29 citations,
August 2017 in “Skin appendage disorders” IGF-1 may affect hair growth and loss, but more research is needed to confirm effective and safe treatments.
28 citations,
December 2019 in “Skin appendage disorders” Some medications might reverse gray hair, especially those that reduce inflammation or stimulate pigment production, and vitamin B might help.
18 citations,
January 2016 in “Skin appendage disorders” The paper suggests improving diagnosis and treatment of telogen effluvium but does not recommend a new classification system.
8 citations,
December 2017 in “Skin appendage disorders” WNT7A gene expression is higher in early stages of androgenetic alopecia, showing the role of WNT pathway, apoptosis, and inflammation in the disorder.
7 citations,
January 2018 in “Skin appendage disorders” The document suggests recognizing "trichiatrists" as doctors specializing in hair and scalp health, using evidence-based treatments.
4 citations,
December 2019 in “Skin appendage disorders” Using Platelet-Rich Plasma injections for male-pattern baldness didn't significantly improve hair growth.
4 citations,
October 2019 in “Skin appendage disorders” PRP injections safely increase hair density and thickness in androgenetic alopecia.
1 citations,
January 2021 in “Skin appendage disorders” Chemotherapy patients don't all lose their hair due to factors like hair growth rates, age, genetics, and the type of drugs used.
January 2024 in “Skin appendage disorders” Using growth factors and microneedling shows promise for hair regrowth in Alopecia Areata, but more research is needed.
51 citations,
December 2017 in “Skin Appendage Disorders” Stress may trigger hair loss by affecting immune protection in hair follicles.
October 2024 in “Skin Appendage Disorders” PRP is popular for hair restoration but needs better research methods to confirm its effectiveness and safety.
June 2024 in “Skin Appendage Disorders” Both PRP and MZT treatments can significantly improve hair growth in patients with androgenetic alopecia.
April 2024 in “Skin appendage disorders” Environmental pollutants can damage hair health and cause hair loss.
January 2023 in “Skin appendage disorders” Low-dose oral minoxidil may help treat hair loss but is not FDA-approved and can cause side effects like unwanted hair growth and heart issues.
January 2023 in “Skin appendage disorders” Scalp microinfusion is a new method for treating hair loss that shows promise but needs more research for standardization.
1039 citations,
February 2009 in “Nature Reviews Molecular Cell Biology” Skin stem cells are crucial for maintaining and repairing the skin and hair, using a complex mix of signals to do so.
4 citations,
May 2014 in “Biochemical Society Transactions” Environmental cues can change the fate and function of epithelial cells, with potential for cell therapy.
127 citations,
December 2007 in “Journal of Investigative Dermatology” Mice hair growth patterns get more complex with age and can change with events like pregnancy or injury.
77 citations,
April 2016 in “Science Advances” Researchers created a fully functional, bioengineered skin system with hair from stem cells that successfully integrated when transplanted into mice.
43 citations,
December 2013 in “Seminars in Cell & Developmental Biology” Genetic mutations can cause hair growth disorders by affecting key genes and signaling pathways.
8 citations,
May 2021 in “Bioengineering & translational medicine” Hair growth environment recreated with challenges; stem cells make successful skin organoids.
7 citations,
March 2017 in “Journal of dermatology” The conclusion is that accurately identifying folliculosebaceous tumors requires understanding their clinical signs and microscopic features.
5 citations,
September 2015 in “BMC Medical Genetics” The EDAR gene mutation leads to thinner and more deformed hair shafts.
June 2023 in “Journal of cosmetic medicine” Hair follicle stem cells and mitochondria are key for hair growth, and targeting their activity could lead to new hair loss treatments.
139 citations,
August 2018 in “Development” The niche environment controls stem cell behavior and plasticity, which is important for tissue health and repair.
72 citations,
July 2012 in “Journal of Investigative Dermatology” Mice lacking a key DNA methylation enzyme in skin cells have a lower chance of activating stem cells necessary for hair growth, leading to progressive hair loss.
55 citations,
October 2014 in “Development” Wnt, Eda, and Shh pathways are crucial for different stages of sweat gland development in mice.
31 citations,
January 2021 in “Experimental Dermatology” Skin organoids are a promising new model for studying human skin development and testing treatments.
31 citations,
September 2013 in “Stem Cells” Smad1 and Smad5 are essential for hair follicle development and stem cell sleepiness.
29 citations,
December 2016 in “The EMBO Journal” Gata6 is important for protecting hair growth cells from DNA damage and keeping normal hair growth.