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17α-estradiol is a safe estrogen that might protect the brain and doesn't cause feminization, needing more research for treating brain diseases.

The document concludes that the exact way alcohol causes harm to fetal development is unknown, but it significantly affects nutrient transport to the fetus and a safe level of alcohol during pregnancy is not determined.

Biodegradable polymers can improve cannabinoid delivery but need more clinical trials.

Existing drug dexamethasone may lower death risk in severe COVID-19 cases; more research needed for other drugs.

Minoxidil not effective in preventing chemotherapy-induced hair loss.

CYLD mutations cause a variety of skin tumors with symptoms starting around age 16, and treatments are currently limited.

Non-coding RNAs could help detect and treat radiation damage.

Male-pattern hair loss is largely influenced by genetics, with key genes identified.

Mice without Vitamin D receptors have hair growth problems because of issues in the hedgehog signaling pathway.

Human hair loss may have evolved to help increase brain size.

Wnt, Eda, and Shh pathways are crucial for different stages of sweat gland development in mice.

Follow these guidelines to safely and effectively use energy-based devices in aesthetic treatments.

Drospirenone is a unique progestin with anti-water retention and potential blood pressure benefits, used in birth control and hormone therapy.

Histone modification is key in treating chronic inflammatory skin diseases.

AFM can help diagnose lichen planopilaris by identifying specific hair structure changes.

Thiopurines help treat IBD but require genetic testing to avoid side effects.

Wnt ligands are crucial for hair growth and repair.

The 2017 issue emphasized progress in laser and energy-based skin treatments, but noted the need for more research on certain procedures and technologies.

The document concludes that local flaps are effective for reconstructive surgery in the head and neck, offering good skin match and function.

Certain small molecules can promote hair growth by activating a cellular cleanup process called autophagy.

The research found genetic differences in identical twins that could explain why one twin has a disease while the other does not.

The document concludes that careful design of genetic fate mapping experiments is crucial for accurate cell lineage tracing in mice.

Prolactin contributes to hair loss by promoting hair follicle shrinkage and cell death.

PCOS is caused by both genetics and environmental factors like diet and obesity.

Sex hormones affect hair and feather growth and may help manage alopecia and hormone-dependent cancers.

Clascoterone is safe for the heart, even at high doses.

Epidermal Wnt/β-catenin signaling controls fat cell formation and hair growth.

Some systemic treatments work for nail psoriasis but can have serious side effects.

The substance AS101 can help hair grow by slowing down hair cell aging and boosting a hair growth protein.

Social media can help compare the effectiveness and safety of new arthritis medications.