July 2025 in “Dermatology and Therapy” This study found that patients with alopecia areata showing low treatment burden responded better to baricitinib compared to those with higher previous systemic treatment exposure.
April 2020 in “Trends in Immunotherapy” In this study, 60% of patients with alopecia totalis showed partial hair regrowth after being treated with triamcinolone acetonide injections, with one patient achieving complete regrowth and responding well to further immunotherapy.
1 citations
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January 2016 in “Dermatology Online Journal” This case report documents a rare instance of triangular temporal alopecia in an adult woman, emphasizing the importance of correct diagnosis to avoid unnecessary treatments, and reviews the literature on TTA.
This study found that the Arabidopsis thaliana protein Formin 2 localizes to plasmodesmata and is crucial for regulating their permeability by anchoring actin filaments, which affects virus susceptibility.
November 2022 in “Journal of Investigative Dermatology” This study found that autologous γdTregs displayed significant protective effects on alopecia areata-affected human scalp hair follicles in both ex vivo and in vivo settings, suggesting potential for future cell-based therapy.
April 2017 in “Leukemia research” This study reported that tofacitinib may be a promising treatment for alopecia areata in adolescents, showing significant hair regrowth with mild adverse effects in a retrospective review.
The researchers reported that asynchronous teledermatology effectively diagnosed and managed non-scarring alopecia in 91.3% of cases within the UPMC network, improving access for underserved populations, with high engagement from Black and Asian patients and significant participation from those living outside Pittsburgh.
May 2025 in “OPAL (Open@LaTrobe) (La Trobe University)” This study found that in a mouse model of alopecia areata, tofacitinib inhibited CD8+ T cell infiltration at hair follicles by modulating linoleic acid metabolism and magnesium pathways, offering insights into potential therapeutic strategies for the condition.
September 2025 in “The Open Dermatology Journal” In this study, the Tibot AI application showed high diagnostic accuracy for adnexal and pigmentary disorders and cutaneous tumors in dermatology, but was less effective for immunological disorders and infestations, suggesting the need for further dataset refinement.
January 2007 in “Frontiers in Medicine” This study found that tofacitinib was an effective and better-tolerated treatment for moderate-to-severe AA compared to SCs, though its efficacy decreased in patients with disease episodes longer than two years.
November 2025 in “PROGRESS IN BIOCHEMISTRY AND BIOPHYSICS” This study found that taurine significantly mitigated DHT-induced androgenetic alopecia in male C57BL/6 mice by promoting hair regrowth, enhancing hair follicle cycle progression, reducing apoptosis, and downregulating key androgen-related signaling pathways, highlighting its potential as a therapeutic candidate for hair loss management.
5 citations
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January 2018 This study optimized a screening assay to identify molecules that inhibit or enhance TRPM5 ion channel activity, which may have implications for treating dysfunctions linked to cardiac arrhythmias and diabetes.
January 2026 in “Universität Zürich, ZORA”
19 citations
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February 2016 in “Journal of The American Academy of Dermatology” This study found that the presence of CD3(+) T-cells within empty follicular fibrous tracts is a reliable indicator for diagnosing diffuse alopecia areata instead of pattern hair loss.
26 citations
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October 2020 in “Pediatric Dermatology” This study found that oral tofacitinib led to clinically significant improvement in alopecia areata severity scores among pre-adolescents, though results varied and further evaluation in clinical trials is needed.
75 citations
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June 2007 in “Journal of Biological Chemistry” This study found that the combination of MT-DADMe-ImmA and MTA selectively induced apoptosis in head and neck squamous cell carcinoma cell lines FaDu and Cal27, but not in normal fibroblasts or MTAP-deficient breast cancer cells.
April 2023 in “Journal of Investigative Dermatology” This study suggests that monitoring CD8+ TEMRA cells in patients with rapidly progressive alopecia areata treated with intravenous corticosteroids could help predict therapeutic outcomes.
January 2016 in “Texas ScholarWorks (Texas Digital Library)” This study suggests that the DORN1 receptor may play a role in eATP-induced changes in stomatal aperture in Arabidopsis thaliana, but not in the eADP signaling pathway.
July 2021 in “Journal of dermatology & dermatologic surgery” In this study, two patients with severe alopecia areata who did not respond well to oral tofacitinib showed more than 50% hair regrowth after a single dose of intramuscular triamcinolone acetonide.
17 citations
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August 2019 in “Archives of Cardiovascular Diseases” In this study, the authors observed that testosterone therapy shortened the QTc interval and normalized T-wave morphology in men with acquired LQTS or TdP linked to hypogonadism, suggesting testosterone may be helpful in treatment.
248 citations
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September 2006 in “PLANT PHYSIOLOGY” This study observed that extracellular ATP is present in Medicago truncatula and correlates with regions of active cell growth, suggesting its integral role in plant development.
June 2025 in “Stem Cell Research & Therapy” This study found that administering adipose-derived stem cells with ATP improved hair regrowth in male mice with androgenetic alopecia, while the combination was less effective in female mice.
1 citations
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April 2017 in “Journal of Investigative Dermatology” This study found that teledermatology significantly reduced wait times and increased appointment availability for uninsured Latino immigrants, effectively triaging 70% of cases without in-person visits.
December 2023 in “Portuguese journal of dermatology and venereology” This study found that trichoscopic examination can effectively differentiate between alopecia areata and trichotillomania, as specific features such as black dots and exclamation marks favor alopecia areata while hair breaking at various lengths and several unique patterns are exclusive to trichotillomania.
10 citations
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December 2005 in “Aktuelle Dermatologie” This study reported that after 7.5 months of treatment, topical Alfatradiol significantly increased anagen hair rates in women and men with androgenetic alopecia, with minimal side effects.
36 citations
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July 2017 in “Journal of controlled release” In this study, a new formulation of all-trans retinoic acid bound to polyvinyl alcohol showed reduced skin inflammation and sustained drug release for up to six days compared to free ATRA in vitro and in vivo.
January 2026 in “Dermatologic Therapy” In this prospective study, researchers identified advanced age, androgenetic alopecia, high levels of lactate dehydrogenase and dihydrotestosterone, and low levels of adenosine triphosphate as independent risk factors for posttransplant telogen effluvium, offering insights for optimizing surgical strategies to reduce PTE risk.
October 2022 in “International journal of dermatology and venereology” This case report describes novel trichoscopic features of anagen effluvium caused by azathioprine in a patient with normal TPMT levels, emphasizing the importance of regular monitoring for adverse effects.
3 citations
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November 2019 in “Journal of Investigative Dermatology” In this study, researchers reported that adenosine stimulated hair shaft elongation in cultured human hair follicles by promoting proliferation and prolonging the anagen phase, suggesting the A2B adenosine receptor in outer root sheath keratinocytes as a promising target for treating hair growth disorders like alopecia.
February 2011 in “Annales de dermatologie et de vénéréologie” This study found that tofacitinib was well tolerated and led to clinical improvement in 77% of potential responders with severe alopecia areata, alopecia totalis, or alopecia universalis.