November 2025 in “ACS Omega” This study found that compounds from *Tectona grandis* leaves showed moderate inhibition of steroid 5α-reductase, a factor in androgenetic alopecia, and exhibited anti-inflammatory properties by inhibiting nitric oxide and pro-inflammatory cytokines IL-1β and IL-6 in vitro, suggesting potential dual-action benefits for AGA management.
This study found that nanostructured lipid carriers enabled effective follicular delivery and accumulation of anti-hair loss drugs like dutasteride in mice, suggesting potential for reduced dosage frequency.
October 2025 in “Biomedicines” This study suggests that Terminalia chebula fruit extract may promote hair growth in androgenetic alopecia by activating specific signaling pathways and inhibiting 5α-reductase, showing effectiveness comparable to finasteride.
January 2026 in “Case Reports in Dermatological Medicine” In this case study, a young female with aseptic and alopecic nodules of the scalp achieved full resolution without recurrence using intralesional steroids.
17 citations
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September 2003 in “Journal of Investigative Dermatology Symposium Proceedings” This study found that anthralin and mechlorethamine were the most effective therapies among those tested in AA-affected rodent models, providing a basis for further analysis of their mechanisms in Alopecia Areata.
3 citations
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May 2024 in “Journal of Drug Delivery and Therapeutics” This review examines the therapeutic potential of Aftimoon (Cuscuta reflexa), focusing on its pharmacological properties and traditional uses in Unani medicine for various ailments, and highlighting its range of biological activities, including antioxidant and anti-inflammatory effects.
1 citations
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September 2024 in “Indian Journal of Postgraduate Dermatology” In this report, trichoscopy was highlighted as a valuable tool for diagnosing temporal triangular alopecia in children due to its ability to reveal distinctive patterns that differentiate it from similar conditions like alopecia areata, eliminating the need for invasive biopsy.
16 citations
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June 2005 in “Clinical and Experimental Dermatology” In this study of 30 severe anorexia nervosa patients, true acquired pili torti was not found although twisted hair was observed in 6.6% of cases.
February 2024 in “Journal of ayurveda and integrated medical sciences” In this case study, a 22-year-old female with iron deficiency anaemia showed significant symptom improvement and haemoglobin increase after a month of Ayurvedic treatments and iron-rich dietary supplements.
November 2025 in “International Journal For Multidisciplinary Research” This study focused on treating 'Indralupta' or alopecia areata using Ayurvedic methods such as Prachanna Karma, finding it promising for improving perifollicular vascularization and addressing hair loss attributed to vitiated Rakta as defined by traditional texts.
March 1994 in “Proceedings of the British Society of Animal Production” This study investigated hair fibre growth in Angora and Cashmere goats, finding differences in growth rates and seasonal dependencies, and examined the effects of prolactin and melatonin on protein deposition in hair follicles.
November 2022 in “Journal of Drug Delivery and Therapeutics” This review discusses the concept and treatment of diffuse hair loss, known as Intithār al-Sha‘r, in the Unani system, drawing from classical Unani literature without reporting new clinical results.
29 citations
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January 2004 in “Experimental Dermatology” In this study, anthralin treatment led to hair regrowth in alopecia areata-like affected C3H/HeJ mice, suggesting it may be an effective therapy for this condition.
April 2023 in “International journal of research in Ayurveda and pharmacy” This study reported significant symptom improvement in a 30-year-old female with hypothyroidism after Ayurvedic treatment with Kanchnar twak kwath, Shunthi churna, and Nimb tail nasya, noting a reduction in TSH levels from 18.65 to 6.92 post-treatment.
March 2026 in “Zenodo (CERN European Organization for Nuclear Research)” This study investigates the potential effects of Shatpushpa oil MatraBasti on menstrual regulation and obesity in women with polycystic ovary syndrome; results are yet to be determined.
December 2025 in “Zenodo (CERN European Organization for Nuclear Research)” In this review, the authors explore the Ayurvedic approach to managing hair loss, emphasizing the use of purification, pacification, and rejuvenation techniques, along with herbs like Bhringraj, Amalaki, and Brahmi, to restore hair health and balance the body's systems.
January 2014 in “IOSR journal of pharmacy” This case report identifies alopecia universalis as a probable adverse drug reaction to adalimumab in a patient with psoriasis and psoriatic arthritis.
January 2026 in “International Ayurvedic Medical Journal” This case report observed significant improvement in a 23-year-old male with Khalitya/Androgenetic alopecia after undergoing Ayurvedic management.
November 2021 in “Journal of Regenerative Biology and Medicine” This article discusses alopecia areata, an inflammatory hair loss condition with largely unexplored causes, but provides no new research findings.
January 2026 in “Zenodo (CERN European Organization for Nuclear Research)” This study reviews classical Ayurvedic texts and modern research on Amalaki, finding significant benefits for lipid profiles, blood glucose, and inflammation in clinical trials, while also suggesting potential benefits for liver, hair, skin, eyes, cognition, and respiratory health based on preclinical data and traditional claims.
6 citations
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March 2021 in “Journal of the American Academy of Dermatology” This study found that the Brigham Eyelash Tool for Alopecia (BELA) is a reliable measure for assessing eyelash loss in alopecia areata patients, demonstrating high inter- and intrarater reliability.
October 2023 in “Regular and Young Investigator Award Abstracts” This study found that Baricitinib significantly reduced hair loss and immune response in a mouse model of alopecia areata.
45 citations
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December 2018 in “Lasers in Medical Science” In a 24-week randomized trial, this study found that the RAMACAP laser helmet significantly increased hair density and diameter in androgenetic alopecia patients compared to a sham device, although limitations included a small sample size and potential issues with the control used.
This study found that an ethanolic extract of Semicarpus anacardium nuts reduced blood glucose levels and improved enzyme activities related to carbohydrate metabolism in normal rats.
September 2016 in “Journal of the Society of Cosmetic Scientists of Korea” This study found that Resina Pini and its main component, abietic acid, significantly promoted hair growth in a mouse model of androgenic alopecia by inhibiting 5α-reductase activity.
August 2023 in “Journal of inflammation research” This case report observed alopecia universalis, a complete hair loss condition, in a patient during a clinical trial with the angiotensin receptor-neprilysin inhibitor sacubitril/alisartan, indicating that ARNI therapy might be associated with such cutaneous reactions.
6 citations
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October 2022 in “Journal of Ayurveda and Integrative Medicine” This case study observed complete remission of folliculitis decalvans in a 24-year-old male after treatment with Ayurveda medicine and leech therapy, with sustained improvement over 33 months, suggesting potential effectiveness compared to other treatments.
June 2025 in “Journal of Drug Delivery Science and Technology” A dissolving microneedle patch with dutasteride offers effective, long-lasting hair loss treatment with fewer side effects.
May 2025 in “Journal of Nanobiotechnology” This study reported that an ATRA-loaded nanostructured lipid carrier gel (ATRA-NLC-Gel) improved symptoms of alopecia areata in mice by enhancing transdermal drug delivery, reducing skin irritation, and promoting hair regrowth through targeted follicle enrichment and pathway activation.
6 citations
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March 2014 in “Annals of Pharmacotherapy” This case report suggests that anidulafungin may be associated with hair loss, highlighting the need for physicians to monitor this potential adverse effect.