11 citations,
January 1998 in “Dermatology” Spironolactone works well for acne and hirsutism, isotretinoin is very effective for acne and may have antiandrogenic effects, and 5 alpha-reductase inhibitors should be considered antiandrogens.
January 1990 in “Springer eBooks” Some chemicals can permanently or temporarily remove color from skin and hair, which can be distressing and is not well-regulated in cosmetics.
74 citations,
October 1998 in “Journal of biological chemistry/The Journal of biological chemistry” The 190-kbp domain contains all human type I hair keratin genes, showing their organization and evolution.
30 citations,
March 2001 in “Archives of Dermatology” Finasteride can cause one-sided breast enlargement, which disappears after stopping the drug.
40 citations,
July 2008 in “Drug Discovery Today” Current treatments for male pattern baldness include minoxidil and finasteride, with new options being developed.
11 citations,
April 2019 in “Journal of Biological Research” The study identified 12 potential biomarkers for hair loss and how they affect hair growth.
October 2023 in “Apollo medicine” The skin acts like an endocrine organ, producing hormones that affect various body functions and skin health, and understanding this can lead to new treatments.
28 citations,
January 2003 in “Urologic oncology” Suppressing certain hormones might help prevent prostate cancer.
13 citations,
October 2017 in “Bioorganic & Medicinal Chemistry” Optimizing the structure of a specific compound greatly improved its effectiveness and precision for treating diabetic complications.
21 citations,
November 2020 in “Chemical Engineering Journal” The hydrogel with silver and mangiferin helps heal wounds by killing bacteria and aiding skin and tissue repair.
20 citations,
January 2017 in “Epilepsia” Blocking neurosteroid production can lead to more seizures and faster epilepsy onset in rats.
37 citations,
February 2010 in “Psychoneuroendocrinology” Androgen self-administration might be controlled by membrane receptors, not nuclear ones.
1 citations,
August 2004 in “Alternative & complementary therapies” Non-drug methods like diet, supplements, and aromatherapy can help manage hair loss and its emotional impact.
April 2022 in “Indian Journal of Forensic Medicine & Toxicology” PSA can help diagnose high androgen levels in women.
11 citations,
December 2017 in “Orphanet Journal of Rare Diseases” A new mutation in the ST14 gene broadens the understanding of ichthyosis-hypotrichosis syndrome.
January 2019 in “Springer Reference Medizin” Follicle Stimulating Hormone is important for fertility.
January 2022 in “Current Enzyme Inhibition” New nonsteroidal molecules can potentially increase dihydrotestosterone in neurons by blocking certain enzymes, without affecting prostate and seminal vesicle weight.
August 2021 in “Annals of Agricultural and Environmental Medicine” The article concludes that understanding Frontal Fibrosing Alopecia (FFA) is crucial for effective treatment, which includes medication like 5α-reductase inhibitors and hydroxychloroquine.
5 citations,
May 2020 in “Dermatologic Therapy” 5-alpha reductase inhibitors might worsen lung recovery in COVID-19 patients, suggesting a pause in their use.
18 citations,
March 2020 in “Frontiers in Neuroendocrinology” The enzymes 5α-reductase and 3α/β-hydroxysteroid oxidoreductase help create brain-active substances from progesterone and testosterone, which could be used for treatment, but more research is needed to ensure their safety and effectiveness.
March 2024 in “Organic letters” A new method efficiently modifies alkenes to create useful medicinal compounds.
3 citations,
September 2019 in “PLOS ONE” Genetic variations affect dutasteride treatment response for male pattern hair loss.
11 citations,
August 2007 in “Bioorganic & Medicinal Chemistry Letters” Scientists made a chemical (compound 4e) that can be applied on skin to reduce oil production, which can help with acne, but it might cause skin sensitivity to light.
23 citations,
December 2012 in “ChemistryOpen” Probe detects finasteride with high selectivity and low detection limit.
438 citations,
October 2010 in “Oncogene” Keratins help protect cells, aid in cancer diagnosis, and influence cancer behavior and treatment.
45 citations,
October 2015 in “BMC Genomics” Chicken feather growth involves specific genes and shares similarities with hair development.
1 citations,
March 2021 in “F1000Research” Plant-based compounds might be effective, low-side-effect treatments for prostate cancer by blocking a specific enzyme.
95 citations,
May 2012 in “British Journal of Dermatology” Androgens block hair growth by disrupting cell signals; targeting GSK-3 may help treat hair loss.
14 citations,
January 2018 in “Advances in Clinical Chemistry” The document concludes that hormonal biomarkers are key for diagnosing hyperandrogenemia in women and hypogonadism in men.
1 citations,
December 2022 in “Middle East Journal of Science” Permanent hair dyes use chemicals that react with hydrogen peroxide to create color.