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This study found that megestrol acetate increases the proliferation, migration, and adipogenic differentiation of adipose-derived stem cells through glucocorticoid receptor phosphorylation.

This study describes a method for labeling and tracking hair follicle stem cells in mouse skin using a Cre/lox recombination system with tamoxifen, providing insights into stem cell behavior and contribution to tissue regeneration.

This study concluded that hair-derived stem cells from older donors may offer a promising alternative for autologous corneal endothelial replacement, potentially benefitting patients of various age groups.

This study describes the process of isolating and analyzing multipotent stem cells from mouse hair follicles for potential use in tissue engineering and regenerative medicine.

This study suggests that adult hair follicle stem cells can survive and potentially differentiate into neuronal cells after being transplanted in a mouse model of traumatic brain injury, indicating promise for TBI therapy.

This review discusses the distinction between platelet-rich plasma and stem cell-based therapies in regenerative medicine, highlighting their different roles and stressing the importance of honest representation by commercial and health entities.

This study describes a protocol for inducing endogenous reactive oxygen species in mouse skin, which stimulates tissue regeneration and promotes burn healing and hair follicle growth.

This review highlights the promising role of stem cell therapy in treating resistant diseases, while also addressing the challenges in production and clinical application, emphasizing the need for standardized manufacturing and quality assurance to enhance efficacy and safety in clinical translational research.

Stem cell research and regenerative medicine have made significant advancements in treating various diseases and conditions.

In this study, transplantation of hair follicle stem cells and nerve growth factor-modified stem cells significantly reduced amyloid deposition and tau hyperphosphorylation in an Alzheimer's disease rat model, suggesting potential as a treatment option.

This study observed that exosomes derived from adipose-derived stem cells significantly enhanced bone marrow mesenchymal stem cell migration and osteogenesis, leading to improved bone regeneration in a rat model of calvarial defects.

This study demonstrated that skin organoids derived from human stem cells can model cutaneous tuberculosis, revealing that fibrosis development in Mycobacterium tuberculosis-infected organoids is linked to the PI3K-AKT and AP1 pathways in fibroblasts, and suggesting the potential for antifibrotic treatment evaluation.

In this review, recent innovations in hair transplantation, such as AI-assisted graft selection, robotic systems, stem cell therapy, and advanced drug delivery techniques, are reported to enhance hair density and thickness for more natural results and higher patient satisfaction by addressing limitations of traditional methods.

This study found that umbilical cord mesenchymal stem cell-derived exosomes improved hair growth in mice with androgenetic alopecia by promoting hair follicle stem cell stemness through the RAS/ERK pathway, suggesting a potential new treatment strategy for this condition.

In this review study, researchers examined existing literature on regenerative medicine and stem cells for androgenetic alopecia and highlighted potential new therapeutic techniques for hair regrowth, emphasizing stem cells' impact on prognosis.

This study highlights that human hair follicle dermal papilla cells and glypicans play crucial roles in regulating hair follicle stem cell differentiation.

This study reviews the potential of stem cell-based therapies, including transplants and exosome treatments, to reactivate hair follicle stem cells and promote hair growth in individuals experiencing pattern hair loss.

This study suggests that administering SH-MSCs gel might decrease IL-6 expression and increase TGF-β expression in alopecia-like rats, indicating potential for alopecia therapy.

This review discusses the application of mesenchymal stem cells and their secretory factors for skin and hair regeneration and reports no clinical results; the authors highlight the progress and call for practical applications.

This study reported that mSKPs and DMSCs share similarities in biological characteristics but exhibit distinct transcriptome profiles, with mSKPs being more immune-related and DMSCs more associated with differentiation and disease pathways.

This review explores the novel roles of white adipose tissue in tissue homeostasis and regeneration, emphasizing its impact on epithelial, muscle, and immune tissues, and reports no new clinical results.

In this review, researchers examined how needle gauge and length impact the viability of human stem cells during injections, emphasizing the balance between minimizing tissue trauma and preserving cell viability to optimize clinical protocols.

This review provides an overview of current research on AD-MSCs, PRP, and biomaterials, highlighting their safety and efficacy in treating soft tissue defects and chronic wounds without major side effects.

This study reported that adipose-derived stem cell-conditioned medium demonstrated anti-tumorigenic effects on B16 melanoma cells both in vitro and in vivo, indicating potential for future melanoma treatment.

This study found that applying Crescina® HFSC lotion for four months effectively increased hair growth and reduced hair loss in males with androgenetic alopecia.

In this study, topical administration of secretome hypoxia mesenchymal stem cells gel increased IL-10 and decreased TNF-α gene expression in a fluconazole-induced alopecia-like model in rats, with the 40 μL dose having the most significant effect.

In this study, researchers used NIR-II fluorescence imaging to track the survival and migration of EPI-NCSCs in rat models, finding that these stem cells aided in repairing facial nerve defects when applied via acellular nerve allografts.

This study found that pediatric HSCT recipients, especially those with chronic graft-versus-host disease, are at risk for developing various nonmalignant late cutaneous changes such as vitiligo, psoriasis, alopecia, and nail changes.

This review examines recent developments in tooth regeneration therapies using mesenchymal stem cells, but it reports no new clinical findings.

In June 2019, the stem cell research field saw major progress, including new clinical trials, FDA approvals, and industry collaborations.