research Discovery of a Novel Hybrid from Finasteride and Epristeride as 5α-Reductase Inhibitor
New hybrid compound found to effectively prevent hair loss.
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research Preventive Effects of Monascus on Androgen-Related Diseases: Androgenetic Alopecia, Benign Prostatic Hyperplasia, and Prostate Cancer
Monascus helps prevent baldness, prostate issues, and may be a natural alternative to medications.
research Synthesis, Anticancer, and Molecular Docking Studies of 2-(4-Chlorophenyl)-5-Aryl-1,3,4-Oxadiazole Analogues
The compound 4c showed strong potential as an anticancer agent.
research The Differences Between Aromatizable And Non-Aromatizable Androgens In Relation To Body Composition And Metabolic Syndrome Risk Factors In Men
Testosterone and dihydrotestosterone have similar effects on body composition and metabolic health in men.
research Evaluation of the 5α-Reductase Inhibitor Finasteride on Reproduction and Gonadal Development in Medaka, Oryzias Latipes
Finasteride negatively affects fish reproduction and gonadal development.
research Acne
Acne is a common skin condition linked to diet, hormones, and genetics, and early treatment can prevent scarring.
research Nutraceuticals Known to Promote Hair Growth Do Not Interfere With the Inhibitory Action of Tamoxifen in MCF7, T47D and BT483 Breast Cancer Cell Lines
Nutraceuticals that promote hair growth do not reduce tamoxifen's effectiveness in breast cancer treatment.
research Pharmacology of Anabolic Steroids
Anabolic steroids can build muscle and strength but have risks and need more research on their clinical benefits and side effects.
research A Review of Coumarin Derivatives in Pharmacotherapy of Breast Cancer
Coumarin derivatives show promise as anti-estrogenic agents for treating breast cancer, with some in clinical trials.
research Eph Receptors and Ephrins: Therapeutic Opportunities
Eph receptors and ephrins may be promising targets for treating diseases, but more understanding is needed for effective and safe therapies.
research Sic Transit Gloria: Farewell to the Epidermal Transit Amplifying Cell?
New research suggests that skin cell renewal may not require a special type of cell previously thought to be essential.
research Clinical and Neuropathogenetic Aspects of Human African Trypanosomiasis
The document concludes that diagnosing and treating Human African Trypanosomiasis is challenging, but new treatments like fexinidazole are promising.
research Advanced Nanocarrier- and Microneedle-Based Transdermal Drug Delivery Strategies for Skin Diseases Treatment
Advanced nanocarrier and microneedle drug delivery methods are more effective, safer, and less invasive for treating skin diseases.
research Role of Oxidative Stress in Polycystic Ovary Syndrome
Oxidative stress is a key factor in the development of Polycystic Ovary Syndrome, and weight management can improve symptoms.
research Hair Loss and Herbs for Treatment
Herbs can potentially treat hair loss by inhibiting a key enzyme and promoting hair growth, and deficiencies in zinc, biotin, and iron are linked to hair loss.
research Role of Insulin Resistance and Diet in Acne
Eating high glycemic foods and drinking milk may worsen acne by increasing insulin and IGF-1 levels.
research The Prolactin Receptor as a Therapeutic Target in Human Diseases: Exploring New Potential Indications
Blocking the prolactin receptor might help treat various diseases, but more research is needed.
research Recent Advances in Thiasteroids Chemistry
New sulfur-containing steroid analogs show promise for more targeted medical treatments.
research The Hair Follicle: An Underutilized Source of Cells and Materials for Regenerative Medicine
Hair follicles are valuable for regenerative medicine and wound healing.
research Androgenetic Alopecia: Treatments and Efficacy
Finasteride and minoxidil are effective FDA-approved treatments for androgenetic alopecia.
research A Review of the Dermatological Manifestations of Coronavirus Disease 2019 (COVID-19)
COVID-19 can cause various skin problems, including reactions to protective gear and medication, with different rates reported worldwide, and more research is needed to fully understand these skin issues.
research Drug Repositioning Using In Silico Compound Profiling
Using computers to analyze drugs can find new uses for them, but actual experiments are needed to confirm these uses.
research Rooster Feathering, Androgenic Alopecia, And Hormone-Dependent Tumor Growth: What Is In Common?
Sex hormones affect hair and feather growth and may help manage alopecia and hormone-dependent cancers.
research Sex-Specific Difference of Hippocampal Synaptic Plasticity in Response to Sex Neurosteroids
Sex neurosteroids cause different effects on hippocampal synaptic plasticity in males and females.
research The Androgen Receptor and Its Use in Biological Assays: Looking Toward Effect-Based Testing and Its Applications
Scientists have developed a new method to detect steroid abuse in athletes using cell-based tests, which could be the future of anti-doping methods.
research Alopecia: Unapproved Treatments or Indications
Many treatments for hair loss lack proper testing and FDA approval, so their effectiveness is uncertain.
research Analysis of the FGF Gene Family Provides Insights into Aquatic Adaptation in Cetaceans
Whale genes show changes that help them live in water, like less hair and better flippers.
research Polygonum Multiflorum Extract Supports Hair Growth by Elongating Anagen Phase and Abrogating the Effect of Androgen in Cultured Human Dermal Papilla Cells
Polygonum multiflorum extract helps hair grow longer and fights the effects of hormones that cause hair loss.
research Novel Uses for the Anabolic Androgenic Steroids Nandrolone and Oxandrolone in the Management of Male Health
Nandrolone and oxandrolone could help treat male health issues like muscle loss and low testosterone.
research Sexual Dysfunction Related to Drugs: A Critical Review. Part V: Alpha-Blocker and 5-ARI Drugs
α-Blockers and 5-ARIs for BPH can cause sexual dysfunction, including erectile and ejaculatory issues.