This review highlights the therapeutic potential of Hibiscus rosa-sinensis, detailing its significant medicinal value for treating various conditions such as wounds, infections, and diabetes, attributed primarily to its bioactive compounds like flavonoids and tannins.
December 2024 in “Tropical Journal of Natural Product Research” This study observed that CTUMP's Herb shampoo significantly improved hair growth and density in mice compared to a saline solution, though it was less effective than minoxidil in promoting follicle development.
This study investigated the phytochemicals in Phyla nodiflora leaf extracts and identified n-Hexadecanoic acid, stigmasterol, and beta-sitosterol as promising drug candidates for diabetes, alopecia, cancer, and anti-diuresis, advocating further research into these compounds.
August 2024 in “Biomedical Journal of Scientific & Technical Research” This review discusses the role of steroid 5 alpha reductase 2 in converting testosterone to DHT and its association with conditions like benign prostatic hyperplasia and prostate cancer; it reports no new results.
In this in-vitro study, neem leaf extract, combined with oils from Eucalyptus citriodora and Cymbopogon martini, inhibited dermatophyte growth responsible for tinea capitis, showing potential for developing a treatment formulation against the infection.
March 2024 in “Biomedical reports” This review discusses existing literature on the effects of isoflavone in alleviating PCOS symptoms, highlighting its potential benefits in reducing testosterone levels, improving metabolic profiles, and lowering inflammation and oxidative stress, although findings have been both significant and non-significant.
March 2024 in “World Academy of Sciences Journal” This narrative review explores how exercise might help maintain skin homeostasis disrupted by protein deficiency, potentially by promoting processes like increased collagen synthesis and stimulating anti-inflammatory effects, though the exact mechanisms are not entirely understood.
March 2024 in “Journal of medicinal plants studies” This review comprehensively examines the Hibiscus rosa-sinensis plant, detailing its distribution, physical and chemical properties, bioactive compounds, ethnomedicinal uses, and potential toxicity, providing a broad understanding of its characteristics and health implications.
February 2024 in “PloS one” This study found that certain nutraceuticals did not interfere with tamoxifen's inhibition of estrogen in breast cancer cells and may enhance its effects, suggesting potential as an adjuvant therapy for hair loss in patients undergoing endocrine therapy.
February 2024 in “Digital Library of Theses and Dissertations (Universidade de São Paulo)” This study demonstrated that using a mass spectrometry imaging technique, researchers were able to visualize the incorporation of argan, avocado, and coconut oils into hair fibers, suggesting their potential in cosmetic and alopecia treatments by confirming oil absorption and fiber modification.
January 2024 in “International Ayurvedic medical journal” This study explores how Ayurveda concepts, specifically Prakruti, relate to male pattern baldness, suggesting that individual constitutional types may predict susceptibility to earlier hair loss when influenced by modern lifestyle factors.
January 2024 in “bioRxiv (Cold Spring Harbor Laboratory)” In this study, the researchers found that deleting ceramide synthase 4 in the skin's epidermis alters stem cell differentiation, disrupting hair follicle structure and barrier function, potentially leading to immune responses similar to atopic dermatitis.
January 2024 in “Journal of Natural Remedies” This study found that the petroleum ether extract of Solanum nigrum may promote hair regrowth in testosterone-induced hair loss in rats, as indicated by increased follicle density and anagen/telogen ratio.
This study introduces Kalya Research, an AI-driven tool designed to identify and categorize literature on complementary and alternative medicines, showing its effectiveness compared to Medline in finding relevant alopecia research within the context of breast cancer patients.
September 2023 in “International Research Journal of Modernization in Engineering Technology and Science” This article reviews the growing interest and potential health benefits of nutraceuticals, especially herbal products, highlighting their role in maintaining health, preventing diseases, and improving quality of life, while also discussing developments in nutraceutical research and challenges related to aging skin.
September 2023 in “Journal of pharmacognosy and phytochemistry” This review highlights the medicinal potential and pharmacological activities of the plant Plumbago zeylanica, while emphasizing the critical need for mass propagation methods to address its over-exploitation and support the development of novel herbal medicines.
August 2023 in “bioRxiv (Cold Spring Harbor Laboratory)” This study found that maintaining a low level of Wnt/β-catenin activity is crucial for mammary gland development, as excessive activity inhibits branching and promotes characteristics of hair follicles instead, highlighting its role in skin appendage identity decisions.
June 2023 in “International journal of pharmaceutical quality assurance” This study found that Eclipta alba extracts exhibit 5α-reductase inhibitory activity, with the methanolic extract showing a higher concentration of β-sitosterol compared to petroleum ether extract, indicating potential for treating androgenic conditions like male pattern baldness.
January 2023 in “Journal for ReAttach Therapy and Developmental Diversities” In this study, the n-hexane fraction of Carthamus oxyacantha methanolic extract exhibited significant 5α-reductase inhibitory activity in vitro, suggesting potential therapeutic use for benign prostatic hyperplasia through DHT inhibition.
January 2023 in “Book of Abstracts” COVID-19 can cause different types of hair loss, with telogen effluvium being the most common.
November 2022 in “International journal of biology, pharmacy and allied sciences” In this study, the researchers formulated an herbal shampoo and found it exhibited excellent cleansing properties and foam stability, comparable to commercial shampoos, suggesting it as a safe and cost-effective alternative to marketed formulations.
October 2022 in “International journal of pharmaceutical sciences review and research” This study compared the antioxidant and antidiabetic activities of Hibiscus rosa-sinensis leaf extract and Eclipta alba bark extract, finding that Hibiscus rosa-sinensis exhibited greater antidiabetic activity, whereas Eclipta alba demonstrated stronger antioxidant activity.
October 2022 in “Gadua Journal of Pure and Allied Science” In this study, Trichophyton tonsurans and Microsporum canis were identified as the primary causes of tinea capitis, with terbinafine treatment showing the highest cure rate. Non-commercial kits surpassed real-time PCR commercial kits in specificity and sensitivity for diagnosis.
July 2022 in “Journal of bio innovation” This article discusses the role of Panchakarma, a set of five Ayurvedic therapies, in detoxifying the body, as described in traditional Ayurvedic texts.
July 2022 in “International Journal of Science and Research (IJSR)” This study describes the development of an herbal hair oil using thirteen ingredients to address various hair problems like baldness, dandruff, and hair damage, although the abstract does not report results or evaluate efficacy.
July 2022 in “International journal of KIU” This article outlines the scope, publication standards, and authorship responsibilities of the International Journal of KIU, but reports no new research results.
April 2022 in “JOURNAL OF RESEARCH AND REVIEW IN SCIENCE” This review examines existing scientific literature on African plants with anti-cancer properties and reports no new experimental results.
This study identified a genetic locus associated with rhabdomyosarcoma susceptibility in mice and found that specific differentiation markers are linked to the regression of basal cell carcinoma.
This study found that an herbal extract from Marking nuts, when compared to a standard drug, effectively inhibited the dandruff-causing organism Malassezia furfur and promoted hair growth on mice, suggesting potential use for dandruff treatment and hair rejuvenation.
January 2022 in “Journal of Biomedical Research & Environmental Sciences” This study suggests that eNOS and STAT6 gene polymorphisms may increase the risk of developing PCOS in South Indian women.