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This study observed that hereditary factors were associated with acne duration but not severity, and found a potential role of CYP450 1A1 polymorphisms in acne pathogenesis.

This study evaluated how often racial and ethnic minorities were included in phase II and III randomized controlled trials for androgenetic alopecia conducted in the United States in the past decade, aiming to inform more personalized treatment approaches.

This review highlights the potential of integrating point-of-care testing with allele-specific amplification techniques like AS-PCR, AS-LAMP, and AS-RPA to improve the efficiency, accuracy, and affordability of genotyping single nucleotide polymorphisms associated with human diseases.

This study found pathogenic mutations in genes EDA, EDA1R, and EDARADD in 101 out of 124 hypohidrotic ectodermal dysplasia patients, revealing 23 novel mutations and indicating genetic variability.

This review discusses recent advances in using extracellular vesicles as a potential treatment for alopecia and highlights ongoing challenges in their clinical application and mass production; no new clinical results are reported.

Six new genes linked to early hair loss were found, which also surprisingly connect to Parkinson's disease and lower fertility.

This study identified a novel pathogenic splice-site variant of the LAMB3 gene in patients with junctional epidermolysis bullosa, highlighting the importance of gene sequencing for diagnosis.

This study found that Han Chinese women carrying the rs6152A allele had a significantly higher risk of developing polycystic ovary syndrome compared to those with the rs6152GG genotype.

This review discusses the development and potential therapeutic applications of adenosine receptor agonists and positive allosteric modulators, noting that while many clinical trials have been unsuccessful, initial results for new compounds are promising.

This study found that genetic predictions of male pattern baldness derived from European data do not accurately predict baldness in African populations, highlighting significant continental differences in genetic architecture and evolutionary history.

This study identified putative causal mutations for PCOS among first-degree relatives, although functional analysis of a specific GDF9 mutation was unsuccessful.

This pharmacovigilance study found strong disproportionality signals suggesting an association between finasteride and Peyronie's disease-related clinical features, but the evidence does not confirm a causal link.

In this publication, independent scholar Jeffi Chao Hui Wu presents a comprehensive civilization archiving system spanning fourteen domains, highlighting innovative AGI limitations and physiological case reversals, published in ten languages and integrated into global academic infrastructures.

This study observed that N-palmitoylethanolamine (PEA) may relieve pain by enhancing de novo neurosteroid synthesis, evidenced by increased allopregnanolone levels and protein expression in pain models, dependent on PPAR-α.

In this study, researchers found that the novel gene circCFAP20DC enhances the proliferation of goat follicular granulosa cells by activating the RB pathway, facilitating their progression from the G1 to S phase during follicular development.

In this study, researchers found that applying topical aprepitant, which blocks substance P receptors, significantly reduced facial dermatitis and hair loss in rats experiencing erlotinib-induced skin side effects, highlighting the neurogenic inflammation's role and the protective effect of ROS inhibition.

In this case-control study, EGF levels were significantly higher in patients with alopecia areata than in healthy controls, and these elevated levels positively correlated with the severity and extent of the disease, suggesting EGF as a potential marker for alopecia areata severity.

This study found that higher baseline expression of SRD5A2 in prostate tissue was associated with a better response to finasteride in men with benign prostatic hyperplasia.

This study found that taurine and apocynin together created a synergistic effect by significantly reducing burn area damage and enhancing tissue recovery in the burn zone of stasis in rats by day 21.

This study found no correlation between serum PSA levels and the severity of androgenetic alopecia at baseline in men.

In this case series, three patients with advanced non-small cell lung cancer experienced severe skin eruptions and scarring alopecia after treatment with amivantamab, highlighting the critical need for prompt recognition and management of these adverse effects to minimize treatment interruptions.

This case report describes novel trichoscopic features of anagen effluvium caused by azathioprine in a patient with normal TPMT levels, emphasizing the importance of regular monitoring for adverse effects.

In this study, a novel compound named AH-001 demonstrated effective androgen receptor protein degradation, reducing hair loss progression in a mouse model of androgenetic alopecia, with minimal systemic exposure and side effects, suggesting potential for safer treatment.

This study introduces "alopecia areata in a male or female pattern distribution" as a new clinical subtype of alopecia areata, observed in three adult cases, to enhance diagnostic precision and treatment personalization.

This study proposes reclassifying PCOS into two distinct phenotypes based on androgen levels and suggests androgen supplementation may overcome IVF resistance in one group with advancing age.

This review discusses the acyl-CoA synthetase very-long-chain (ACSVL) enzyme family, including its biochemical characteristics, tissue expression, and involvement in lipid metabolism, but presents no new experimental results.

This study found that P. cornucopiae extract showed antioxidant and protective effects on human skin fibroblasts, suggesting its potential as an antiaging agent by preventing oxidative stress-induced collagen breakdown.

This research investigated the role of EphA1 in embryonic and adult tissues, generating mouse models suggesting potential links to skin and colon cancer, sepsis, and post-traumatic injury.

This study reviewed current scientific evidence on the use of exosomes for treating alopecias, finding they may stimulate dermal papilla cell proliferation and modulate inflammation, though challenges in standardization and long-term efficacy remain.

This study describes various clinical phenotypes associated with FOXN1 mutations, finding that affected individuals may develop different severities of immunodeficiency based on their genetic mutations.