research Endocrine Treatment of Benign Prostatic Hypertrophy: Current Concepts
New hormonal treatments for enlarged prostate show promise for safer, effective non-surgical options.
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research Molecular Targeted Therapies for Cancer: Sorafenib Monotherapy and Its Combination with Other Therapies
Sorafenib helps some advanced cancers alone or with other treatments, but not all, and research continues to improve its use.
research Social Interest Data as a Proxy for Off-Label Performance-Enhancing Drug Use: Implications and Clinical Considerations
Clinicians should use social and prescription data to track trends in performance-enhancing drug use.
research Gender Differences in Cardiac Hypertrophy
Women generally handle heart enlargement better than men, but it's riskier for them if it occurs; hormones like estrogen offer some protection.
research Polycystic Ovary Syndrome: Special Diagnostic and Therapeutic Considerations for Children
Early diagnosis and treatment of PCOS in young people is important to prevent long-term health problems.
research Efficacy of Topical Finasteride 0.5% vs 17α-Estradiol 0.05% in the Treatment of Postmenopausal Female Pattern Hair Loss: A Retrospective, Single-Blind Study of 119 Patients
Topical finasteride works faster and better than 17α-estradiol for postmenopausal hair loss.
research Testosterone: The Male Sex Hormone
More research is needed to understand how testosterone is maintained in adult males.
research Fluridil, A Rationally Designed Topical Agent For Androgenetic Alopecia: First Clinical Experience
Fluridil safely promotes hair growth in men with androgenetic alopecia.
research The 5α-Reductase Inhibitor Dutasteride but Not Finasteride Protects Dopamine Neurons in the MPTP Mouse Model of Parkinson’s Disease
Dutasteride protects dopamine neurons in Parkinson's mice, but Finasteride doesn't.
research Fluridil, a Rationally Designed Topical Agent for Androgenetic Alopecia
Fluridil safely promotes hair growth in men with androgenetic alopecia.
research Regulatory Roles of Androgens in Cutaneous Wound Healing
Testosterone may slow down wound healing and increase inflammation.
research Hormone Blocking Anticancer Drugs
The document explains how certain drugs block hormones to treat cancers like breast and prostate cancer.
research Hair, Aging, And Environment: Clinical Epidemiological Aspects
Environmental factors like smoking, UV exposure, and poor diet contribute to hair loss and graying, and lifestyle changes can help manage it.
research Gender Differences in Production and Circulating Levels of Sex Hormones and Their Impact on Aging Skin
Men and women experience skin aging differently due to changes in sex hormone levels with age.
research The Effects of Estrogens on Linear Bone Growth
Estrogens are key for bone growth spurts in both boys and girls and affect growth into adulthood.
research Is Hormonal Treatment Still an Option in Acne Today?
Hormonal treatments are effective as a second-line option for moderate-to-severe acne in females, but should be used with caution due to health risks.
research The New Paradigm for Androgenetic Alopecia and Plant-Based Folk Remedies: 5α-Reductase Inhibition, Reversal of Secondary Microinflammation, and Improving Insulin Resistance
Plant-based remedies may treat hair loss by reducing inflammation and improving insulin resistance.
research The Effects of Estrogens on Linear Bone Growth
Oestrogens are key for bone growth during puberty in both boys and girls.
research Intracrine Testosterone Activation in Human Pancreatic Beta Cells Stimulates Insulin Secretion
Testosterone in our bodies helps increase insulin secretion from the pancreas.
research Formestane Preferred as Second-Line Therapy in Advanced Breast Cancer
Formestane is a preferred second-line treatment for advanced breast cancer in postmenopausal women because it's effective and has fewer side effects.
research Molecular Genetic and Endocrine Mechanisms of Hair Growth
Hormones and their receptors, especially androgens, play a key role in hair growth and disorders like baldness.
research Intravaginal Testosterone Improves Sexual Satisfaction and Vaginal Symptoms Associated With Aromatase Inhibitors
Intravaginal testosterone cream improves sexual satisfaction and reduces vaginal discomfort in postmenopausal women on breast cancer treatment without affecting hormone levels.
research Bee Pollen and Honey for the Alleviation of Hot Flushes and Other Menopausal Symptoms in Breast Cancer Patients
Honey and bee pollen can help reduce menopausal symptoms in breast cancer patients.
research Mechanisms of Testosterone Action
Testosterone works in different ways, including direct interaction with its receptor, conversion to other hormones for specific effects on genitalia, hair, bones, and muscle, and changes in body fat and sexual function when low.
research Emerging Drugs for Hypogonadism
New treatments for male hypogonadism are easier to use and target specific tissues to reduce side effects.
research The Genetics of Androgenetic Alopecia
Genes and hormones cause hair loss, with four genes contributing equally.
research Distribution of Copper, Manganese, Selenium, and Zinc in Occipital and Frontal Hair Zones and Hormonal Profiles in Women with Androgenetic Alopecia
Women with a certain type of hair loss have more copper in the back of their head than the front, and treatment can normalize hair but not copper levels.
research Update on Polycystic Ovary Syndrome
The 2018 guideline for PCOS suggests new diagnostic criteria and treatments, but recognizes the need for more research.
research Fundamentals
Finasteride and minoxidil are effective, low-risk treatments for male hair loss, and patient education on these therapies is important.
research Daily Subcutaneous Testosterone for Management of Testosterone Deficiency
Daily subcutaneous testosterone effectively restores testosterone levels in men.