of Dermatology” Oestrogen and thyrotropin-releasing hormone affect prolactin and its receptor in human skin and hair, suggesting new treatment options for related conditions.
37 citations
,
February 2009 in “Bioorganic & Medicinal Chemistry” This study suggests that true binary and ternary inclusion complexes were formed between finasteride and 2-hydroxypropyl-ß-cyclodextrin, with or without the addition of specific polymers.
37 citations
,
June 2002 in “The Laryngoscope” This study describes the otolaryngologic manifestations and multidisciplinary management strategies for 12 patients with ectodermal dysplasia, emphasizing the importance of early recognition for effective treatment.
36 citations
,
June 2019 in “eLife” This study introduces MicrobeFDT, a tool that clusters chemically similar compounds and links them to gut microbial enzymes and toxicities, demonstrating its utility by uncovering previously unknown metabolism of the cancer drug altretamine.
36 citations
,
August 2018 in “Dermatologic Clinics” This article reviews various hair abnormalities observable through trichoscopy in conditions like monilethrix, trichorrhexis nodosa, and ectodermal dysplasias, with no new clinical findings reported.
36 citations
,
April 2014 in “Experimental Dermatology” This article discusses the need for a personalized and stratified therapeutic approach for vitiligo, utilizing current knowledge and expertise, but it does not report new clinical results.
36 citations
,
January 2007 in “Archives of Histology and Cytology” This study suggests that the absence of alpha5(IV)/alpha6(IV) chains in certain subepidermal basement membrane spots may relate to interactions with melanocytes in human skin.
36 citations
,
January 2006 in “Veterinary Dermatology” In this study, cyclosporin effectively controlled cases of granulomatous folliculitis, furunculosis, sebaceous adenitis in cats, and alopecia areata in a dog, positioning it as a promising alternative to glucocorticoids in veterinary dermatology.
36 citations
,
October 1996 in “Dermatologic Clinics” In this study, a methanol extract of Eclipta alba was found to have dose-dependent hair growth-promoting activity in C57BL6 mice.
35 citations
,
May 2022 in “Baillière's best practice and research in clinical endocrinology and metabolism/Baillière's best practice & research. Clinical endocrinology & metabolism” This review discusses the current understanding of androgen biosynthesis, mechanisms of action, and their roles in human biology, as well as related congenital and acquired disorders, but it reports no new research findings.